The invention relates to the field of compound fertilizers, and particularly relates to a double slow-release compound fertilizer containing herba houttuyniae. The fertilizer is prepared from the following raw materials in parts by weight: 10-15 parts of kieselguhr of 1250-2000 meshes, 6-8 parts of potassium benzoate, 10-12 parts of heavy calcium carbonate, 15-18 parts of ammonium hydrogen carbonate, 4-6 parts of boric acid, 18-20 parts of dried cow dung, 10-12 parts of tobacco waste, 20-22 parts of rotted mushroom mash, 4-5 parts of papain, 2-3 parts of fish viscera dried powder, 1-2 parts of herba houttuyniae powder, 8-10 parts of wheat bran, 6-8 parts of dialdehyde starch, 4-5 parts of glycerol, 3-6 parts of sodium alginate, 1-2 parts of potassium ferrocyanide, 10-12 parts of vinyl acetate, 0.2-0.3 part of ammonium persulfate, 1-2 parts of sodium dodecylsulfate, 2-4 parts of medical stone powder, 6-8 parts of 50-60% sulfuric acid and 4-5 parts of assistant. According to the invention, the compound fertilizer contains diverse raw materials and multiple nutrients; double coating is formed by using the kieselguhr and the slow-release coating agent containing the herba houttuyniae, so that the nutrients are less prone to loss, and the fertilizer efficiency can last longer. The compound fertilizer can improve the antimicrobial and disease-resistant capabilities of crops without destroying the ecological environment of soil, and the yield and quality of the crops can be improved.