35results about How to "Recovery quantity" patented technology

The machine comprises: a brewing unit (3); a water reservoir (7); a boiler (11) for the production of hot water to supply to the brewing unit; a coffee container (13); an electronic control unit (27); a user interface (33). At least one capacitive sensor (31) is associated to the coffee container to detect the quantity of residual coffee in the container (13). The sensor is connected to the electronic control unit, which is programmed to supply to a user by means of the interface at least a piece of information regarding the quantity of coffee in said container.

The invention discloses a method for recovering a heavily polluted water body in a city by utilizing aeration-to-sediments. The method comprises the following steps: (1) aeration to sediments: aerating the sediments in the water body by an aerating apparatus to enable the sediments to suspend and utilizing the suspended sediments to adsorb pollutants such as organics, ammonia, nitrogen and phosphorus in the water body, thereby achieving the purpose of oxidation and removal through the aeration method; (2) sedimentation: naturally sedimenting the suspended sediments. According to the method, resource is saved; no chemical or biological risk is brought to the water body; the sediments in the water body are purified via aeration and oxidation manners to reduce the sediment dredging frequency while pollutants in the water body are removed.

The invention discloses a releasing method for porphyra haitanensis seedlings. The method includes drying lobate bodies of the porphyra haitanensis in the shade, preparing into carpospores liquid, performing inoculation into shells, growing naturally into shell filaments, and performing cultivation to a mature-stage shell filaments; and placing the mature-stage shell filaments in stone marsh in an intertidal zone with a water depth of 10-20cm after the ebb tide and in reefs in the intertidal zone one hour before the flood tide for natural release, performing broadcast sowing on the mature-stage shell filaments in a neritic region for the natural release, and suspending the mature-stage shell filaments in a mesh bag on the lower portion of a positioned float in an abyssal region for the natural release, wherein the neritic region refers to an ocean area with a water depth of 6-10m after the ebb tide, the abyssal region refers to an ocean area with a water depth larger than10m after the ebb tide, the lower portion of the positioned float is submerged for 0.5-1.5m under the water level, and the natural release continues for 2-3 years. According to the method, the germplasm of the porphyra haitanensis can be improved, natural resources of the porphyra haitanensis can be recovered, and ecological environment of the seaweed can be restored.

The invention discloses an eye drop for treating eye dryness. The pH value of the eye drop is 5.0-7.0, the eye drop comprises effective components of 5-hydroxy-1-beta-D-furanose-1H-imidazole-5-carboxamide, and specifically the eye drop consists of the following components in percentage by weight: 0.05-0.1% of 5-hydroxy-1-beta-D-furanose-1H-imidazole-5-carboxamide, a proper amount of a pH value adjusting agent, 0.01-3% of an iso-osmotic agent, 0.003-0.5% of a bacteriostatic agent, 0.001-0.5% of a stabilizer, 0.01-0.5% of a tackifier, 2-5% of a solubilizer and the balance of water. Through partial treatment of the eye drop, epithelial barrier functions of dry eye mouse cornea can be protected, the number of goblet cells of cornea can be recovered, and relatively good anti-inflammatory and immunity inhibition effects can be achieved.

The invention relates to an immune nutrition composition and application thereof. The immune nutrition composition disclosed by the invention comprises the following components in parts by weight: 45-50 parts of hydrolyzed small molecular protein, 10-15 parts of water-soluble dietary fiber, 20-25 parts of edible mushrooms extract, 2-5 parts of selenium-enriched yeast, 5-10 parts of fructo oligosaccharides and 0.63-1.8 parts of vitamin. The immune nutrition composition disclosed by the invention can be used in cancer therapy. According to the immune nutrition composition disclosed by the invention, the cancer chemotherapy and radiotherapy tolerance can be improved, and the capability of killing tumor cells by CIK cells can be improved.

The invention relates to an immune nutrition composition and application thereof. The immune nutrition composition disclosed by the invention comprises the following components in parts by weight: 45-50 parts of hydrolyzed small molecular protein, 10-15 parts of water-soluble dietary fiber, 20-25 parts of edible mushrooms extract, 2-5 parts of selenium-enriched yeast, 5-10 parts of fructo oligosaccharides and 0.63-1.8 parts of vitamin. The immune nutrition composition disclosed by the invention can be used in cancer therapy. According to the immune nutrition composition disclosed by the invention, the cancer chemotherapy and radiotherapy tolerance can be improved, and the capability of killing tumor cells by CIK cells can be improved.

The invention belongs to the field of health care products, and particularly relates to a green-plum-contained health care food composition capable of regulating intestinal flora, and a preparation method. The green-plum-contained health care food composition capable of regulating intestinal flora is prepared from the following preparation raw materials: green plum, the root of kudzu vine, honey, Chinese angelica, Chinese yam, galangal, rhizoma alpiniae officinarum, hawthorn furit, radix platycodi and alpiniae oxyphyllae fructus. The green-plum-contained health care food composition capable of regulating intestinal flora has the advantages of scientific and reasonable compatibility, outstanding effect, safety, reliability and convenience in eating, can effectively regulate the composition and the growth of the intestinal flora and has the health care efficacies of high probiotics, the improvement of immunity and the improvement of stomach functions.

The invention discloses a fully mixed pellet feed for quickly fattening beef cattle and sheep. The concentrated feed comprises 5-30 parts of corn, 5-15 parts of wheat and by-products thereof, 2-8 parts of corn germ meal, 5-20 parts of corn by-products, 5-15 parts of corn DDGS, 1-5 parts of soybean meal, 1-5 parts of other cake meal, 1-5 parts of stone powder, 0.3-3 parts of calcium hydrogen phosphate, 0.1-2 parts of sodium chloride, 1-5 parts of cane molasses, 1-15 parts of a mycopeptidase culture, 0.01-0.05 part of a vitamin premix for beef cattle and sheep, 0.01-0.1 part of an antioxidant, 0.1-1 part of magnesium oxide, 0.1-0.4 part of beef cattle and sheep trace element premix and 0.5-2 parts of baking soda. The invention belongs to the technical field of feed, and particularly relates to the fully mixed pellet feed for quickly fattening beef cattle and sheep, which ensures the feed quality, increases the feed intake, increases the daily gain and can be quickly slaughtered.

The invention discloses an application of dendrobium polysaccharide in the preparation of reproductive injury recovery drugs after cancer chemotherapy. The dendrobium polysaccharide has obvious therapeutic effect and small side effects, which can effectively reduce the damage caused by platinum anticancer drugs to the reproductive system, not only the sperm quantity of mice is significantly increased, the sperm quality is also improved, the antioxidant activity of mouse testicular tissue is also effectively improved, and in mouse testicular tissue, the level of SOD, GPx, GSH and CAT is obviously increased while the level of MDA is obviously decreased. The dendrobium polysaccharide with wide source is simple in extraction and purification method, and the obtained dendrobium polysaccharide is high in sugar content and suitable for large-scale production; the dendrobium polysaccharide has a good prospect in the preparation and clinical application of reproductive injury recovery drugs after cancer chemotherapy.

The invention discloses pleurotus citrinopileatus polysaccharide and application thereof, and relates to the field of development and utilization of natural products. The pleurotus citrinopileatus polysaccharide comprises xylose, glucose, galactose, glucuronic acid, fucose, fructose and arabinose. The invention further discloses application of the pleurotus citrinopileatus polysaccharide in preparation of drugs for treating sarcopenia caused by cancers. A colorectal cancer cachexia mouse muscle attenuation experiment proves that the pleurotus citrinopileatus polysaccharide can increase the body weight and spleen weight of a sarcopenia mouse, recover the form, quantity and density of muscle fibers, reduce inflammatory response and expression of sarcopenia symbolic proteins Atrogin-1 and MuRF-1, and relieve the sarcopenia symptom caused by tumors. According to the pleurotus citrinopileatus polysaccharide and the application thereof, the new effect of the pleurotus citrinopileatus polysaccharide is found, and a new thought is provided for development and utilization of pleurotus citrinopileatus and treatment of the sarcopenia caused by the cancer.

The invention is applicable to the field of firefly cultivation, and provides a method for restoring habitats and cultivating fireflies and rice. According to the invention, firstly a plot layout is designed, and then a system for restoring habitats and cultivating fireflies and rice is reasonably designed, so that the local ecological environment can be comprehensively and systematically restored, a large amount of farmland water can be saved, and the purposes of recycling the farmland water and realizing zero emission of pollution are achieved. Meanwhile, the fireflies and the rice are co-cultivated, so that the ecological environment restoration degree is inspected, and the fireflies become visual inspection standards of organic healthy rice foods. According to the method, extremely high ecological benefits can be generated through ecological restoration, great social benefits can be brought by restoring the ecological environment, and huge economic benefits can be generated by selling healthy ecological agricultural products and ecological tourism.

The invention discloses an animal testis extract and a preparation method and application thereof. The invention provides a preparation method of an animal testis extract, which is characterized by comprising the following steps: (1) inspecting the appearance of an animal testis, and removing a non-substantial part; (2) crushing and homogenizing the animal testis; (3) freezing and unfreezing the homogenized animal testis to obtain animal testis freeze-thawed liquid; and (4) freeze-drying the animal testis freeze-thawed liquid. Compared with artificially synthesized testosterone, the animal testis extract provided by the invention has better biological safety. The animal testis extract provided by the invention also has the functions and effects of promoting sexual desire of human or male animals, promoting growth and development of human or male animals and gonad growth and development, and increasing and recovering the sperm quantity of human or male animals.

The invention discloses application of a hepcidin antagonist LDN193189 and derivatives thereof to drug preparation, belongs to the technical field of medicine and provides new application of the hepcidin antagonist LDN193189 and the derivatives thereof to preparation of drugs for treating bone marrow form acute radiation sickness and radiation-induced hemocytopenia. The LDN193189 and derivatives thereof are adopted for intraperitoneal injection of mice irradiated by the lethal dose so that the survival rate of the irradiated mice can be increased to 40% (120 days), and the numbers of peripheral blood leukocytes and lymphocytes are obviously increased; the number of bone marrow granulocyte and megakaryocytic hematopoietic progenitor cells is obviously recovered; the survival rate of spleniclymphocytes is obviously recovered; and the number of the splenic lymphocytes is obviously increased (HE splices), and the LDN193189 and the derivatives thereof have good effects on treatment of bonemarrow form acute radiation sickness and radiation-induced hemocytopenia.

The invention discloses dandruff removing cosmetic containing propionibacterium. The dandruff removing cosmetic is prepared from, by weight, 0.1-0.5 part of propionibacterium suspension, 8-30 parts of surfactant, 0.2-8 parts of thickener, 0.1-5 parts of conditioner, 0.1-3 parts of humectants and 40-60 parts of sterile water. The concentration of the propionibacterium suspension is (0.2-4)*10<2> cfu / ml, the temperature of the dandruff removing cosmetic is 2-8 DEG C, and the pH value of the dandruff removing cosmetic is 5.5-7.3. The invention further discloses a preparing method and a using method of the dandruff removing cosmetic containing propionibacterium. Compared with the prior art, the dandruff removing cosmetic has the advantages that propionibacterium is directly added into the dandruff removing cosmetic, the normal number of propionibacterium in the scalp can be recovered after using the dandruff removing cosmetic, dandruff is removed fast and remarkably and does not relapse, and the dandruff removing cosmetic has broad application prospects.

This invention discloses a method for preparing HVC NPs for the diagnosis and treatment of Parkinson's disease and their applications. The probe HV in the HVC NPs responds to H2O2 and viscosity, utilizing near-infrared fluorescence imaging capabilities to achieve real-time monitoring of Parkinson's disease biomarkers, helping us better understand the occurrence and development of Parkinson's disease. With the assistance of RVG29, the HVC NPs effectively cross the blood-brain barrier. The curcumin within them can reduce cell apoptosis, lower oxidative stress levels, scavenge excess reactive oxygen species, combat inflammation, and reduce α-synuclein aggregation, demonstrating effective anti-Parkinson's disease effects at the cellular and experimental animal levels. This nanomaterial provides a new strategy for integrated research on the diagnosis and treatment of Parkinson's disease.

The invention provides a traditional Chinese medicine composition for treating leucopenia as well as a preparation method and application thereof, and belongs to the technical field of traditional Chinese medicines. The traditional Chinese medicine composition for treating leucopenia is prepared from the following raw materials in parts by weight: 10-20 parts of ginseng, 10-30 parts of lucid ganoderma, 15-30 parts of astragalus membranaceus, 10-20 parts of rhizoma polygonati and 10-30 parts of venison. According to the traditional Chinese medicine composition, all the medicinal materials can achieve a synergistic effect, the bone marrow hematopoiesis function is promoted, generation and release of leucocytes are accelerated, leucopenia caused by bone marrow suppression can be remarkably improved, the immunity of the organism is improved, the life quality of a patient is improved, and the traditional Chinese medicine composition is high in safety, small in side effect and suitable for being taken for a long time.

The invention discloses a preparation method and application of nanoparticles HVC NPs for diagnosis and treatment of Parkinson's disease. The probe HV in the HVC NPs can respond to H2O2 and viscosity, the near-infrared fluorescence imaging capability is played, real-time monitoring of the Parkinson's disease biomarker is achieved, and people are helped to better explore occurrence and development of Parkinson's disease. HVC NPs effectively permeates the blood brain barrier under the assistance of RVG29, curcumin in HVC NPs can relieve apoptosis, reduce the oxidative stress level, eliminate excessive active oxygen, resist inflammation, reduce alpha-syn aggregation and the like, and the effect of effectively resisting Parkinson's disease is shown at the cell and experimental animal level. The nano material provides a new strategy for integrated research on diagnosis and treatment of Parkinson's disease.

The invention discloses an eye drop for treating dry eye, the pH is 5.0-7.0, and its active ingredient is 5-hydroxyl-1-beta-D-furanosyl-1H-imidazole-5-carboxamide, specifically It has the following composition by weight and volume percentage: 5-hydroxyl-1-beta-D-furanosyl-1H-imidazole-5-carboxamide 0.05-0.1%, an appropriate amount of pH regulator, and isotonic agent 0.01-3% , bacteriostat 0.003-0.5%, stabilizer 0.001-0.5%, thickener 0.01-0.5%, solubilizer 2-5%, and the balance is water. The local treatment of the eye drops of the invention can protect the corneal epithelial barrier function of dry eye mice, restore the number of conjunctival goblet cells, and have good anti-inflammatory and immunosuppressive effects.

The invention discloses an application of a brassica napus BnaSPT3 gene in promoting growth of pods of dicotyledons. A base sequence of the brassica napus BnaSPT3 gene is shown as SEQ ID NO.1. The application comprises the following steps: (1) linking the brassica napus BnaSPT3 gene into a plant expression vector, so that a recombinant expression vector is constructed; and (2) transforming the recombinant expression vector into a recipient plant. The invention also discloses the recombinant expression vector containing the brassica napus BnaSPT3 gene and a transformant containing the recombinant expression vector. According to the application provided by the invention, by cloning the brassica napus BnaSPT3 gene, implementing genetic transformation in arabidopsis thaliana and through excessive expression of the exogenous brassica napus BnaSPT3 gene, the size of arabidopsis thaliana spt mutant pods can be obviously increased, and the number of seeds can be recovered. On the basis of genetic engineering technology, over-expression of the brassica napus BnaSPT3 gene in a receptor is achieved, and the size of the pods is changed; therefore, the invention is conducive to high-yield researches.

The invention relates to a capsule for treating lymphatic system diseases. The capsule is a Chinese patent medicine for effectively treating lymphatic diseases. A method comprises the following steps: extracting effective constituents of angelica sinensis, astragalus membranaceus, ligusticum wallichii, euphorbia kansui, euphorbia pekinensis, coptis chinensis, red date and poria cocos, albumen powder, whole worm powder, centipede powder and mineral resource fulvic acid, mixing and then filling into the capsule. The lymphatic disease patient can recover physical ability as long as taking the capsule on time.

The invention discloses an oligomeric guluronic acid phosphate as well as a preparation method and an application thereof. The molecular framework of oligomeric guluronic acid phosphate is a linear polymer of L-guluronic acid connected through alpha-(1,4)-glucosidic bonds, in the formula, R1 is pharmaceutical salt such as H, Li, Na, K, Ca or Mg, R2 is H or PO3<2->, the salting mode of -PO32- is accordant with that when R1 is taken as a substituent group, and n is less than or equal to 20. By adopting the oligomeric guluronic acid phosphate, the situation of low immunity of mice caused by cyclophosphamide can be alleviated, the major performance includes that the immune viscera / weight ratio can be increased, the humoral immunity and the cell immunity can be improved, the phagocytic ability of monocyte macrophages is improved, and the numbers of leukocytes and lymphocytes in peripheral hemogram can be remarkably increased. The pharmacology experiment result shows that the oligomeric guluronic acid phosphate disclosed by the invention can be used for preparing medicines, food or functional products with immunological enhancement.

The invention discloses an oligomeric guluronic acid phosphate as well as a preparation method and an application thereof. The molecular framework of oligomeric guluronic acid phosphate is a linear polymer of L-guluronic acid connected through alpha-(1,4)-glucosidic bonds, in the formula, R1 is pharmaceutical salt such as H, Li, Na, K, Ca or Mg, R2 is H or PO3<2->, the salting mode of -PO32- is accordant with that when R1 is taken as a substituent group, and n is less than or equal to 20. By adopting the oligomeric guluronic acid phosphate, the situation of low immunity of mice caused by cyclophosphamide can be alleviated, the major performance includes that the immune viscera / weight ratio can be increased, the humoral immunity and the cell immunity can be improved, the phagocytic ability of monocyte macrophages is improved, and the numbers of leukocytes and lymphocytes in peripheral hemogram can be remarkably increased. The pharmacology experiment result shows that the oligomeric guluronic acid phosphate disclosed by the invention can be used for preparing medicines, food or functional products with immunological enhancement.

The invention relates to a traditional Chinese medicine enteric-coated tablet for treating immunodeficiency and belongs to a Chinese patent medicine for treating immunodeficiency. The traditional Chinese medicine enteric-coated tablet has a better treatment effect. A preparation method of the traditional Chinese medicine enteric-coated tablet comprises the following steps: extracting and mixing effective components of ginseng, radix astragal, angelica sinensis, bighead atractylodes rhizome, poria cocos, Chinese yam, rhizoma cimicifugae, euphorbia pekinensis, radix kansui, coptis chinensis and jujubes and protein power to be put into the enteric-coated tablet. As long as an immunodeficiency patient takes the enteric-coated tablet on time by dosage at different onset stages, both the appetite and the physical fitness can be restored, and the resistance can be enhanced.

The invention relates to a method for producing myocardial cells through differentiation induction of iPSC (induced pluripotent stem cells). Specifically, LAA is added in the differentiation process to improve the cell viability and the myocardial cell conversion rate, by means of accurate adjustment of an agonist CHIR99021 and an inhibitor IWR-1 of a Wnt / beta-catenin signal channel, continuous activation of the Wnt signal channel is maintained in the early stage to enable iPSC to be stably converted into mesoderm cells, the success rate of myocardial differentiation is improved, and finally, the success rate of myocardial differentiation is increased. The high-purity myocardial cells are obtained through treatment of a sugar-free purification reagent. The method for differentiating the myocardial cells from the iPSC is high in universality and repeatability, can be well applied to a disease source difficult to differentiate or an iPSC cell line subjected to gene editing, and can be widely applied to the field of myocardial cell differentiation. And the obtained high-purity myocardial cells can be widely applied to heart safety evaluation of drugs, high-throughput screening of cardiovascular treatment drugs, and application of the myocardial cells as 2D and 3D research models of cardiovascular diseases to cardiovascular pathogenesis research.

The invention discloses the application of the hepcidin antagonist LDN193189 and its derivatives in the preparation of medicines, belongs to the field of medical technology, and provides the application of the hepcidin antagonist LDN193189 and its derivatives in the preparation and treatment of bone marrow type acute radiation sickness and radiotherapy-induced blood cell drop New uses of applications in disease medicine. Intraperitoneal injection of lethal doses of irradiated mice with LDN193189 and its derivatives can increase the survival rate of irradiated mice to 40% (120 days), and the number of peripheral blood leukocytes and lymphocytes increased significantly; The number of cells was significantly restored; the survival rate of splenic lymphocytes was significantly restored; the number of splenic lymphocytes was significantly increased (HE section). LDN193189 and its derivatives have a good effect on the treatment of bone marrow type acute radiation sickness and radiotherapy-induced cytopenia.

The invention discloses a capsule for treating acquired immune deficiency syndrome, and belongs to a prepared Chinese medicine capable of effectively treating acquired immune deficiency syndrome. The preparation method of the capsule comprises the following steps: extracting effective constituents of codonopsis pilosula, angelica sinensis, astragalus membranaceus, atractylodes macrocephala, wolfiporia cocos, prepared euphorbia pekinensis, euphorbia kansui, ziziphus zizyphus and coptis chinensis and mineral resource fulvic acid and albumen powder, and then loading the effective constituents, the mineral resource fulvic acid and the albumen powder into a capsule. If only taking the capsule periodically at proper does according to different accession time, acquired immune deficiency syndrome patients can recover appetite, physical ability and work ability.

The invention discloses morchella polysaccharide and application of degraded morchella polysaccharide in prevention and treatment of ulcerative colitis. The degraded morchella esculenta polysaccharide is obtained by degrading the morchella esculenta polysaccharide by adopting an ultrasonic combined H2O2-VC method. The morchella esculenta polysaccharide or degraded morchella esculenta polysaccharide slows down weight loss and colon length shortening of a patient, improves colon pathological conditions, reduces the oxidative stress level of the patient, reduces the MDA content in colon tissue of the patient, enhances the vitality of CAT, SOD and GSH, and can be used for preventing and treating the disease of the patient. According to the present invention, with the application of the traditional Chinese medicine composition, the secretion level and the gene expression level of IL-1beta, IL-6 and TNF-alpha can be reduced, the secretion level and the gene expression level of IL-10 can be improved, the damage of intestinal barrier cells caused by DSS can be repaired, the number of goblet cells can be increased, the infiltration of inflammatory cells can be reduced, the richness of intestinal flora can be improved, the dominant bacteria can be increased, the harmful bacteria can be reduced, and the recovery of intestinal flora can be promoted; the invention provides a novel medicine for preventing and treating ulcerative colitis.

The invention discloses a medicament for remediating polluted soil and a preparation method thereof. The present invention consists of 5 to 100 parts of microbial agents and 1 to 200 parts of chemical agents in parts by weight; microbial agents include indigenous microbial cultures, nitrifying bacteria cultures, denitrifying bacteria cultures, and phosphorus accumulating bacteria The weight ratio of the culture of bacteria, yeast culture, lactic acid bacteria, indigenous microorganism culture, nitrifying bacteria culture, denitrifying bacteria culture, phosphorus accumulating bacteria culture, yeast culture, and lactic acid bacteria culture is 5 to 10: 10~15: 10~15: 5~10: 10~15, 5~10; chemical agents include heavy metal deactivator and curing agent, the weight ratio of heavy metal deactivator and curing agent is 1‑30: 3‑170 . The invention adopts the combined physical-chemical-biological treatment technology to treat the polluted soil, and the invention has a good restoration effect on the polluted soil.

The invention discloses applications of Baweixihonghua bleeding stopping powder in preparation of leukopenia treatment drugs, and belongs to the field of medicine. According to the present invention, the technical bias of the Baweixihonghua bleeding stopping powder in the application field is overcome; and the animal research results show that the leukopenia caused by conventional radiotherapy and chemotherapy can be significantly improved (P<0.05) with the Baweixihonghua bleeding stopping powder, the number of the bone marrow nucleated cell can be restored, the effect of the Baweixihonghua bleeding stopping powder is equivalent to the effect of the traditional leucocyte increasing drug batyl alcohol, and the Baweixihonghua bleeding stopping powder can be used to prepare the leukopenia treatment drug.

The invention discloses an application of a brassica napus BnaSPT3 gene in promoting growth of pods of dicotyledons. A base sequence of the brassica napus BnaSPT3 gene is shown as SEQ ID NO.1. The application comprises the following steps: (1) linking the brassica napus BnaSPT3 gene into a plant expression vector, so that a recombinant expression vector is constructed; and (2) transforming the recombinant expression vector into a recipient plant. The invention also discloses the recombinant expression vector containing the brassica napus BnaSPT3 gene and a transformant containing the recombinant expression vector. According to the application provided by the invention, by cloning the brassica napus BnaSPT3 gene, implementing genetic transformation in arabidopsis thaliana and through excessive expression of the exogenous brassica napus BnaSPT3 gene, the size of arabidopsis thaliana spt mutant pods can be obviously increased, and the number of seeds can be recovered. On the basis of genetic engineering technology, over-expression of the brassica napus BnaSPT3 gene in a receptor is achieved, and the size of the pods is changed; therefore, the invention is conducive to high-yield researches.