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Cooked pseudo-ginseng and preparation method thereof

A technology for cooked Panax notoginseng and Panax notoginseng is applied in the field of cooked Panax notoginseng and its preparation, and can solve the problems such as not being found to contain oleanolic acid type saponins and the like

Active Publication Date: 2016-11-23
四川仟源中药饮片有限公司 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The main active ingredient of Panax notoginseng is notoginseng saponin. So far, more than 60 kinds of monomeric saponins have been isolated from different parts of Panax notoginseng. Most of these monomeric saponins are dammarane 20(S)-protoginseng Alcohol type [20(S)-protopanaxadio1] and 20(S)-protopanaxatriol type [20(S)-peotopanaxatrio1], but no oleanolic acid type saponins were found

Method used

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  • Cooked pseudo-ginseng and preparation method thereof
  • Cooked pseudo-ginseng and preparation method thereof
  • Cooked pseudo-ginseng and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] The preparation of embodiment 1 cooked Panax notoginseng powder

[0021] Take 5kg of dry rhizome (cut) of raw Panax notoginseng, wash it with drinking water, add 5kg of drinking water to soak until thoroughly, wash thoroughly with drinking water to remove soil impurities, cut into 1mm pieces, put it in a pressure cooker at 118°C Steam for 3 hours, dry under reduced pressure at 50°C for 24 hours, and pulverize into fine powder to obtain 4.56 kg of cooked Panax notoginseng powder. The content of saponins in cooked Sanqi powder was determined by HPLC, and the results showed that Sanqi saponin R 1 0.38%, Ginsenoside Rg 1 1.78%, Ginsenoside Rb 1 2.53%, Ginsenoside 20(S)-Rh 1 0.63%, Ginsenoside 20(R)-Rh 1 0.34%, Ginsenoside Rd 0.56%, Ginsenoside Rk 3 0.51%, Ginsenoside Rh 4 1.58%, Ginsenoside 20(S)-Rg 3 0.44%, Ginsenoside 20(R)-Rg 3 0.24%, Ginsenoside Rk 1 0.26%, Ginsenoside Rg 5 1.11%.

Embodiment 2

[0022] The preparation of embodiment 2 cooked notoginseng tablets

[0023] Take 5kg of dry main root of raw Panax notoginseng, wash it with drinking water, add 2.5kg of drinking water to soak until thoroughly, wash thoroughly with drinking water to remove soil impurities, cut into 3mm thick slices, put it in a pressure cooker at a temperature of 116°C, Steam for 4 hours, and dry under normal pressure at 105°C for 8 hours to obtain 4.42 kg of cooked Panax notoginseng tablets. The content of saponins in cooked Sanqi powder was determined by HPLC, and the results showed that Sanqi saponin R 1 0.29%, Ginsenoside Rg 1 1.40%, Ginsenoside Rb 1 1.94%, Ginsenoside 20(S)-Rh 1 0.61%, Ginsenoside 20(R)-Rh 1 0.33%, Ginsenoside Rd 0.46%, Ginsenoside Rk 3 0.50%, Ginsenoside Rh 4 1.57%, Ginsenoside 20(S)-Rg 3 0.42%, Ginsenoside 20(R)-Rg 3 0.22%, Ginsenoside Rk 1 0.25%, Ginsenoside Rg 5 1.16%.

Embodiment 3

[0024] The preparation of embodiment 3 cooked Panax notoginseng

[0025] Take 5 kg of fresh Panax notoginseng main root, clean it, put it in a pressure cooker at a temperature of 121°C, steam for 2 hours, and dry at 100°C under normal pressure for 12 hours to obtain 4.67kg of cooked Panax notoginseng. The content of saponins in cooked Sanqi powder was determined by HPLC, and the results showed that Sanqi saponin R 1 0.21%, Ginsenoside Rg 1 0.78%, Ginsenoside Rb 1 2.18%, Ginsenoside 20(S)-Rh 1 0.71%, Ginsenoside 20(R)-Rh 1 0.12%, Ginsenoside Rd 0.06%, Ginsenoside Rk 3 0.39%, Ginsenoside Rh 4 1.61%, Ginsenoside 20(S)-Rg 3 0.17%, Ginsenoside 20(R)-Rg 3 0.08%, Ginsenoside Rk 1 0.25%, Ginsenoside Rg 5 0.65%.

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Abstract

The invention discloses cooked pseudo-ginseng. By weight, the total saponin content is 6.0-12.0%, and the sum of the content of the low-grade saponin in the transformation accounts for 40-90% of the total saponins of the cooked pseudo-ginseng. Inherent saponins in pseudo-ginseng contain ginsenoside R1, ginsenoside Rg1, and ginsenoside Rb1, the low-grade saponins generated by transformation contains ginsenoside 20 (S)-Rh1, ginsenoside 20 (R)-Rh1, ginsenoside Rd, ginsenoside Rk3, ginsenoside Rh4, ginsenoside 20 (S)-Rg3, ginsenoside 20(R)-Rg3, ginsenoside Rk1, and ginsenoside Rg5. The invention also discloses a preparation method of the cooked pseudo-ginseng. By precisely controlling the water addition, processing temperature and processing time, the cooked pseudo-ginseng having a certain saponin and the proportion thereof is obtained. The cooked pseudo-ginseng is rich in low-grade saponins that rarely exists in the dried pseudo-ginseng and can improve the immunity and the anti-tumor effect.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicines, and in particular relates to cooked notoginseng and a preparation method thereof. Background technique [0002] Panax notoginseng, alias: false ginseng, ginseng notoginseng, field notoginseng, mountain lacquer, notoginseng, Latin scientific name: Panaxnotoginseng (Burk.) F.H.Chen, is a perennial herb of Araliaceae ginseng, with short rhizomes and fleshy Root cylindrical, distributed in Yunnan, Guangxi, Jiangxi, Sichuan and other places. Panax notoginseng is mainly rich in components such as saponins, flavonoids, protein amino acids and non-protein amino acids, polysaccharides, proteins, sterols, inorganic substances, volatile oils and greases. The main active ingredient of Panax notoginseng is notoginseng saponin. So far, more than 60 kinds of monomeric saponins have been isolated from different parts of Panax notoginseng. Most of these monomeric saponins are dammarane 20(S)-protogin...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/258A61K31/704A61P37/04A61P35/00
Inventor 茅仁刚代向向吴献荣
Owner 四川仟源中药饮片有限公司
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