The invention provides a comprehensive tunnel drainage, precipitation and pressure reduction construction method, relates to an in-tunnel drainage, ground precipitation and comprehensive pressure reduction construction method for a water and mud burst segment of a tertiary system sand shale tunnel and is mainly designed to solve the problems that an existing tunnel is prone to deformation, collapse and even water burst and mud burst in the tertiary system sand shale construction process. Ground precipitation wells are drilled at the positions, eight meters away from the side lines on the two sides, of a ground-direction positive hole, a flat guide hole is formed near the ground-direction positive hole, a drainage hole is formed in the inclined upper direction of the ground-direction positive hole relative to the flat guide hole, tunnel substrate precipitation wells are drilled in both the substrate of the ground-direction positive hole and the substrate of the flat guide hole, a plurality of inclined drainage holes are formed above the inclined front portion of a vault of the ground-direction positive hole, a positive hole vertical drainage hole is formed above the vault of the ground-direction positive hole, and a flat guide hole vertical drainage hole is further formed above the vault of the flat guide hole. The comprehensive tunnel drainage, precipitation and pressure reduction construction method has the advantages that geological disasters such as collapse, deformation, water burst and mud burst are avoided, and tunnel construction safety can be guaranteed.