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Application of root of large-flowered skullcap to preparation of drug used for inhibiting peristalsis of recta

A rectal administration and drug technology, applied in the field of medicine, can solve the problems of easy allergies, unobstructed urination, incompatibility of patients, etc., and achieve the effects of inhibiting rectal peristalsis, normal urination and defecation, and easy availability of raw materials

Inactive Publication Date: 2017-07-11
查奇士
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] The invention discloses a new use of Scutellaria baicalensis, namely the application in the preparation of medicines for inhibiting rectal peristalsis, which solves the problems in the prior art that the use of chemical drugs to inhibit rectal peristalsis makes patients prone to allergies, urination is not smooth, and the problems of incompatibility with other medicines

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] Prepare powders.

[0026] Composition: Scutellaria baicalensis

[0027] Preparation method: take Scutellaria baicalensis, crush, pass through an 80-mesh sieve, and sterilize. Use 2-5g each time.

Embodiment 2

[0029] Prepare decoction.

[0030] Composition: Scutellaria baicalensis

[0031] Preparation method: Take 100g of Scutellaria baicalensis and add water to decoct three times, add 500ml of water each time, decoct for 30 minutes each time, combine the decoction, filter, and concentrate the filtrate to 400ml. Use 10-20ml each time.

Embodiment 3

[0033] Clinical application of the present invention.

[0034] Patient 1, Xu, female, 53 years old, visited the doctor on January 4, 2017.

[0035] History of present illness: morning stiffness for 1 year, limb joint pain for 4 years.

[0036] Examination: the general condition is acceptable, the tonsils are not enlarged, the abdomen is soft, no tenderness, there is tenderness at the joints of the extremities, no deformation, no enlargement.

[0037] Stool history: Stool twice a day within three months, once in the morning and once in the afternoon.

[0038] Diagnosis: rheumatoid arthritis.

[0039] Method for the treatment of: anti-rheumatic, pain relieving.

[0040] Treatment: Zushima injection 6ml, compound angelica injection 6ml, bone peptide injection 4ml, compound ammonin barbiturate injection 4ml, traditional Chinese medicine Scutellaria baicalensis powder 2g, rectal injection, once a day.

[0041] Operation method: Put 6ml of Zushima injection, 6ml of compound ange...

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PUM

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Abstract

The invention discloses novel application of the root of large-flowered skullcap, i.e., application of the root of large-flowered skullcap to preparation of a drug used for inhibiting peristalsis of recta. In the prior art, when a drug is injected via the rectum, the rectum suffers from stimulation and peristalsis of the intestines is increased, so the injected drug is discharged out of the body, which leads to influence on the curative effect of the drug; and the application of the root of large-flowered skullcap disclosed in the invention can overcome the above problem. The root of large-flowered skullcap has definite effect on inhibition of the peristalsis of recta, can prolong the retention time of drugs in the intestines and is safe and effective.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to the application of Scutellaria baicalensis in the preparation of medicines for inhibiting rectal peristalsis. Background technique [0002] Rectal administration refers to the method of delivering drugs into the intestinal tract through the anus, and enters the large circulation through the rapid absorption of the rectal mucosa, and exerts the drug effect to treat systemic or local diseases. Rectal administration is simple and easy, and has high bioavailability. Clinically, rectal injection and infusion of liquid drugs are commonly used to treat diseases. However, when the drug is injected, it will stimulate the rectum, thereby increasing intestinal peristalsis, and causing the liquid drug injected into the body to be excreted, thereby affecting the efficacy of the drug. [0003] In the prior art, lidocaine and anisodamine are often injected through the rectum to in...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/539A61K47/46A61K125/00
Inventor 查奇士
Owner 查奇士
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