44 results about "Suppository Dosage Form" patented technology

The invention discloses a medicinal composition for treating gynecological inflammation, and belongs to the field of Chinese medicament. The medicinal composition consists of collagen and/or Chinese medicaments for releasing toxin and sterilizing such as collagen and lizardtail, glabrous greenbrier rhizome, Vietnamese sophora root and the like which are prepared into a plurality of dosage forms bycombining the prior art, and is mainly used for treating vaginitis, pelvic inflammation, urethritis and cervicitis diseases. The technical scheme overcomes the defects that the prior externally-applied preparations such as lotion, gel, suppository, ointment and the like have extremely slow response, longer disease course, repeated outbreak and the like, and creatively combines and applies the collagen and the Chinese medicament, can accelerate the healing of ulcer and erosion faces caused by the inflammation, and can greatly shorten the required time for tissue repair.

A composition for treating a subject is provided. The composition includes antigen specific dimeric secretory IgA and pentameric IgM therapeutic. A process for manufacturing a medicament for the treatment of C. difficile associated disease in a human is also provided that the modification of antigen specific dimeric secretory IgA and pentameric IgM with secretory component to form a antigen specific dimeric secretory IgA and pentameric secretory IgM therapeutic. The antigen specific dimeric secretory IgA and the pentameric secretory IgM therapeutic is then mixed with formulating agents to create a capsule, tablet, liquid or suppository dosing form. The therapeutic is amenable to enrobement directly through microencapsulation or the dosing form is coated with an enteric coating. A method of C. difficile treatment with the therapeutic is also provided that is amenable to supplementation with concurrent or prior antibiotic administration.

The invention relates to a compound metronidazole expansion suppository. The compound metronidazole expansion suppository is vaginal suppository prepared by metronidazole, total saponins of ginseng stems and leaves, and vitamin E which are taken as active ingredients, and proper matrix; an expandable expansion carrier is arranged in the suppository; a medicated layer formed by the active ingredients and the matrix is coated on the surface of the expansion carrier; after saturated water absorption, the expansion carrier has the radial expansion value more than 1.1. The invention also provides a detection method of the compound metronidazole expansion suppository. The method comprises the contents such as expansion value measurement, weight difference measurement, etc. The expansion suppository applies six original technologies including 'one-time suppository filling integrated forming' technology, 'inner core expansion factor control' technology, 'human engineering suppository type' technology, 'treatment-cleaning integration' dosage form, 'vaginal inner-attached administration' technology and 'side leakage prevention suppository body design'; the medicated layer of the compound metronidazole expansion suppository is fully contacted with the inner wall of the vagina, so that liquid medicine is prevented from flowing outside; the compound metronidazole expansion suppository also has the effect of cleaning the vagina so as to prevent superinfection.

The present invention relates to a suppository manufacturing method and suppository manufacturing equipment. The method comprises the simultaneous delivering of hot melt medicaments and dry cold wind with fine powder into a centrifugal spray cooling granule making machine. In this manner, medicament granules with specified diameter are prepared. The medicament granules are sent to a die and are compressed so as to get suppositories. The equipment comprises a container for hot melt medicaments and a blowing apparatus for delivering dry cold wind. The container is connected to an atomizing device at the tower top of the centrifugal spray cooling granule making machine through pipes. The blowing apparatus, connected to the centrifugal spray cooling granule making machine through the air ducts, is fit to produce swirling wind inside the centrifugal spray cooling granule making machine. A material adding device for adding fixed amount of fine powder is communicated with the air ducts. The material outlet of the centrifugal spray cooling granule making machine is connected with an oscillating sieve for sieving the medicament granules with specified diameter. According to the embodiments of the invention, the strength of the suppositories increases; the specific surface area of the suppositories enlarges; the phenomenon of layering and chromatography in the suppositories can be avoided and the outer surface of the suppositories will not have flashes.

The invention relates to a drug for treating gynecological diseases and a preparation technology thereof, belonging to the technical field of drug manufacture and including the preparation technology of the drug. The components of the main raw materials are characterized by: 30-350 parts of bark of chinese corktree, 30-350 parts of lightyellow sophora root, 20-250 parts of fructus kochiae, 10-110 parts of Hairyvein Agrimonia Herb and Bud and 1-8 parts of borneol. The raw materials are mixed to be prepared into a suppository dosage form through ethanol extraction. When in use, the active ingredients of the drug can reach the focus directly, therefore the drug has strong pertinence and concentrated acting force and causes no irritation and very little toxic or side effect to the digestive system of human body after use. The drug has few raw materials and simple preparation technology, and is proved to have rather obvious effect of treating bacterial vaginosis and colpomycosis by die pharmakodynamik experiments, as well as the functions of clearing heat and drying dampness, killing insects and relieving itching.

The present invention relates to a new gynecological Thousand-Gold preparation and its preparation method. Said new gynecological Thousand-Gold preparation not only can be used for effectively cuing female pelvic inflammation, but also can be used for effectively curing male pelvic inflammation. Said preparation can be made into various oral dosage forms, such as tublet, granules, powder, capsule and pills, etc.

A vaginal tablet for treating cervicitis and cervical erosion is prepared from phellodendron bark, flavescent sophora root, catechu, baked alum and borneol. Its preparing process is also disclosed.

The invention relates to a split type suppository as well as a preparation method and a use thereof. The split type suppository comprises a suppository body with a groove and an expansion carrier which is mutually separated from the suppository body, wherein the suppository body mainly comprises active ingredients and a matrix; the groove is composed of a groove side wall and a groove bottom; the diameter of the cross section of the groove is 1/3-2/3 that of the cross section of the suppository body; and the length of the groove is 1/5-4/5 the length of the suppository body. The split type suppository provided by the invention not only can avoid the examination and approval of the drug administration agencies, but also can refrain the expansion carrier from adsorbing the active ingredients and the matrix in the suppository body due to splitting of the suppository body and the expansion carrier.

The invention discloses a hemorrhoid suppository filling liquid medicine stirring and mixing device. The hemorrhoid suppository filling liquid medicine stirring and mixing device comprises a mountingshaft, a top cover, a stirring kettle, a first conveying pipe, a first pressure pump, a collecting box, a heater, a heating coil and supporting legs; the mounting shaft is provided with a spiral bladefor spirally and upwards conveying and stirring liquid medicine in the stirring kettle; a motor for driving the mounting shaft to rotate is arranged on the top cover; an input end of the first pressure pump is connected with the first conveying pipe, and an output end is connected with the collecting box; a discharging pipe is arranged on the collecting box; a first control valve is arranged on the first conveying pipe; the end, away from the first pressure pump, of the first conveying pipe is communicated with the stirring kettle through a discharging hole; the heating coil is spirally arranged on the outer peripheral surface of the stirring kettle and is connected with the heater; the supporting legs are arranged at the bottom of the stirring kettle. The spiral blade is used for stirring medicine powder and a matrix, the medicine powder and the matrix are spirally conveyed upwards from the middle of the stirring kettle and scattered at the top of the stirring kettle, the medicine powder in the stirring kettle is uniformly dispersed, and the medicine powder can be uniformly mixed with the matrix.

The invention discloses a traditional Chinese medicine suppository for treating metrorrhagia and metrostaxis, which is prepared by the following main raw materials in parts by weight: 2-6 parts of raw sabinene, 4-9 parts of radix sophorae flavescentis, 8-20 parts of chinese osbeckia, 3-9 parts of fructus malvae, 4-9 parts of cuttlefish bone, 3-9 parts of fructus cnidii, 0.5-1.2 parts of red upborne elixir, 9-12 parts of fructus leonuri, and 30-60 parts of oleum sesami. The traditional Chinese medicine suppository has the effects of invigorating qi and blood, activating the blood circulation to dispel blood stasis, as well as stopping bleeding and regulating menstruation, and has a good treatment effect on the metrorrhagia and metrostaxis; the dosage form is suppository which can play local roles in lubricating, antibiosis, insect killing, convergence, pain stopping, itching relieving and other local roles in an orifice, and can also avoid the stimulation of drug on a gastric mucosa, and cannot have any toxic and side effect to a patient.

The invention discloses a prostatitis pad plaster, which belongs to the technical field of a medical plaster. The prostatitis pad plaster comprises the following raw materials in parts by weight: 30-80 parts of raspberry, 20-50 parts of plantago, 40-60 parts of dianthus superbus, 35-60 parts of polygonum aviculare, 30-60 parts of Sichuan achyranthes, 40-55 parts of Pyrrosia lingua, 38-48 of Lygodium japonicum, 20-60 parts of polyporus, 45-55 parts of dandelion, 40-60 parts of Semen Astragali Complanati, 30-60 parts of fructus rosae laevigatae, 30-68 parts of saururus chinensis, 40-55 of SemenCuscutae, and 10 to 100 parts of borneol. The prostatitis pad plaster prepared by the invention is applied in a manner that avoids the discomfort of a gel, a suppository, an umbilical paste, a physiotherapy instrument, and other external products, and the side effects caused by the medication. The prostatitis pad plaster is safer, more comfortable, non-invasive, and painless, has no side effects,and has rehabilitation and physiotherapy on prostatitis, prostate hypertrophy syndrome.

The invention relates to the technical field of medicine manufacturing, and concretely relates to a nifuratel nystatin suppository manufacturing method and equipment. Primary suppositories prepared by a centrifugal spray granulator are conveyed into a cloth bag, air is supplied into a drying box through an air supply assembly to dry the primary suppositories, after drying is completed, a first electric push rod is started to make the cloth bag protrude, and the dried suppositories fall into a collection hopper under the action of gravity and then are conveyed into a screening box, and the suppositories which do not conform to specifications and sizes are screened out through a first screening mechanism and a second screening mechanism in sequence, so that finished suppositories are obtained. Compared with a traditional mode that all procedures are independently arranged, the manual intervention degree is high, the structure is highly integrated, the manual intervention degree is low, and the suppository preparation efficiency is improved.

The invention discloses a staphylococcus aureus bacteriophage suppository and application thereof in treatment of dairy cows. The suppository is prepared from the following raw materials in percentage by mass: 25-75% of a water-soluble matrix, 1-4% of a bacteriophage stock solution, 5-10% of an effervescent disintegrant, 10-35% of a lubricant, 1-3% of a foaming agent, 1-2% of resveratrol and 2-5% of traditional Chinese medicine auxiliary materials. The effervescent suppository has the beneficial effects that the effervescent suppository, the resveratrol and a plurality of traditional Chinese medicine auxiliary materials are matched, and the synergistic or antagonistic effect of the effervescent suppository, the resveratrol and the traditional Chinese medicine auxiliary materials is utilized, so that the curative effect can be effectively improved or the adverse reaction can be reduced, the effects of clearing heat and promoting diuresis, promoting blood circulation and removing blood stasis, and sterilizing and diminishing inflammation can be achieved, and the symptom of dairy cow uterus bacterial vaginitis can be quickly relieved; and the medicine is low in cost, does not cause economic burden after being used for a long time, and is an ideal medicine for treating bacterial vaginitis.

The invention provides a medical biological dressing suppository for treating gynecological diseases, diseases of prostate or anorectal diseases and an application thereof. The medical biological dressing suppository comprises a main drug and auxiliary materials. The main drug comprises echinacea and chitosan. According to the invention, echinacea is applied to an external medicine for the first time. Relative to internal medicines, the external medicine can directly reach the diseased region with a small dosage, so that a better treatment effect is realized. Even though echinacea is mutually fused with chitosan and is adsorbed to the affected skin or the surface of mucosa to form a protective layer, synergic effects of maintaining effective delivery concentration to echinacea and prolonging the action time of the medicine and the like are obtained by means of good biocompatibility of chitosan. In addition, echinacea adsorbed to the affected skin or the surface of mucosa further can effectively stimulate generation of glucosaminidase and growth of myofibroblast to enhance the defense capacity of the skin or mucosa. Echinacea purpurea further can simulate the immune system, increase the quantity and activity of leukocytes and enhance the treatment effect of independent medication.