Cornea decellularization system

A decellularization and cornea technology, applied in the field of corneal decellularization, can solve the problems of limiting the large-scale production and application of cornea, small processing volume and high cost

Active Publication Date: 2017-01-04
SHENZHEN AINEAR CORNEA ENG
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Problems solved by technology

[0004] The current research and development and production of corneal substitutes are all completed in the reaction bottle by shaking on a shake

Method used

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Embodiment Construction

[0039] The following will clearly and completely describe the technical solutions in the embodiments of the present invention with reference to the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only some, not all, embodiments of the present invention. Based on the embodiments of the present invention, all other embodiments obtained by persons of ordinary skill in the art without making creative efforts belong to the protection scope of the present invention.

[0040] In describing the present invention, it is to be understood that the terms "center", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", The orientations or positional relationships indicated by "top", "bottom", "inner", "outer", etc. are based on the orientations or positional relationships shown in the drawings, and are only for the convenience of describing the present invention and simplifying the description, rather than in...

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Abstract

The invention relates to the technical field of cornea decellularization, particularly a cornea decellularization system. The cornea decellularization system can perform mass treatment on the premise of ensuring the cornea decellularization quality, is convenient to use and low in cost, and creates conditions for large-scale production and application of the corneas. The cornea decellularization system overcomes the defects of small mass treatment capacity, higher cost and difficulty in implementing large-scale production and application of corneas in the prior art. The cornea decellularization system provided by the embodiment of the invention comprises a decellularization facility, an oscillation facility, a decellularization reagent tank and an injection water tank, wherein the decellularization facility comprises a reaction tank; the oscillation facility is arranged on the lower part of the reaction tank, and used for diving the reaction tank to oscillate; and the decellularization reagent tank and the injection water tank are used for alternately supplying a decellularization agent and injection water into the reaction tank; and the reaction tank is used for carrying out decellularization treatment on the animal corneas to obtain the decellularized corneas.

Description

technical field [0001] The invention relates to the technical field of corneal decellularization, in particular to a corneal decellularization system. Background technique [0002] Corneal disease is the second most common cause of blindness after cataract. Due to the severe shortage of human corneal donors, the main treatment for corneal disease is allogeneic corneal transplantation. Therefore, seeking suitable corneal substitutes has great medical value for corneal transplantation. . For a long time, people have been committed to the development of corneal substitutes with good biocompatibility, low immunogenicity, and good repair effect after eye implantation. After research, people found that high molecular polymers have low biocompatibility and good mechanical properties. However, due to the disadvantage of poor control, it cannot meet the needs of corneal treatment. [0003] In recent years, with the development of decellularization technology, researchers have found...

Claims

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Application Information

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IPC IPC(8): A61L27/36A61F2/14
Inventor 王维博李辉张晋南张爱兵张斌
Owner SHENZHEN AINEAR CORNEA ENG
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