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Degradable medical implant metal material and preparation method thereof

An alloy material, biomedical technology, applied in the field of medical metal material preparation, can solve problems such as rare earth element hazards, and achieve the effects of reducing oxide impurities or element burnout, excellent mechanical properties, and good mechanical properties

Active Publication Date: 2016-10-05
LEPU MEDICAL TECH (BEIJING) CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the alloy system may have the risk of introducing harmful trace elements (such as non-nutrient elements Si, Li, Ag, Sn and rare earth elements, etc.), especially rare earth elements are often considered as unfavorable elements that can cause harmful effects on the human body ( Toxicological Sciences, 1997, 37(2): 106-116.)

Method used

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  • Degradable medical implant metal material and preparation method thereof
  • Degradable medical implant metal material and preparation method thereof
  • Degradable medical implant metal material and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1-4

[0033] Embodiment 1-4 Zinc-based alloy material

[0034] The formula is as follows:

[0035]

Embodiment 5

[0036] The preparation method of embodiment 5 as-cast zinc-based alloy material

[0037] The preparation process is as follows:

[0038] Each raw material of alloy material described in embodiment 1 is mixed, then in CO 2 Melt at 500°C for 2 hours under atmosphere protection, mix well during this period, keep it standing for 20 minutes, cool to 450°C, and then pour the molten material into a mold preheated to 200°C to obtain a zinc-based alloy ingot.

[0039] The as-cast structure of the obtained zinc-based alloy ingot is as follows: figure 1 As shown, the as-cast zinc-based alloy structure is relatively coarse, with dendrites and eutectic structures.

Embodiment 6-8

[0040] The preparation method of embodiment 6-8 as-cast zinc-based alloy material

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Abstract

The invention relates to a biological medical degradable zinc-based alloy. The biological medical degradable zinc-based alloy is characterized in that a zinc alloy system is composed of Zn, Mg, Ca and Mn and comprises, by mass, 0 to 1.5% of Mg, 0 to 0.5% of Ca and 0 to 0.2% of Mn, with the balance being Zn, wherein Mg is not equal to 0. The zinc-based alloy prepared in the invention avoids introduction of unfavorable elements, has good mechanical properties, excellent corrosion resistance and strong corrosion failure controllability, and can meet requirements for biological safety and comprehensive mechanical properties of a biomaterial in the field of medical instruments.

Description

technical field [0001] The invention relates to a biomedical metal material and a preparation method thereof, in particular to a fully degradable zinc-based alloy in a living body and a preparation method thereof, belonging to the technical field of medical metal material preparation. Background technique [0002] In recent years, magnesium alloys and iron alloys, as a new generation of revolutionary metal medical materials with biodegradable properties, have received special attention from researchers. This kind of material cleverly utilizes the active chemical properties of metals, which can show relatively corrosive characteristics in body fluids, so as to realize the clinical purpose of implants degrading and eventually disappearing without causing toxic side effects. However, the current degradable medical metal materials have certain defects. Degradable metals represented by magnesium-based alloys generally degrade completely in the human body within a few days, and c...

Claims

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Application Information

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IPC IPC(8): C22C18/00C22F1/16
Inventor 刘西伟杨映红潘腾飞武楠崔凯蒲忠杰
Owner LEPU MEDICAL TECH (BEIJING) CO LTD
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