A screening kit for intractable epilepsy

Abstract

The invention discloses a screening reagent box for intractable epilepsy. The screening reagent box for the intractable epilepsy comprises an optional reagent used for detecting the expression level of micro RNA-153. The invention further discloses an application of the optional reagent used for detecting the expression level of the micro RNA-153 in preparing a reagent used for screening the intractable epilepsy. According to the reagent box, the expression level of the micro RNA-153 is detected, the risk of suffering from the intractable epilepsy for crowds to be examined can be judged, the reagent box can be used for auxiliary diagnosis of clinical intractable epilepsy, an effective base is provided for a patient to take relevant treatment measures or decisions, and a good clinical application prospect is achieved.

Description

technical field [0001] The invention relates to a screening kit for refractory epilepsy. Background technique [0002] Intractable epilepsy, also known as intractable epilepsy, usually refers to no progressive disease or space-occupying lesions of the central nervous system, but clinically protracted, after more than 2 years of regular antiepileptic treatment, trial of main antiepileptic drugs alone or in combination, reaching Refractory epilepsy can only be determined when the patient can tolerate the maximum dose, the blood drug concentration reaches the effective range, and the seizures cannot be controlled and daily life is affected. Refractory epilepsy accounts for about 20% to 30% of epilepsy patients. [0003] There are many causes of intractable epilepsy, most of which have brain lesions, such as hippocampal sclerosis, traumatic brain injury, tumor, tuberous sclerosis, and congenital dysplasia, etc. The influencing factors of intractable epilepsy include: ① Onset wi...

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Problems solved by technology

[0002] Refractory epilepsy, also known as intractable epilepsy, usually refers to no progressive disease or space-occupying lesions of the central nervous system, but clinically protracted, after more than 2 years of regular antiepileptic treatment, trial of main antiepileptic drugs alone or in combination, reaching Refractory epilepsy can only be determined when the patient can tolerate the maximum dose and the blood drug concentration reaches the effective range, but the seizures cannot be controlled and daily life is affected.

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