Nerve graft capable of guiding nerve tracts to be regenerated accurately

Abstract

The invention relates to a nerve graft capable of guiding nerve tracts to be regenerated accurately. The nerve graft comprises a plurality of nerve guide wires and an outer sleeve, and is prepared from a material with good nerve biocompatibility. The guide wires are inserted into the nerve tracts corresponding to two broken ends of a nerve trunk, so that a function of accurately guiding the nerve tracts to grow in an orientated manner is fulfilled, meanwhile, the two broken ends of the nerve trunk are fixedly connected through the outer sleeve, and the circumstance that the guide wires slip due to pulling of the nerve trunk in a moving process of limbs is prevented. The whole nerve graft is simple in structure, and is convenient and speedy in an implanting process, and meanwhile, the effect of nerve regeneration and repair can be improved.

Description

technical field [0001] The invention belongs to the field of medical materials, in particular to a nerve graft, in particular to a nerve graft capable of guiding precise regeneration of nerve bundles. Background technique [0002] In the nervous system, some nerve fibers with basically the same function and starting and ending points gather together to form a bundle structure called nerve bundle, also called fiber bundle or conduction bundle. Regardless of central or peripheral nerves, the conduction of nerve signals depends on several nerve bundles passing through them. At present, in the aspect of nerve transection and defect repair, grafts with good biocompatibility are gradually increasing, especially the emergence of multi-channel longitudinal catheters manufactured according to the principle of tissue engineering and catheter materials loaded with nerve guiding factors can guide the directional growth of nerve fibers. . However, the existing graft materials are gener...

AI Technical Summary

Problems solved by technology

However, the existing graft materials are generally connected to the stumps of the host’s nerves by butt sutures, which can easily deform the stump tissue under pressure and hinder the passage of regenerated nerve fibers; There will be a certain displacement in the center of the nerve, which cannot be simulated by general grafting materials. For the repair of nerve defects, especially long-segment nerve defects, there is a high mismatch rate of nerve fibers, which greatly reduces the repair effect.

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