126 results about "Ginsenoside Rg1" patented technology

The invention discloses a method for large-scale production of rare ginsenoside Rk3. According to the invention, wild type beta-glucosidase derived from Sulfobus acidocaldarius is modified, so that the beta-glucosidase has efficient enzymatic activity of catalyzing the conversion of ginsenoside Rg1 into ginsenoside Rh1, and meanwhile, the heat-resistant and acid-resistant characteristics of the enzyme are retained, so that the ginsenoside Rg1 can be converted into ginsenoside Rk3 by adopting a one-pot method. The technology for large-scale production of ginsenoside Rk3 is obtained through optimization, and a foundation is laid for large-scale application of ginsenoside Rk3 in the market.

The invention discloses traditional Chinese medicine monomer self-assembled nanoparticles as well as a preparation method and application thereof, and relates to the technical field of pharmaceutical preparations. According to the prepared traditional Chinese medicine monomer self-assembled nanoparticles, namely ginsenoside Rg1-oleanolic acid self-assembled nanoparticles, the self-assembled structural characteristics of ginsenoside Rg1 are ingeniously utilized, the superficial area of the medicine can be effectively increased, the solubility of oleanolic acid can be improved, and therefore the bioavailability of oleanolic acid is effectively improved, and the anti-inflammatory effect of the oleanolic acid is further enhanced. And compared with a physical mixed medicine with the same dosage, the effect is more remarkable. Besides, the preparation method is simple and easy to implement, not only has the advantages of nanoscale drugs, but also realizes self-delivery of pure drugs without auxiliary materials, and greatly improves the delivery efficiency of the drugs.

The invention discloses an anti-neurodegeneration exosome composition as well as a preparation method and application thereof. The anti-neurodegeneration exosome composition is prepared from the following components in parts by mass: 5 to 25 parts of human exfoliated deciduous tooth stem cell exosome, 25 to 85 parts of plant-derived exosome-like nano-vesicles, 12 to 10 parts of ginsenoside Rg, 2 to 10 parts of curcumin and 10 to 20 parts of auxiliary materials. The anti-neurodegeneration exosome composition contains a large amount of cell factors, growth factors, miRNA, mRNAs and other components, is easy to fuse with cell membranes of intestinal epithelial cells, can selectively deliver bioactive substances to recipient cells through a blood-brain barrier, carries out information transmission among different cells, regulates signal transduction among the cells, and has a good anti-neurodegeneration effect. The effects of resisting oxidation, resisting inflammation, resisting aging and the like are achieved.

The invention discloses design and synthesis of a series of brain-targeted ginsenoside Rg1 derivatives and application of the brain-targeted ginsenoside Rg1 derivatives in treatment of Alzheimer's disease. According to the invention, ginsenoside Rg1 and polyethylene glycol with a specific chain length are covalently linked to successfully construct the derivative capable of enhancing the penetrating power of the blood-brain barrier. The series of derivatives provided by the invention not only solve the problems of poor brain targeting and insufficient stability of natural Rg1, but also can inhibit neuroinflammation by regulating and controlling an NLRP3 / caspase-1 signal channel in an LPS-induced neuroinflammation model, and finally, the learning and memory ability is remarkably improved. The product is simple and convenient in preparation process and good in biological safety, and a new candidate compound is provided for developing a new generation of Alzheimer disease treatment medicines.

The invention discloses application of notoginsenoside in preparation of a wound repairing medicine, and particularly discloses application of notoginsenoside in preparation of the wound repairing medicine. The notoginsenoside comprises ginsenoside Rb1, ginsenoside Re, ginsenoside Rg1 and notoginsenoside R1. The specific action mechanism of notoginsenoside in promoting wound healing is explored, and notoginsenoside is effectively applied to clinical practice, so that the current technical blank can be filled, and a new treatment way can be provided for wound repair, thereby benefiting the majority of patients.

The present invention relates to the technical field of determination of ingredients in Chinese patent medicines, and in particular to a method for detecting ginsenoside content and an application thereof. The present invention utilizes a multiple heart-cutting two-dimensional liquid chromatography tandem charged aerosol detector method to detect the content of ginsenosides including notoginsenoside R1, ginsenoside Rg1, ginsenoside Re, 24(R)-pseudoginsenoside F11, ginsenoside Rf, ginsenoside Ra2, ginsenoside Rb1, ginsenoside Rg2, ginsenoside Rh1, ginsenoside Rc, ginsenoside Ro, ginsenoside Rb2, ginsenoside Rb3, ginsenoside Rd, ginsenoside Rg3(S), and ginsenoside Rg3(R). The method has the advantages of accuracy, high sensitivity, and strong specificity, is suitable for determining the content of ginsenosides in different Chinese patent medicines containing Panax genus Chinese medicines, and can be used reliably, comprehensively, and accurately for quality control of ginsenosides in Chinese patent medicines containing Panax genus Chinese medicines.

The invention discloses a traditional Chinese medicine composition for treating chronic obstructive pulmonary disease as well as a preparation and application thereof, and belongs to the technical field of chronic obstructive pulmonary disease medicines. The traditional Chinese medicine composition consists of a qi tonifying component, a blood activating component and a phlegm reducing component, or consists of the qi tonifying component and the blood activating component, or consists of the qi tonifying component and the phlegm reducing component, wherein the qi-tonifying component is selected from any one or a combination of more of ginsenoside Rg1, ginsenoside Rb1, astragaloside and schizandrin; the blood activating component is selected from any one or combination of more of ligustrazine and ferulic acid; the phlegm reducing component is selected from any one or combination of more of glucosinolate and quercetin. The compatibility and combination of the medicines have obvious effects in the aspects of improving lung inflammatory response and inhibiting pathological remodeling of pulmonary blood vessels.

The invention discloses a compound donkey-hide gelatin pulp thin-layer chromatography fingerprint construction and combination evaluation analysis method, and belongs to the technical field of traditional Chinese medicine quality control. The compound colla corii asini pulp thin-layer chromatography is a thin-layer chromatography fingerprint spectrum of the compound colla corii asini pulp or an intermediate in a process preparation process; the construction of the thin-layer chromatography fingerprint spectrum is based on the color of a thin-layer chromatography sample strip image and the gray scale of spots, and a pixel-intensity matrix and a ratio shift value-gray scale matrix are formed to comprehensively reflect the thin-layer chromatography characteristics of the sample; according to the combined evaluation method of the thin-layer chromatography fingerprint spectrum, a method of combining machine learning with information entropy and entropy is adopted, ginsenoside Rg1, codonopsis pilosula alkynol and other components are screened and identified as key components influencing the compound donkey-hide gelatin pulp and transmission, and the method has the characteristics of accuracy and high efficiency, is wide in application prospect and can provide a thought for establishment of quality standards of traditional Chinese medicine compounds.

The invention discloses a preparation method of composite microspheres for regulating and controlling a local inflammation microenvironment and promoting nerve regeneration. The method comprises the following steps: preparing liposome loaded with ginsenoside Rg1; preparing a GM microsphere loaded with a stromal cell-derived factor 1 alpha (SDF1 alpha); and preparing the inflammation regulation nerve regeneration promoting composite microspheres. The composite microsphere can reduce inflammatory response, reduce scar tissue formation, promote angiogenesis, continuously release SDF1 alpha and promote endogenous stem cell recruitment and neural differentiation. Therefore, the composite microsphere is a functional biological scaffold for firstly regulating and controlling local microenvironment inflammation of spinal cord injury and then promoting collection and differentiation of endogenous stem cells for innovative sequential inflammation regulation and nerve regeneration, and a new strategy is provided for treating spinal cord injury by tissue engineering.

The present application relates to a kind of multifunctional saponins molecularly imprinted polymer template molecule, molecularly imprinted polymer and its application, belong to plant component refining technical field.The molecularly imprinted polymer of the present application uses virtual template molecule, the template molecule contains hydrogen bond donor and strong electronic effect, it has good adsorption performance to natural saponins compound molecules such as Jiumu saponin AIII, Jiumu saponin BII, Jiumu saponin BIII, Sanqi saponin R1, ginsenoside Rg1, ginsenoside Rg3, ginsenoside Rh2, Tribulus saponin K, Tribulus saponin D, Platanus orientalis saponin D, Shandeng saponin B, Chonglou saponin I, Chonglou saponin II, Chonglou saponin VI.The virtual template molecule is low in cost, can be used for the large-scale preparation of molecularly imprinted polymer, significantly reduces the extraction cost of natural saponins compound.

The application discloses a SNP site and KASP marker combination related to contents and proportions of ginsenosides Rg1 and Rb1 in Panax notoginseng and application thereof, and belongs to the technical field of medicinal plant molecular breeding and quality evaluation. In view of the problems of lack of molecular markers synchronously related to contents and proportions of ginsenosides Rg1 and Rb1 in Panax notoginseng and long breeding cycle in the prior art, nine SNP site combinations located on a Chr11 chromosome of Panax notoginseng genome are screened, and a KASP marker combination and primer combination are developed based on four sites of SNP3-SNP6 among them. The KASP marker combination has strong specificity, is convenient to detect, has high throughput, is low in cost, and can accurately identify the contents and proportions of Rg1 and Rb1 in Panax notoginseng samples. The application can be used for Panax notoginseng germplasm resource screening and molecular marker assisted breeding, early identification of target traits is realized, the breeding cycle is shortened, the breeding efficiency is improved, and technical support is provided for directional cultivation of Panax notoginseng high-quality varieties.

The invention provides a drug combination composition for treating or / and improving attention impairment and application thereof, and relates to the technical field of biological medicine, the drug combination composition comprises isorhynchophylline and ginsenoside Rg1, and the isorhynchophylline and ginsenoside Rg1 are creatively combined to be used as a drug for treating or / and improving attention impairment. Researches show that the combination of isorhynchophylline and ginsenoside Rg1 has a more significant effect of treating or / and improving attention impairment than single isorhynchophylline or ginsenoside Rg1, provides a new strategy and idea for treating or / and improving attention impairment, and has very significant significance.

The invention provides a universal technical method for detecting non-toxic Chinese herbal medicine based on UPLC-QTOF-MS, and relates to the field of traditional Chinese medicine detection and analysis. The method comprises the following steps: S1, crushing non-toxic traditional Chinese medicinal materials; s2, preparing a to-be-detected sample solution; s3, preparing a QC accompanying standard product; s4, carrying out liquid mass analysis on the to-be-detected sample; and S5, processing mass spectrum information data. The method is characterized in that the QC standard substance in the step S3 is one or more of araflavin, aurantio-obtusin, patchouli ketone, apigenin, mangiferin, ginsenoside Rg1 and timosaponin, and chromatography-mass spectrometry conditions are defined in the step S4. The method disclosed by the invention has the advantages that a universal technical method is established instead of aiming at each specific traditional Chinese medicine, and targeted identification and analysis are not solved, so that a unified system is formed by inspection and analysis of different non-toxic Chinese herbal medicines, and non-targeted identification and analysis can be realized according to result differences on the premise of controlling the method differences.

The application discloses an application of a kit for detecting a SNP molecular marker related to the content of ginsenoside Rg1 in panax notoginseng in breeding of the content of ginsenoside Rg1 in panax notoginseng, wherein the SNP molecular marker is SNP4-117624472, is located at the 117624472th base of a Chr11 chromosome, and the mutation type is C / A. The KASP primer combination developed in the application can accurately distinguish panax notoginseng with high and low contents of ginsenoside Rg1, and can be applied to molecular assisted marker breeding of panax notoginseng, shortens the breeding cycle of new varieties, and has low detection cost, is not limited by environment, has high accuracy of detection results, and is easy to repeat. The application has important theoretical and practical guiding significance for accelerating the genetic improvement process of panax notoginseng with high content of ginsenoside Rg1 and improving the breeding selection efficiency.

The invention relates to the technical field of medicines for treating intestinal ischemia-reperfusion injury, and discloses a medicine for treating intestinal ischemia-reperfusion injury and a preparation method thereof. Comprising 10 to 25 parts of rosmarinic acid, 5 to 15 parts of betaine, 3 to 10 parts of glutamine, 10 to 25 parts of salvianolic acid B, 5 to 15 parts of astragaloside, 3 to 10 parts of ginsenoside Rg1, 2 to 8 parts of curcumin, 5 to 12 parts of ophiopogon japonicus polysaccharide, 2 to 6 parts of notoginsenoside R1, 3 to 7 parts of total flavonoids of oldenlandia diffusa and 4 to 9 parts of angelica sinensis polysaccharide. The medicine disclosed by the invention can be used for relieving intestinal edema, repairing oxidative injury, clearing excessive ROS, improving SOD activity, blocking oxidative stress injury, inhibiting epithelial cell apoptosis, reducing intestinal permeability and maintaining mucous membrane integrity, and has an excellent treatment effect on intestinal ischemia reperfusion injury.

The application discloses a quality detection method for a compound phyllium panax schisandra preparation, and belongs to the technical field of drug detection and analysis. The traditional Chinese medicine is composed of phyllium, panax and schisandra. Qualitative analysis is conducted on the phyllium, panax and schisandra in the compound by using a thin layer chromatography method; and the contents of gallic acid, ginsenoside Rg1 and schisandrin A in the compound are determined by using a high performance liquid chromatography method. The thin layer chromatography method is one of classical traditional Chinese medicine analysis methods, and has the advantages of rapidness, convenience and the like; the high performance liquid chromatography method is also one of classical traditional Chinese medicine analysis methods, and has the advantages of mature technology, good stability, high universality and the like, can be used for widely and accurately detecting chemical components in a complex traditional Chinese medicine compound, the content determination method passes the method validation, has good linear relationship, and the precision, stability, repeatability and recovery rate meet the regulations, and the combination of qualitative analysis and quantitative analysis lays a foundation for establishing the quality standard of the compound preparation.

The present disclosure provides a medicament for treating brain diseases. Specifically, provided is a pharmaceutical composition. The active ingredient of the pharmaceutical composition comprises: (a) a first active ingredient, wherein the first active ingredient is a pharmaceutically acceptable salt of salvianolic acid; and (b) a second active ingredient, wherein the second active ingredient is ginsenoside or a pharmaceutically acceptable salt thereof. The pharmaceutically acceptable salt of salvianolic acid is selected from the following group: magnesium salvianolate B, calcium salvianolate B, magnesium salvianolate A, sodium rosmarinate, and a combination thereof. The ginsenoside is selected from the following group: ginsenoside Rg1, ginsenoside Rh2, ginsenoside Rb1, and a combination thereof. The mass ratio of the first active ingredient to the second active ingredient is 1:(0.1-10), wherein the mass ratio is based on the pharmaceutically acceptable salt of salvianolic acid and ginsenoside. Also provided is use of the pharmaceutical composition in preventing or treating brain diseases.

The invention relates to the field of medicines, in particular to a composition, a preparation method of a pseudo-ginseng extract and application of the pseudo-ginseng extract. The composition is prepared from notoginsenoside R1, ginsenoside Rg1 and ginsenoside Re, and the weight ratio of the notoginsenoside R1 to the ginsenoside Rg1 to the ginsenoside Re is (2.05 to 2.5) to (7.5 to 9.4) to 1. The invention also provides application of the composition in preparation of drugs for preventing and / or treating cardiovascular and cerebrovascular diseases. The preparation method of the pseudo-ginseng extract provided by the invention comprises the following steps: cleaning pseudo-ginseng, removing impurities, pretreating, crushing, mixing with ethanol, soaking, percolating, collecting percolate, concentrating, and filtering to obtain the pseudo-ginseng extract. The composition provided by the invention can be used for effectively treating cardiovascular and cerebrovascular diseases, and can generate a better treatment effect compared with the existing composition adopting panaxatriol saponin.

This invention discloses a kit for detecting SNP molecular markers related to the content of ginsenoside Rg1 in Panax notoginseng, and its application in breeding for the ginsenoside Rg1 content trait in Panax notoginseng. The SNP molecular marker is SNP8-117644135, located at base 117644135 on chromosome Chr11, with a mutation type of C / T. The KASP primer combination developed in this invention can accurately distinguish between Panax notoginseng with high and low ginsenoside Rg1 content, and can be applied to molecular marker-assisted breeding of Panax notoginseng, shortening the breeding cycle of new varieties. Furthermore, the detection cost is low, it is not limited by the environment, and the detection results are highly accurate and easily reproducible. This has important theoretical and practical guiding significance for accelerating the genetic improvement process of breeding Panax notoginseng with high ginsenoside Rg1 content and improving breeding selection efficiency.

The invention discloses a quality detection method of a compound phyllanthus emblica, ginseng and schisandra chinensis preparation, and belongs to a medicine detection and analysis technology. The traditional Chinese medicine is composed of emblic leafflower fruit, ginseng and Chinese magnoliavine fruit. Carrying out qualitative analysis on the emblic leafflower fruit, the ginseng and the Chinese magnoliavine fruit in the compound by using a thin layer chromatography; and determining the contents of gallic acid, ginsenoside Rg1 and schizandrin in the compound by using a high performance liquid chromatography. The thin-layer chromatography is one of classical traditional Chinese medicinal material analysis methods, and has the advantages of rapidness, convenience and the like; the high performance liquid chromatography is also one of classical traditional Chinese medicinal material analysis methods, has the advantages of mature technology, good stability, high universality and the like, can be used for widely and accurately detecting the chemical components in the complex traditional Chinese medicinal compound, passes methodology verification, and is good in linear relation and high in accuracy. The precision, the stability, the repeatability, the recovery rate and the like all meet regulations, and the combination of qualitative analysis and quantitative analysis lays a foundation for the establishment of the quality standard of the compound preparation.

The invention discloses a micropterus salmoides rhabdovirus attenuated freeze-dried vaccine activator. The micropterus salmoides rhabdovirus attenuated freeze-dried vaccine activator comprises ginsenoside Rg1. The invention further discloses application of the ginsenoside Rg1 in preparation of the micropterus salmoides rhabdovirus attenuated freeze-dried vaccine and a method for activating the micropterus salmoides rhabdovirus attenuated freeze-dried vaccine. After the ginsenoside Rg1 is used for activating the vaccine, the virus titer is high, the high activity of the freeze-dried vaccine can be maintained, the immune protection effect of the largemouth bass rhabdovirus attenuated freeze-dried vaccine can be remarkably improved through soaking immunization, and a foundation is laid for application of the largemouth bass rhabdovirus attenuated vaccine.

Provided is a pharmaceutical composition and application thereof, specifically, said pharmaceutical composition comprises: salvianolic acid B as a first active ingredient; and ginsenoside Rg1 as a second active ingredient, and the weight ratio of the first active ingredient to the second active ingredient being 5:(1-4.5). The pharmaceutical composition has a better active-ingredient proportion than the prior art, has a better therapeutic efficacy in preventing and / or treating ischemic diseases, and ischemia-reperfusion tissue or organ damage, and can be used for treating ischemia and / or ischemia-reperfusion damage of different tissues and organs.

The invention discloses a medical dressing and a preparation method thereof. The dressing is prepared from the following components in parts by weight: 30 to 100 parts of sodium carboxymethyl cellulose, 30 to 50 parts of polyethylene glycol, 30 to 50 parts of sodium alginate, 20 to 30 parts of sodium hyaluronate, 5 to 15 parts of a humectant, 3 to 8 parts of a plant extract, 2 to 6 parts of compound polysaccharide, 0.01 to 0.5 part of a growth factor, 0.2 to 0.6 part of balanophora balanophora, 0.1 to 0.5 part of ginsenoside Rg1 and 300 to 600 parts of deionized water. The medical dressing disclosed by the invention is good in antibacterial and anti-inflammatory effects and has a certain repairing effect on scars. The termitomyces albuminosus extract and the callicarpa bodinieri extract in the components are combined for use, so that the antibacterial effect is enhanced; the rosa roxburghii tratt polysaccharides and the aloe polysaccharides are combined to resist inflammation and promote wound healing; balanineine and ginsenoside Rg1 are combined for use to inhibit scar generation.

The invention discloses application of ginsenoside Rg1 in preparation of a product for treating oxaliplatin-induced liver injury, and belongs to the technical field of medicines. Experimental verification shows that after ginsenoside Rg1 is administrated, the survival rate of HL-7702 human hepatocytes induced by oxaliplatin is increased, the content of transaminase indexes AST and ALT in the cells is obviously reduced, the content of active oxygen is obviously reduced, and the condition of mouse liver injury can be obviously improved. The experimental results show that the ginsenoside Rg1 can improve the liver injury induced by oxaliplatin, and a new technical thought is provided for preparing the product for treating the liver injury induced by oxaliplatin.

The application discloses Jianyang capsule fingerprint spectrum and a construction method and application thereof, and relates to the technical field of quality detection. The construction method of the Jianyang capsule fingerprint spectrum comprises the following steps: preparing a control solution by using ginsenoside Rg1, ginsenoside Rb1, notoginsenoside R1, ganoderic acid A, primulaverin and 2,3,5,4'-tetrahydroxystilbene-2-O-beta-D-glucoside; preparing a test solution by using powders of Jianyang capsules of different batches; and performing high performance liquid chromatography analysis on the control solution and the test solution respectively to generate the Jianyang capsule fingerprint spectrum. The main peak and each chromatographic peak of the Jianyang capsule fingerprint spectrum obtained by the application are well separated, the Jianyang capsule fingerprint spectrum is applied to quality control detection of Jianyang capsules, the quality of the products can be comprehensively monitored, the consistency, controllability and stability of the product quality are ensured, and therefore, the quality of the Jianyang capsule products can be more comprehensively monitored.

The invention discloses a method for detecting notoginsenoside R1, ginsenoside Rg1 and ginsenoside Rb1 in a heart-stabilizing composition.The method comprises the steps of preparation of a reference solution, preparation of a test solution and determination through a high performance liquid chromatography. The notoginsenoside R1, the ginsenoside Rg1 and the ginsenoside Rb1 can be detected at the same time, the separation effect of the notoginsenoside Rb1 is good, and a new alternative method is provided.

The application discloses a kind of β-glucosidase GE000505 for saponin conversion and its preparation method and application, belong to biotechnology field, the amino acid sequence of the β-glucosidase GE000505 as shown in SEQ ID NO.1, it is encoded by the gene with nucleotide sequence as shown in SEQ ID NO.2.This β-glucosidase GE000505 of the application can convert high content ginseng and sanchi saponin into rare saponin R2, Rg3, Rg2 and Rh1, can convert sanchi saponin R1 into R2 entirely, convert ginsenoside Rd into Rg3 entirely, convert ginsenoside Re into Rg2 entirely, convert ginsenoside Rg1 into Rh1 entirely, convert ginsenoside F1 into aPPT entirely, convert ginsenoside F2 into aPPD entirely, solve the problem that existing β-glucosidase is not resistant to alcohol in the conversion of ginsenoside.

The application provides a composition for improving intestinal digestive enzyme activity and application thereof, and belongs to the technical field of animal medicine. The composition is composed of double-kidney polysaccharide, ginsenoside Rb1 and ginsenoside Rg1. In the composition, the mass ratio of the double-kidney polysaccharide, the ginsenoside Rb1 and the ginsenoside Rg1 is 90:5:5 or 95:2.5:2.5, preferably 90:5:5, and the intestinal digestive enzyme is specifically duodenal trypsin and amylase. Experimental results show that the composition can significantly synergistically improve the activities of the duodenal trypsin and amylase of laying hens, improve the feed utilization rate, thereby improve the egg production rate, improve the egg weight and the eggshell strength, and effectively improve the breeding benefit of the laying hens.

The invention belongs to the technical field of traditional Chinese medicine extraction, and particularly relates to an extraction method of a high-activity ginseng extract, which is used for improving the conversion and extraction efficiency of rare ginsenoside Rg1, Rg3, Rg5, Rh2 and Compound K. The extraction method combines microbial fermentation, electrostatic field wall breaking and supercritical CO2 extraction, the high-voltage pulse electric field induces ginseng cells to generate an electroporation effect, permeability of cell membranes and cell walls is improved, supercritical CO2 extraction has high cell permeability, the extraction rate and purity of ginsenoside are improved, and in addition, a catalytic promoter added in the extraction process is beneficial to conversion catalysis of rare ginsenoside components.

The invention belongs to the technical field of traditional Chinese medicines, and provides a pharmaceutical composition containing an effective component of American ginseng, a pharmaceutical preparation and application of the pharmaceutical composition and the pharmaceutical preparation in treating chronic obstructive pulmonary diseases. The pharmaceutical composition is prepared from the following components in parts by weight: 1 to 2 parts of ginsenoside Rg1, 1 to 2 parts of ginsenoside Rc, 0.5 to 1 part of oleanolic acid, 0.1 to 0.5 part of notoginsenoside R1 and 0.05 to 0.1 part of notoginsenoside Fe. Specific American ginseng saponin components are compounded, and the dosage of each component is optimized, so that the composition has remarkable effects of protecting the lung function of a COPD mouse caused by cigarette smoke exposure, inhibiting expression of inflammatory factors and relieving in-vivo oxidative stress injury, the repairing effect is remarkable, and in order to improve the effect of American ginseng in treatment of COPD, the composition has a good application prospect. And an important basis is provided for fully exerting the effects of all active components in the American ginseng.