Applications of Baweixihonghua bleeding stopping powder in preparation of leukopenia treatment drugs
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A technology of leukopenia and saffron, which is applied in the field of medicine, can solve the problems of no research or report on leukopenia of Bawei saffron Zhixue powder, and achieve the effect of restoring the number of nucleated cells in bone marrow and improving leukopenia
Inactive Publication Date: 2016-11-23
SHANDONG JINHE DRUG RES DEV
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[0004] After patent and literature search, no research or report on the use of Bawei Xihonghua Zhixue Powder or other preparations of its formulation in the treatment of leukopenia was found
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Embodiment 1
[0019] Example 1. The effect of Bawei Xihonghua Zhixue Powder on animal leukopenia caused by radiotherapy and chemotherapy
[0020] 1. Experimental materials
[0021] Experimental animals: male Kunming mice, body weight (20±2) g, license number: SCXK (Lu) 2008-0002, provided by Shandong Lukang Pharmaceutical Co., Ltd.
[0022] Sample: Bawei Xihonghua Zhixue San (Jin He Tibetan Medicine Co., Ltd., batch number 20130508).
[0023] Reagents: Western medicine Squalene (100mg / kg), Shanghai Xinyi Wanxiang Pharmaceutical Co., Ltd., batch number 20130723; Cyclophosphamide, produced by Jiangsu Hengrui Pharmaceutical Co., Ltd., batch number: 13110621; Cytarabine, Shanghai Hua Produced by United Pharmaceutical Factory, batch number 0512048; EDTA-K2, produced by Sinopharm Chemical Reagent Co., Ltd., batch number: F20130423.
[0024] Instruments: XT-18001 automatic biochemical detector (Japan East Asia Company), CELL-DYN-1500 automatic blood cell counter (American Abbott Company).
[0025] 2. Experi...
Embodiment 2
[0073] Example 2. Application of Bawei Xihonghua Zhixue San in the preparation of drugs for treating leukopenia
[0074] Bawei Xihonghua Zhixue San is used in combination with scyllohydrin at the same time.
Embodiment 3
[0075] Example 3 Application of Bawei Xihonghua Zhixue San in the preparation of drugs for treating leukopenia
[0076] Bawei Xihonghua Zhixue San is used in combination with Li Kejun tablets.
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Abstract
The invention discloses applications of Baweixihonghua bleeding stopping powder in preparation of leukopenia treatment drugs, and belongs to the field of medicine. According to the present invention, the technical bias of the Baweixihonghua bleeding stopping powder in the application field is overcome; and the animal research results show that the leukopenia caused by conventional radiotherapy and chemotherapy can be significantly improved (P<0.05) with the Baweixihonghua bleeding stopping powder, the number of the bone marrow nucleated cell can be restored, the effect of the Baweixihonghua bleeding stopping powder is equivalent to the effect of the traditional leucocyte increasing drug batyl alcohol, and the Baweixihonghua bleeding stopping powder can be used to prepare the leukopenia treatment drug.
Description
Technical field [0001] The invention relates to the application of Bawei Xihonghua Zhixue San in the preparation of drugs for treating leukopenia, and belongs to the field of medicine. Background technique [0002] Malignant tumors are one of the most important factors affecting human life and health, and chemical / radiotherapy is one of the most important methods of current tumor treatment. Chemo / radiotherapy has more toxic side effects. While killing tumor cells, it also has great damage to normal human cells, such as leukopenia. In the early stage of leukocyte decline after radiotherapy and chemotherapy, the application of white blood boosting drugs can significantly increase the number of white blood cells, so that patients can complete chemotherapy effectively and smoothly, and improve their survival rate and quality of life. [0003] Bawei Xihonghua Zhixue San standard number: WS3-BC-0244-95, included in the standard issued by the Ministry of Tibetan Medicine, the main ingred...
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