15 results about "Suppository Dosage Form" patented technology

The utility model belongs to the technical field of filling equipment, and particularly relates to a medicine filling device based on a suppository lever principle. Comprising a rack, a material clamping device and a filling device are arranged on the rack, a pump body is provided with a main feeding channel and a plurality of filling channels, and a material suction cavity communicates with the main feeding channel through an injection cavity; the material suction piston assembly comprises a plurality of filling piston rods movably arranged in the corresponding material suction cavities, and the filling piston rods are driven by a first driving device; the injection assembly comprises a plurality of injection rods movably arranged in the corresponding injection cavities, feeding grooves are formed in the outer walls of the injection rods, and during material suction, the material suction cavities communicate with the main feeding channel through the feeding grooves; an injection channel is formed in the injection rod, and the material suction cavity communicates with the injection head through the injection channel during material injection; and the injection rod is driven by a second driving device. The suppository injector has the characteristics of simple structure, convenience in charging metering adjustment, high suppository injection precision, good sealing performance, high working efficiency, long service life and the like.

The invention relates to the technical field of medical instruments, in particular to a suppository shaping and boosting integrated device which comprises a main body assembly, a boosting shell is included, a containing cavity and a containing groove are formed in the boosting shell, a guide pipe and a mold are arranged in the containing cavity, and cooling fins and a reset structure are further arranged on the outer wall of the mold; a pushing structure is further arranged in the containing cavity and comprises a screw rod, a piston piece is arranged at the end of the screw rod, and the piston piece extends into the guide pipe and is used for pushing the paste; the screw rod is driven by a single power source, and the screw pitch difference design of the spiral groove and the moving column is matched, so that the movable sleeve quickly moves in the early stage to drive the supporting plate to be accurately in place, synchronously and slowly moves with the screw rod in the later stage to complete pushing and adapt to the time rhythm of paste cooling and shaping, and the working efficiency is greatly improved; separation and reset of the mold depend on sliding fit of a wire groove and a guide column and multi-component linkage of a reset structure, separation is stable, reset is accurate, paste microcoagulation is rapidly achieved in cooperation with a cooling fin, and suppository shaping consistency and integrity are guaranteed.

The present application relates to a polypeptide LLLE derived from sturgeon cartilage and its application, in particular to a polypeptide LLLE derived from sturgeon cartilage and its application in improving obesity caused by food pesticide residues. The sequence of the polypeptide LLLE is: Leu-Leu-Leu-Glu; based on it, various pharmaceutically acceptable dosage forms can be prepared, including but not limited to injection, tablet, capsule, pill, granule, syrup and other oral liquid, suppository; it can effectively alleviate fat accumulation and blood lipid abnormality caused by chlorpyrifos chronic exposure and high-fat diet, that is, control obesity caused by chlorpyrifos chronic exposure, significantly reduce the content of serum total glyceride, total cholesterol and low-density lipoprotein cholesterol, improve the content of serum high-density lipoprotein cholesterol and regulate blood lipid. Moreover, the food-derived oligopeptide is stable and easy to absorb, safe and environmentally friendly, and has no toxic and harmful effects on human body.

Formulations comprising hydrocortisone are disclosed in a suppository for methods of treating ulcerative colitis and other gastrointestinal diseases and disorders. Administering a single hydrocortisone suppository once a day achieves remission or reduction of a symptom, optionally followed by a period of time in which the dosage is reduced.

A natural orifice synergistic drug delivery device comprises a slender hard rod-shaped body (11) and a soft body (12) wrapping the rod-shaped body (11), the rod-shaped body (11) is provided with a rod-shaped body head part (111) entering a natural orifice opening during use, a rod-shaped body middle part (112) and a rod-shaped body tail part (113) located outside the natural orifice opening during use, and the drug delivery device (1) is provided with a liquid injection port (101), a liquid passage (10) and a radial liquid outlet (102). The head area of the soft body (12) is provided with a hollow flexible wrapping part (125) and / or a suction cup part (127), the internal space (1250) of the flexible wrapping part can at least contain a part of the tail part (23) of the solid suppository, and during use, the solid suppository (2) is firstly inserted into the flexible wrapping part (125) and / or adsorbed on the suction cup part (127), and then the administration device is slowly inserted into a natural orifice through an opening of the natural orifice. And then a liquid medicament is injected through the liquid injection port, the dosing device is pulled out of the opening of the natural cavity, and the solid suppository is retained in the natural cavity.

The invention relates to the field of pharmaceutics and medicine, namely, to a new dosage form of cortexin, rectal suppositories, capable of normalizing brain functions and characterized by efficacy and safety comparable to an injectable form. The invention also relates to a rectal cortexin composition in a suppository form, the composition comprising cortexin in a pharmacologically effective amount and a suppository base.

The utility model relates to the technical field of medical instruments, in particular to an anorectal suppository dosing device. Comprising an administration end provided with a plurality of separable side walls, a medicine carrying cylinder, a push rod used for pushing suppositories in the medicine carrying cylinder, and a buffer component used for reducing the pushing speed of the push rod. The inner wall of the separable side wall is provided with a lubricating bag for wrapping a lubricating agent, and the separable side wall is provided with a hole for the lubricating agent to seep; according to the utility model, the lubricating bag and the hole are arranged, so that a lubricating agent can uniformly seep from the hole after being extruded, the lubricating agent is prevented from being smeared by hands before administration, and the lubricating operation is simple, rapid, clean and sanitary; by arranging the buffer component, the push rod pushing speed is controllable, the push rod can be pulled back easily, self-administration of a patient can be achieved easily, privacy of the patient can be protected, pain of the patient can be relieved, and the treatment enthusiasm of the patient for using the anorectal suppository is improved.

The utility model discloses a painless bolt pushing device used after anorectal operation, which relates to the technical field of medical instruments and comprises a painless bolt pushing device shell, a push rod is arranged in the painless bolt pushing device shell, a piston is fixedly mounted at the bottom of the push rod, a handle is fixedly mounted at the top of the push rod, and a handle is fixedly mounted at the bottom of the handle. An auxiliary extension is fixedly installed on the upper portion of the outer surface of the painless bolt pushing device shell, a lining is fixedly installed in the painless bolt pushing device shell, a suppository customized to be particularly long and thin is placed in the lining, and a thin film is arranged at the bottom of the painless bolt pushing device shell. The outer surface of the shell of the painless suppository pusher is subjected to super-smooth treatment, the suppository customized to be particularly slender is placed in the lining, the painless suppository pusher can be used for rectal administration after an anorectal small operation similar to haemorrhoids, and the problems that due to the fact that fingers are too thick, the suppository is slippery when a haemorrhoids suppository is plugged, and the suppository is not prone to being plugged by a patient repeatedly are solved.

The invention relates to a suppository vacuum emulsification system, and relates to the technical field of suppository processing, the suppository vacuum emulsification system comprises a base table and a processing table, the base table is vertically provided with a first premixing tank and a second premixing tank, and the lower parts of the first premixing tank and the second premixing tank are respectively provided with a first output pipe and a second output pipe; a configuration tank main body is vertically mounted on the treatment table; the other end of the first output pipe and the other end of the second output pipe are communicated with the upper part of the configuration tank main body, the bottom of the configuration tank main body is connected with a discharging pipe, and a temperature control assembly for controlling the temperature of the configuration tank main body and a protective cover mounted outside the temperature control assembly are arranged above the treatment table. The first output pipe, the second output pipe and the discharging pipe are each sleeved with a heat preservation pipe. According to the device, the first output pipe, the second output pipe and the discharging pipe are all sleeved with the heat preservation pipes, and by means of the design, the temperature stability of materials in the feeding, discharging and configuration processes can be effectively maintained.

The invention discloses a shaping device for suppository preparation and a using method, and relates to the technical field of suppository preparation.The shaping device comprises a mounting frame, a lower mold is fixedly connected to the bottom end of the inner side of the mounting frame, an upper mold is arranged on the upper portion of the lower mold, and a circulating water tank is fixedly connected to the upper end of the mounting frame; a water circulating unit is arranged on the rear side of the circulating water tank, a downward pressing unit is fixedly connected to the upper end of the inner side of the mounting frame, connecting units are fixedly arranged at the four corners of the bottom of the downward pressing unit, and the bottom of the water circulating unit is arranged on the inner side of the lower mold. The water circulation unit realizes uniform cooling, can stably control the circulating water temperature, prevents the temperature difference of different areas of the mold caused by water temperature fluctuation, enables suppositories at all positions in the mold to be solidified in a uniform cooling environment, reduces the defects of surface cracking and uneven hardness, and guarantees the quality consistency of the suppositories in the same batch.

Formulations comprising hydrocortisone are disclosed in a suppository for methods of treating ulcerative colitis and other gastrointestinal diseases and disorders. Administering a single hydrocortisone suppository once a day achieves remission or reduction of a symptom, optionally followed by a period of time in which the dosage is reduced.

1. The name of the design product: a dosing device. 2. The use of the design product: for pushing a suppository into a patient's vagina. 3. The design points of the design product: in shape. 4. The picture or photo that best shows the design points: perspective view 2.

The invention provides an enema nano suspension system for treating ulcerative colitis, which is prepared by taking indigo blue and indirubin as active components, adding a space stabilizer and a potential stabilizer and adopting a wet medium grinding method. The invention also provides an enema nano-foam system for treating ulcerative colitis. The enema nano-foam system comprises the drug-containing foam base liquid and the propellant. Aiming at the problems of poor solubility and permeability of indigo blue and indirubin, auxiliary materials are combined with a ball milling technology, and indigo blue and indirubin are subjected to surface modification and nanocrystallization, so that the solubility and permeability of indigo blue and indirubin are improved, the absorption of inflammatory cells to drugs is enhanced, and the bioavailability of indigo blue and indirubin is improved. The problems that conventional dosage forms such as traditional Chinese medicine rectal administration enema liquid and suppositories are prone to leakage, strong in foreign body sensation, limited in medicine distribution area and difficult to reach deeper ulcer lesions in intestines are solved, and the vacancy that at present, no convenient and effective enema treatment is available for ulcerative colitis is made up.

The utility model relates to the technical field of suppository medicine, in particular to boxed suppository medicine conveying equipment which comprises a shell, a bearing assembly and a cooling assembly, a conveying belt is arranged in the shell, the bearing assembly is arranged on the outer surface of the conveying belt, a positioning assembly is arranged at the top in the shell, and the cooling assembly is arranged in the shell. A cooling assembly is arranged at the top of the shell; the bearing assembly comprises a material receiving plate, grooves are formed in the surfaces of the two sides of the material receiving plate, supporting plates are rotationally connected into the grooves, rotating shafts are connected to the tops and the bottoms of the supporting plates through bolts, and the supporting plates are rotationally connected with the grooves through the rotating shafts. By additionally arranging the auxiliary bearing material supporting mechanism, the stability of the medicine in the conveying process is improved in the modes of overturning, positioning, buffering and supporting, and therefore the using effect is improved.

Formulations comprising hydrocortisone are disclosed in a suppository for methods of treating ulcerative colitis and other gastrointestinal diseases and disorders. Administering a single hydrocortisone suppository once a day achieves remission or reduction of a symptom, optionally followed by a period of time in which the dosage is reduced.