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Application of a traditional Chinese medicine composition in preparation of medicine for treating radiation-induced lung injury

A radioactive lung injury and composition technology, which is applied in the directions of drug combinations, active ingredients of hydroxy compounds, and pharmaceutical formulations, can solve problems such as the application of undisclosed traditional Chinese medicine compositions, and achieve significant curative effects, relieve symptoms, and eliminate pathogenic effects.

Active Publication Date: 2020-07-21
BEIJING YILING PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The above-mentioned patent does not disclose the application of the traditional Chinese medicine composition in the preparation and treatment of radiation-induced lung injury

Method used

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  • Application of a traditional Chinese medicine composition in preparation of medicine for treating radiation-induced lung injury
  • Application of a traditional Chinese medicine composition in preparation of medicine for treating radiation-induced lung injury
  • Application of a traditional Chinese medicine composition in preparation of medicine for treating radiation-induced lung injury

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0072] prescription:

[0073] Forsythia 255g Honeysuckle 255g Radix Radix 255g Rhubarb 51g

[0074] Patchouli 85g Mianma Guanzhong 255g Rhodiola 85g Menthol 7.5g

[0075] 85 grams of roasted ephedra, 85 grams of fried bitter almonds, 255 grams of Houttuynia cordata

[0076] Licorice 85g Gypsum 255g.

[0077] Preparation:

[0078] (1) Weigh Chinese herbal medicines according to the above prescription, and select them;

[0079] (2) Patchouli is broken, add 6 times the amount of water to extract the volatile oil, the oil extraction time is 4 hours, collect the volatile oil, and set aside; after the extract is filtered, the residue is discarded, and the filtrate is set aside;

[0080] (3) Forsythia, Sun-roasted Ephedra, Houttuynia cordata, and rhubarb were extracted twice with 8 times the amount of 70% ethanol, the first time was 2 hours, the second time was 1.5 hours, the extracts were combined and filtered, the ethanol was recovered, and the filtrate was used for later use; ...

Embodiment 2

[0086] prescription:

[0087] Forsythia 200g Honeysuckle 300g Radix Radix 200g Rhubarb 60g

[0088] Patchouli 60g Mianma Guanzhong 300g Rhodiola 60g Menthol 9g

[0089] 60 grams of roasted ephedra, 100 grams of fried bitter almonds, 200 grams of Houttuynia cordata

[0090] 100 grams of licorice and 200 grams of gypsum.

[0091] Preparation:

[0092] (1) Weigh Chinese herbal medicines according to the above prescription, and select them;

[0093] (2) Patchouli is broken, add 5 times the amount of water to extract the volatile oil, the oil extraction time is 4 hours, collect the volatile oil, and set aside; after the extract is filtered, the residue is discarded, and the filtrate is set aside;

[0094] (3) Forsythia, Sun-roasted Ephedra, Houttuynia cordata, and rhubarb were extracted twice with 6 times the amount of 50% ethanol, the first time was 1 hour, and the second time was 2.5 hours, the extracts were combined and filtered, the ethanol was recovered, and the filtrate w...

Embodiment 3

[0100] prescription:

[0101] Forsythia 300g Honeysuckle 200g Radix Radix 300g Rhubarb 40g

[0102] Patchouli 100g Mianma Guanzhong 200g Rhodiola 100g Menthol 5g

[0103] 100 grams of roasted ephedra, 60 grams of fried bitter almonds, 300 grams of Houttuynia cordata

[0104] 60 grams of licorice and 300 grams of gypsum.

[0105] Preparation:

[0106] (1) Weigh Chinese herbal medicines according to the above prescription, and select them;

[0107] (2) Patchouli is broken, add 8 times the amount of water to extract the volatile oil, the oil extraction time is 4 hours, collect the volatile oil, and set aside; after the extract is filtered, the residue is discarded, and the filtrate is set aside;

[0108] (3) Forsythia, Sun-burned Ephedra, Houttuynia cordata, and rhubarb were extracted twice with 10 times the amount of 90% ethanol, the first time was 3 hours, and the second time was 2.5 hours, the extracts were combined and filtered, the ethanol was recovered, and the filtrate...

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Abstract

The invention discloses an application of a traditional Chinese medicine composition in preparing a medicine for treating radiation-induced pulmonary injury. The traditional Chinese medicine composition is mainly composed of fructus forsythiae, honeysuckle flowers, isatis root, rheum officinale, pogostemon cablin, rhizoma dryopteris crassirhizomae and rhodiola rosea, has the integral regulation advantages of compound traditional Chinese medicines, can eliminate pathogenic factors, relieve the symptoms, and adjust immunity, and has a remarkable curative effect for treating radiation-induced pulmonary injury proved by the clinical test.

Description

technical field [0001] The invention relates to the application of a traditional Chinese medicine composition in the preparation of medicines for treating radiation-induced lung injury, and belongs to the field of Chinese herbal medicines. Background technique [0002] Radiation lung injury (radio-pulmonary lesion) is a complication caused by radiation therapy for malignant tumors of the chest. The common clinical manifestations are: the medical history of thoracic malignant tumors receiving radiation therapy and related respiratory symptoms. Symptoms generally appear 4 to 16 weeks after the start of radiation therapy, most of which occur within 2 to 4 weeks after the end of radiation therapy, and a few occur in the It can also occur within half a year after the end of radiotherapy, mainly due to dry cough, less sputum, dysphagia, chest tightness, chest pain, severe cases of dyspnea, low-grade fever, normal blood white blood cells, antibacterial treatment is ineffective, and...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/78A61P11/00A61K33/06A61K31/045
Inventor 魏聪贾振华常丽萍赵军红
Owner BEIJING YILING PHARMA
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