Organic quick drying mounting medium

A sealing tablet and quick-drying technology, applied in the field of biomedical applications, can solve the problems of easy fading of tissue slices, poor refraction and transparency, and fluctuation of product pH, etc., and achieve the effects of shortening drying time, preserving color, and sticking firmly.

Inactive Publication Date: 2017-02-01
宁波同盛生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] There are many disadvantages in the existing traditional tissue section mounting agent: it takes a long time to dry and stick the slide glass and cover glass firmly, about 1 month; The solid solute of the traditional mounting agent is acidic, which must be neutralized during the preparation process, which will easily lead to fluctuations in the pH of the product, which in turn will cause tissue sections to fade easily after dyeing during storage, which is not conducive to the quality of the slices long-term maintenance

Method used

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  • Organic quick drying mounting medium

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Embodiment 1

[0013] Embodiment 1: The first specific embodiment of the organic quick-drying sealing agent of the present invention. An organic quick-drying mounting agent, the mounting agent comprising the following components: 60% by volume of xylene, 18.5% by volume of toluene, and 21.5% by volume of polyisobutyl methacrylate.

[0014] The preparation method of the organic quick-drying sealing tablet comprises the steps of: taking an appropriate amount of xylene, toluene and polyisobutyl methacrylate in proportion and adding it to a sealed container, mixing until the isobutyl methacrylate is completely dissolved, and subpackaging the finished product for preservation , to obtain an organic quick-drying mounting tablet.

[0015] The organic quick-drying mounting agent of the present invention can effectively shorten the drying time of the slices, and the slices are completely dried 3 days after the mounting, and the cover glass is firmly pasted. Organic quick-drying sealing agent (Exampl...

Embodiment 2

[0019] Embodiment 2: Organic quick-drying mounting agent, described mounting agent comprises following component: the xylene of 75% volume ratio, the toluene of 5% volume ratio, the polyisobutyl methacrylate of 20% volume ratio, other With embodiment 1.

Embodiment 3

[0020] Embodiment 3: organic quick-drying mounting agent, described mounting agent comprises following component: the xylene of 50% volume ratio, the toluene of 30% volume ratio, the polyisobutyl methacrylate of 20% volume ratio, other With embodiment 1.

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Abstract

The invention discloses an organic quick drying mounting medium and belongs to the technical field of biomedical application. The mounting medium is prepared from the following components: 50 to 80 volume percent of dimethylbenzene, 5 to 30 volume percent of methylbenzene and 20 to 30 volume percent of isobutyl methacrylate. Compared with the prior art, the organic quick drying mounting medium disclosed by the invention has the advantages that the drying time of a section can be effectively shortened, cover glass is firmly stuck, and colloid of the mounting medium is colorless and transparent; the refraction performance of the organic quick drying mounting medium is remarkably superior to that of a traditional mounting medium; a PH value is neutral and ionization is avoided; after mounting, dye molecules in the section does not generate reaction, so that the color of tissue sections can be effectively kept for a long time.

Description

technical field [0001] The invention belongs to the technical field of biomedical application, in particular to an organic quick-drying sealing tablet. Background technique [0002] Sealing is to seal and store tissue sections (also blood smears, cell slides, etc.) between the slide glass and the cover glass, so that they do not come into contact with the air, prevent their oxidation and fading, and facilitate microscopic observation. and save. For tissue sections, after staining, after dehydration and transparency, in order to be easy to observe under a microscope and to preserve for future reference, it is necessary to seal the stained slices with a mounting agent (also known as mounting agent, mounting medium, etc.). Thereby completing the making of a tissue slide specimen. In general, a better mounting agent has the following characteristics: 1. Strong viscosity; 2. Better refractive properties; 3. The difference between the refractive index and the glass slide is not ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N1/36C08J3/11C08L33/10
CPCG01N1/36C08J3/092C08J3/11C08J2333/10
Inventor 王华林益禾
Owner 宁波同盛生物科技有限公司
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