Compound Chinese herbal medicine for inhibiting and killing aeromonas hydrophila as well as preparation method and application of compound Chinese herbal medicine

A technology of Aeromonas hydrophila and Chinese herbal medicine, applied in the field of freshwater aquaculture, can solve the problems of loss of aquaculture industry, loss of Aeromonas hydrophila disease, frequent occurrence of diseases of aquaculture animals, etc.

Inactive Publication Date: 2016-06-29
SOUTHWEST UNIVERSITY
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Problems solved by technology

[0004] The object of the present invention is to provide a compound Chinese herbal medicine for inhibiting and killing Aeromonas hydrophila and its preparation method and application. Massive breeding, frequent occurrence of aquaculture animal diseases, heavy losses in the aquaculture industry, and diseases caused by Aeromonas hydrophila also caused a lot of losses

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  • Compound Chinese herbal medicine for inhibiting and killing aeromonas hydrophila as well as preparation method and application of compound Chinese herbal medicine
  • Compound Chinese herbal medicine for inhibiting and killing aeromonas hydrophila as well as preparation method and application of compound Chinese herbal medicine

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Embodiment Construction

[0015] In order to make the object, technical solution and advantages of the present invention more clear, the present invention will be further described in detail below in conjunction with the examples. It should be understood that the specific embodiments described here are only used to explain the present invention, not to limit the present invention.

[0016] The present invention takes Aeromonas hydrophila as the research object, and preliminarily screens out 7 kinds of Chinese herbal medicines such as Chinese gallbladder, Burnet, rhubarb, Scutellaria baicalensis, Coptis chinensis, licorice and betel nut through the agar diffusion method from 30 kinds of Chinese herbal medicines; The t-value method shows that the main drug is Gallnut; the auxiliary drugs are identified as Burnet and Rhubarb through the combined effect of the auxiliary drugs; the dose ratio of Gallnut, Burnet and Rhubarb is 5:2:1 through dose analysis .

[0017] Taking (136.33±15.94)g heterogeneous gibel...

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Abstract

The invention discloses a compound Chinese herbal medicine for inhibiting and killing aeromonas hydrophila as well as a preparation method and application of the compound Chinese herbal medicine. The compound Chinese herbal medicine consists of gallnut, sanguisorba officinalis root and rheum officinale, wherein the weight ratio of the gallnut, to the sanguisorba officinalis root to the rheum officinale is at 5 to 2 to 1. Meanwhile, the invention discloses a preparation method and application of the compound Chinese herbal medicine for inhibiting and killing aeromonas hydrophila. The compound Chinese herbal medicine disclosed by the invention achieves the reasonable development and utilization of compound Chinese herbal medicine resources; in culture of aquatic animals, the compound Chinese herbal medicine has a great significance in guaranteeing animal nutrition, promoting growth of the animals and improving the disease preventing and disease resisting capacities of the animals, and meanwhile the compound Chinese herbal medicine is also in line with the requirements of aquaculture in sustainable development; in order to reduce loss of the aquaculture industry caused by diseases, a medicine, which is relatively strong in effect and low in toxic and side effects, becomes particularly important in the prevention and control of the diseases; and by taking the aeromonas hydrophila as a research object, the compound Chinese herbal medicine, which is relatively good in antibacterial effect, is screened out, so that the invention provides reference for prevention and control practice of diseases in aquatic animals and fish bacterial diseases caused by the aeromonas hydrophila.

Description

technical field [0001] The invention belongs to the technical field of freshwater aquaculture, and in particular relates to a compound Chinese herbal medicine for inhibiting Aeromonas hydrophila and its preparation method and application. Background technique [0002] Aeromonas hydrophila (Aeromonas hydrophila) belongs to Vibriaceae and Aeromonas genus. It is a rod-shaped, Gram-negative, dynamic group of Aeromonas. Anaerobic, non-spore-forming, non-capsular. The physiological and biochemical characteristics are: V test, oxidase, nitrate reduction, gelatin liquefaction, indole test, arginine double hydrolysis, lysine decarboxylase positive, can ferment glucose to produce acid and gas. The growth pH is 5.5-9.0, and the optimum growth temperature is 28°C. It has a certain growth ability at low temperature, and the lowest growth temperature reaches -0.1°C. It is widely found in fresh water, sea water, rivers, sewage, silt, soil and human feces; it also exists in various foods,...

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/739A61P31/04A61K35/64
CPCA61K35/63A61K36/708A61K36/739A61K2236/331A61K2236/39A61K2236/51A61K2300/00
Inventor 郑永华唐洪玉胡文达
Owner SOUTHWEST UNIVERSITY
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