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Anti-allergy and anti-pruritus composite plant extract, and preparation method and application thereof

A technology for plant extracts and extracts, which is applied in the directions of plant raw materials, plant/algae/fungus/moss components, drug combinations, etc., can solve the problems of high cost, strong odor, large side effects, etc. The effect of anti-itching effect

Active Publication Date: 2015-12-02
广州钤诺生物科技有限公司 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] In the prior art, most of the anti-allergic and / or antipruritic products are hormone products, which are highly dependent and have relatively large side effects
Although there are some natural plant products, they are dark in color, strong in smell, unsatisfactory in anti-allergy and anti-itching effect, and high in cost

Method used

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  • Anti-allergy and anti-pruritus composite plant extract, and preparation method and application thereof
  • Anti-allergy and anti-pruritus composite plant extract, and preparation method and application thereof
  • Anti-allergy and anti-pruritus composite plant extract, and preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0040] Preparation of Example 1 Biotechnology Kangmin Zhiyang Recipe 1

[0041] Take 45kg of fresh Panax notoginseng root, add 100kg of water, grind it into a paste of 400-800 mesh through a colloid mill, and ultrasonically treat it for 20 minutes under the condition of 25,000 Hz; take 35kg of honeysuckle and 20kg of chamomile, and grind it into 10-60 mesh particles.

[0042] Mix the above three treated medicinal materials evenly, add 0.1 kg of cellulase and 0.5 kg of maltase, and mix evenly, and perform enzymatic hydrolysis at 35°C for 5 hours to obtain an enzymatic hydrolyzate. During enzymatic hydrolysis, control the content of The amount of water is 50-70%.

[0043] Extraction solvent: prepare 80% ethanol aqueous solution (V / V) by volume.

[0044] The above enzymatic hydrolysis mixture was extracted with 700L of extraction solvent at 70°C for 3 hours, filtered, the ethanol in the filtrate was evaporated to dryness, concentrated to 10-15kg, 75kg of propylene glycol was ad...

Embodiment 2

[0045] Preparation of Example 2 Biotechnology Kangmin Zhiyang Recipe 2

[0046] Take 65kg of fresh Panax notoginseng root, add 150kg of water, grind it into a paste of 400-800 mesh through a colloid mill, and ultrasonically treat it for 35 minutes under the condition of 30,000 Hz; take 10kg of honeysuckle and 25kg of chamomile, and grind it into 10-60 mesh particles.

[0047] Mix the above three treated medicinal materials evenly, add 1.2 kg of cellulase and 0.3 kg of maltase, mix evenly, and perform enzymatic hydrolysis at 45° C. for 8 hours.

[0048] Extraction solvent: prepare 85% ethanol aqueous solution (V / V) with volume concentration.

[0049] The above enzymatic hydrolysis mixture was extracted with 800 L of extraction solvent at 70°C for 3 hours, filtered, the ethanol in the filtrate was evaporated to dryness, concentrated to 10-15 kg, 75 kg of propylene glycol was added, and water was added to make up to 100 kg, and the biotechnology anti-allergic Antipruritic formula...

Embodiment 3

[0051] The preparation method of the anti-allergic and antipruritic compound plant extract provided in this example is prepared by the following method:

[0052] (1) Take Panax notoginseng, add water to the panax notoginseng, grind it into a paste, and perform ultrasonic cell wall breaking treatment, set aside, take honeysuckle and chamomile and pulverize it for use;

[0053] (2) Mix the treated Panax notoginseng, honeysuckle and chamomile, add cellulase and maltase, and enzymolyze to obtain an enzymatic hydrolyzate;

[0054] (3) Put the enzymatic hydrolyzate in an extraction solvent to extract and obtain an extract, and then process the extract to obtain an anti-allergic and antipruritic compound plant extract.

[0055] In the preparation method of the above-mentioned antiallergic and antipruritic compound plant extract:

[0056] In the step (1), the mass ratio of Panax notoginseng, honeysuckle and chamomile is 10:80:10.

[0057] In step (1), grind into a paste of 400-800 m...

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Abstract

The invention discloses a preparation method of an anti-allergy and anti-pruritus composite plant extract. The preparation method comprises the following steps of (1) taking panax notoginseng, adding water in the panax notoginseng, performing ultrasonic cell wall-breaking treatment for subsequent use, and pulverizing honeysuckle and chamomile for subsequent use; (2) uniformly mixing the panax notoginseng, the honeysuckle and the chamomile which are pretreated in the step (1), and adding cellulase and maltase to carry out enzymolysis so as to obtain enzymatic hydrolysate; and (3) extracting the enzymatic hydrolysate by using extracting solvent to obtain extracting solution, and performing follow-up treatment on the extracting solution to obtain the anti-allergy and anti-pruritus composite plant extract. The invention also discloses the anti-allergy and anti-pruritus composite plant extract prepared by the method. The composite plant extract is safe and non-irritant, and can be used for preparing anti-allergy and anti-pruritus medicines or cosmetics. The anti-allergy and anti-pruritus effect of the anti-allergy and anti-pruritus composite plant extract is obviously higher than that of a plant extract prepared by a traditional method.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to an anti-allergic and antipruritic compound plant extract and a preparation method and application thereof. Background technique [0002] With the development of society and the continuous improvement of people's living standards, the social pressure from work and life is also increasing. Various diseases plague people, especially allergies, itching and other diseases. , making the majority of people miserable. There is also a growing demand for safe and effective natural anti-allergy and / or anti-itch products. [0003] Most of the anti-allergic and / or antipruritic products in the prior art are hormone products, which are highly dependent and have relatively large side effects. Although there are also some natural plant products, they are dark in color, strong in smell, unsatisfactory in anti-allergy and anti-itching effect, and high in cost. ...

Claims

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Application Information

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IPC IPC(8): A61K36/355A61K8/97A61P37/08A61P17/04A61Q19/00
Inventor 张伟李雷敢小双陈建明
Owner 广州钤诺生物科技有限公司
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