Touch-screen multifunctional non-human primate animal cognitive-function testing method

A primate and cognitive function technology, applied in the field of cognitive ability testing of non-human primates, can solve the problem of not preventing rhesus monkeys from accidentally touching the touch screen, unable to adjust the position of the water supply system, and difficult to prepare food for feeding and other problems, to achieve the effects of reliable test results, low cost of purchase and use, and easy installation

Active Publication Date: 2016-05-04
KUNMING INST OF ZOOLOGY CHINESE ACAD OF SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The disadvantages of this system and testing method are:
[0005] 1. Its hardware is only a box-shaped device with a touch screen, and it must be equipped with a corresponding cage when used; in addition, it is heavy (about 25kg), and it needs to be equipped with a corresponding lifting device to adjust its distance and height from the monkey cage. platform
[0006] 2. Rewards are given to macaques by feeding. The given food needs to be specially processed into biscuit particles with a certain shape and hardness, otherwise the automatic feeding system will break down, and the production of feeding food is difficult and expensive ( The price is about 2800 RMB / kg)
[0007] 3. Lack of some practical functions, for example, the position of the water supply system cannot be adjusted, there is no design to prevent macaques from accidentally touching the touch screen, and there is no camera to monitor the tested animals, etc.
[0008] 4. The price is expensive, 150,000 to 200,000 RMB

Method used

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  • Touch-screen multifunctional non-human primate animal cognitive-function testing method
  • Touch-screen multifunctional non-human primate animal cognitive-function testing method
  • Touch-screen multifunctional non-human primate animal cognitive-function testing method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] Example 1: see Figure 1 ~ Figure 4 . The apparatus used includes a test cage 1 and a transfer cage 2 .

[0029] The bottom of the test cage 1 is provided with a longitudinal rear façade track (not shown in the figure), and the stainless steel plate rear façade 3 that can move back and forth and lock the position is installed on the rear façade rail, and a square opening is opened on the rear façade A 17-inch infrared induction touch screen 4 electrically connected to the computer is fastened in the mouth, and the touch surface of the touch screen 4 faces the inside of the test cage 1. The top surface of the test cage 1 is provided with a plexiglass observation window 5 and a camera frame 6 that allows the surveillance camera (not shown) to move. The water supply device includes a stepping motor as the power of the syringe push rod, an electronic controller of the stepping motor, a water inlet pipe 18, a flexible pipe connecting the water nozzle 7 and the outlet of th...

Embodiment 2

[0030] Example 2: see Figure 5 and Image 6 . A base plate 25 parallel to the touch screen 24 is fastened to the lower front of the touch screen 24 in the test cage 23 in the device used, and the bottom of the base plate 25 is fastened to a screw seat 26, and a screw mandrel 27 that can vertically move up and down is connected with the Screw seat 26 is screwed. A rack stand 28 is fastened to the upper end of the screw mandrel 27 . The rack pedestal 28 is provided with a pinion 29 ( Figure 5 not shown), and fasten a rack groove 30 perpendicular to the touch screen 24 above the pinion 29 on the rack pedestal 28, and place a front and rear moving rack meshed with the pinion 29 in the rack groove 30 31. On the tooth bar 31 fasten a water supply bar 32 ( Image 6 not shown in). The upper end of the water supply rod 32 is fastened with a water supply nozzle 33 provided with a water outlet hole (not shown). Both the inside of the rack 31 and the inside of the water supply r...

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Abstract

The invention discloses a touch-screen multifunctional non-human primate animal cognitive-function testing method and belongs to the technical field of animal experiment devices. A touch screen capable of moving back and forth and a water supply nozzle capable of moving vertically are arranged in a testing cage. A monkey raised in a living cage is transferred to the testing cage through a transfer cage, the condition of the monkey in the transfer process is observed through an observation window of the transfer cage, a transfer cage door is in butt joint with a testing cage door after in-place transfer is completed, the transfer cage door and the testing cage door are pulled open, the testing cage door is closed through insertion after the monkey enters the testing cage, the monkey is enabled to complete a task at a natural sitting posture and obtain a drinking water award, an injector containing drinking water or fruit juice is accurately pushed through computer control, and the drinking water or fruit juice award is quantitatively given to the monkey. After the monkey correctly completes a screen touching task, the monkey drinks clear water or fruit juice from the water supply nozzle, and the quantitative relation formula of the height Y from the water supply nozzle to the bottom face of the testing cage and the distance X from the water supply nozzle to the touch face of the touch screen is determined as Y=0.4661X + (26-30), and measurement unit is millimeter.

Description

technical field [0001] The invention belongs to the technical field of animal experiment equipment, and in particular relates to a method for testing the cognitive ability of non-human primates. Background technique [0002] In the field of neurobiology, it is often necessary to conduct behavioral tests on experimental animals. By allowing experimental animals to complete a certain behavioral paradigm to evaluate their cognitive abilities and brain functions, and then reveal the rules of brain activity. Non-human primates, such as rhesus monkeys, as a high-level experimental animal, have advanced and complex nervous systems and can complete a variety of complex behavioral tasks; Cognitive function assessment is a very important research method in neurobiology. [0003] Based on neuropsychology, predecessors have developed a set of behavioral paradigms for evaluating the advanced brain functions of macaques. Combined with food rewards, macaques are allowed to complete a seri...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B5/00A01K15/02
CPCA01K15/027A61B5/4064A61B5/4076
Inventor 吴诗昊杨上川胡英周张琳恒谭恒吴晶张玉华胡新天
Owner KUNMING INST OF ZOOLOGY CHINESE ACAD OF SCI
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