Qi stagnation stomachache particle anti-ulcer quality control method based on dose-effect color card

Abstract

The invention relates to a qi stagnation stomachache particle anti-ulcer quality control method based on a dose-effect color card. According to the quality control method, by means of establishment of a qi stagnation stomachache particle fingerprint spectrum and efficacy evaluation of the qi stagnation stomachache particle anti-ulcer effect, the quality and efficacy relevance of qi stagnation stomachache particles is evaluated, a dose-effect relation equation is established, the qi stagnation stomachache particle anti-ulcer action dose-effect color card is successfully established, and thus it is achieved that by detecting the relative peak area of specific ingredients in the qi stagnation stomachache particles, the anti-ulcer efficacy of the qi stagnation stomachache particles can be visually reflected in the color card mode, and the quality control method can be used for evaluating the degree of the anti-ulcer effect performed by the qi stagnation stomachache particles and the quality of the qi stagnation stomachache particle.

Description

technical field [0001] The invention relates to a medicine quality control method, in particular to a quality control method of Qizhiweitong granule anti-ulcer by using "color card" software to visually reflect the dose-effect relationship. Background technique [0002] The quality control of traditional Chinese medicine compound preparations has always been a difficult and hot issue that plagues the quality monitoring of traditional Chinese medicine preparations and their entry into the international market, and is also an important foundation and key to the modernization of traditional Chinese medicine. my country's quality standards for compound preparations of traditional Chinese medicine have gone through a process from scratch, from simplicity to gradual improvement, and are still being explored. In the 2005 edition of "The Pharmacopoeia of the People's Republic of China", thin-layer chromatography is widely used in the identification of compound preparations; high-per...

AI Technical Summary

Problems solved by technology

At present, a lot of research has been done on the quality control of Qizhi Weitong Granules, and the applicant has carried out patent protection for the quality control method of Qizhi Weitong Granules (full-time multi-wavelength fusion fingerprint quality control method for Qizhi Weitong Granules , Patent No. 201210223306.4), however, the simple quality control method only regulates its chemical composition, and it is unknown whether these chemical compositions are related to their efficacy. Ulcer efficacy, established a quality control method of Qizhi Weitong Granules anti-ulcer based on the "dose-effect color card", so as to truly control the quality of active ingredients

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