Plant essential oil microemulsion gel as well as preparation method and application thereof

A technology of microemulsion gel and plant essential oil, which is applied to plant raw materials, medical raw materials derived from gymnosperm subphylum, plant/algae/fungus/moss components, etc., can solve problems such as no application reports, and achieve widening options Scope, good bacteriostatic effect and simple processing technology

Active Publication Date: 2016-12-07
湖南仁馨生物技术有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] There are no reports on the application of plant essential oil compound microemulsion gel in the treatment of bacterial and fungal dermatitis and other skin diseases.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] The present embodiment provides a plant essential oil microemulsion gel, and the specific steps are as follows:

[0031] (1) Soak 0.5g Carbomer-940 in 50g water for 12h;

[0032] (2) Use 50g of water to mix well with cinnamon oil (1g), clove basil oil (1g), turpentine oil (1g) and glycerin (2g), and add 0.2g of polyethylene glycol 400 at the same time, stir until no layering Add tea polyphenols 0.01g;

[0033] (3) Mix the solutions in step (1) and step (2), and keep stirring, add 0.05 g of sodium dodecylbenzenesulfonate and 0.05 g of PVP (K30) at the same time, and stir until they are uniform without stratification;

[0034] (4) Add 0.05 g of peppermint leaf extract to the solution in step (3);

[0035] (5) Add 0.05 g of lactic acid to the mixture in step (4), and stir evenly.

Embodiment 2

[0037] The present embodiment provides a plant essential oil microemulsion gel, and the specific steps are as follows:

[0038] (1) Soak 1g Carbomer-940 in 50g water for 12h;

[0039] (2) Use 50g of water to mix well with cinnamon oil (5g), clove basil oil (5g), turpentine oil (5g) and glycerin (2g), and add 0.2g polyethylene glycol 400 at the same time, stir until no layering Add tea polyphenols 0.03g.

[0040] (3) Mix the solutions in step (1) and step (2), and keep stirring, add 0.05 g of sodium dodecylbenzenesulfonate and 0.05 g of PVP (K30) at the same time, and stir until they are uniform without stratification;

[0041] (4) Add 0.15 g of peppermint leaf extract to the solution in step (3);

[0042] (5) Add 0.1 g of lactic acid to the mixture in step (4), and stir evenly.

Embodiment 3

[0044] The present embodiment provides a plant essential oil microemulsion gel, and the specific steps are as follows:

[0045] (1) Soak 0.8g Carbomer-940 in 50g water for 12h;

[0046] (2) Mix 50g of water with cinnamon oil (3g), clove basil oil (3g), turpentine oil (3g) and glycerin (2g) and mix well, add 0.2g polyethylene glycol 400 at the same time, stir until no layering Add tea polyphenols 0.02g;

[0047] (3) Mix the solutions in step (1) and step (2), and keep stirring, add 0.05 g of sodium dodecylbenzenesulfonate and 0.05 g of PVP (K30) at the same time, and stir until they are uniform without stratification;

[0048] (4) Add 0.1 g of peppermint leaf extract to the solution in step (3);

[0049] (5) Add 0.08 g of lactic acid to the mixture in step (4), and stir evenly.

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PUM

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Abstract

The invention provides a plant essential oil microemulsion gel as well as a preparation method and an application thereof. The microemulsion gel consists of plant essential oil and adjuvant materials, wherein in parts by weight, the plant essential oil includes 1-5 parts of cinnamon oil, 1-5 parts of ocimi gratissimi oil and 1-5 parts of turpentine oil. The microemulsion gel provided by the invention, which is used for treating bacterial and fungal dermatitis, is prepared from the natural plant essential oil by taking carbomer as a substrate. The microemulsion gel is natural in raw material source and low in cost, and the prepared microemulsion gel is good in antibacterial effect, simple in processing technique, low in cost and basically free from toxic and side effects; and the prepared microemulsion gel has a good therapeutic effect.

Description

technical field [0001] The invention relates to a plant essential oil microemulsion gel and a preparation method and application thereof, belonging to the technical field of medical dressings. Background technique [0002] The development of external dressings for skin treatment is very rapid, but there are still some limitations, especially in the selection of antibacterial agents. Since antibiotics are easy to induce drug resistance in the body, the development of new antibacterial agents has become a hot spot in recent years. Natural antibacterial substances such as chitosan are mainly suitable for cases with a low degree of infection; other antibacterial agents currently used such as nano-silver and silver sulfadiazine TiO2 have strong antibacterial ability, but they all have certain cytotoxicity. Slow-release measures such as embedding can reduce its cytotoxicity to a certain extent, but how to further improve the preparation method, so that the antibacterial agent can ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/107A61K9/06A61K47/32A61K36/54A61K36/82A61P17/00A61P31/04A61P31/10A61K31/353
CPCA61K9/0014A61K9/06A61K9/1075A61K31/353A61K36/15A61K36/53A61K36/534A61K36/54A61K36/82A61K47/32A61K2300/00
Inventor 周波李远梅
Owner 湖南仁馨生物技术有限公司
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