Application of rhizoma coptidis to preparing medicines for inhibiting rectal peristalsis

A drug, Coptis chinensis technology, applied in the field of medicine, can solve the problems of rectal irritation, increase intestinal peristalsis, affect the efficacy of drugs, etc., and achieve the effects of increasing absorption, prolonging residence time, and inhibiting rectal peristalsis.

A drug, Coptis chinensis technology, applied in the field of medicine, can solve the problems of rectal irritation, increase intestinal peristalsis, affect the efficacy of drugs, etc., and achieve the effects of increasing absorption, prolonging residence time, and inhibiting rectal peristalsis.

CN106511515AInactive Publication Date: 2017-03-22查奇士
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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] Prepare powder.

[0021] Composition: Coptis

[0022] Preparation method: Take Rhizoma Coptidis, pulverize, pass through an 80-mesh sieve, and sterilize to get it. Use 1-5g each time.

Embodiment 2

[0024] Clinical application of the present invention.

[0025] Patient 1, Liu Mou, male, 6 years old, presented to the doctor on November 26, 2016.

[0026] History of present illness: Long-term repeated colds with cough for 2 days.

[0027] Check: The general condition is fair, the tonsils are not enlarged, the heart and lungs are normal, the abdomen is soft and not tender, and the rest are normal.

[0028] Stool history: Stool once a day in a month.

[0029] Diagnosis: Deficiency of lung qi, cough due to external symptoms.

[0030] Treatment: Strengthen immunity, invigorate lung and qi, relieve cough and resolve phlegm.

[0031] Treatment: Yupingfeng oral liquid 10ml, Houttuynia cordata injection 2ml, transfer factor capsule 6mg, Shedan Chenpi capsule 0.3g, vitamin B6 injection 0.1g, rectal injection, once a day.

[0032] Operation method: Put 10ml of Yupingfeng Oral Liquid, 2ml of Yuxingcao Injection, 6mg of Transfer Factor Capsule Content, 0.3g of Shedan Chenpi Capsule, and 0.1g of Vit...

Embodiment 3

[0043] Clinical application of the present invention.

[0044] Patient 2, Luo Mou, male, 4 years old, saw a doctor on December 6, 2016.

[0045] History of present illness: Cough for 4 days, severe cough at night and morning, dry cough without sputum.

[0046] Inspection: Normal condition, no enlarged tonsils, rough breath sounds in both lungs, phlegm sounds can be heard in the lungs, normal heart sounds, soft abdomen, no tenderness, and other normal.

[0047] Stool history: stool once a day within six months.

[0048] Diagnosis: bronchitis.

[0049] Treatment: anti-infection, anti-virus, relieving cough, resolving phlegm and relieving asthma.

[0050] Treatment: skin test (-), ceftriaxone sodium for injection 1.0g, ketotifen fumarate tablets 1mg, ribavirin injection 0.1g, shedan tangerine peel capsule 0.3g, compound folcodine oral solution 10ml, Vitamin B6 injection 0.1g, azithromycin dispersible tablets 0.25g, 0.9% sodium chloride injection 5ml, rectal injection, once a day.

[0051] Op...

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Abstract

The invention discloses novel application of rhizoma coptidis, and discloses application of rhizoma coptidis to preparing medicines for inhibiting rectal peristalsis. By the aid of the application, the problem of influence on curative effects of medicines due to the fact that rectums can be irritated when the medicines are injected into the rectums, intestine peristalsis can be improved and the liquid medicines injected into human bodies can be drained out of the human bodies in the prior art can be solved. The application has the advantages that definite effects of inhibiting the rectal peristalsis can be realized, the residence time of the medicines in intestinal tracts can be prolonged, and the medicines are safe and effective.

Description

Technical field [0001] The invention belongs to the technical field of medicine, and specifically relates to the application of Coptis in the preparation of drugs for inhibiting rectal peristalsis. Background technique [0002] Rectal administration is simple and easy, with high bioavailability. In clinical practice, rectal bolus injection and drip infusion are commonly used to treat diseases. However, the injection of drugs will cause irritation to the rectum, increase intestinal peristalsis, and excrete the injected drugs from the body, thereby affecting the efficacy of the drugs. [0003] Coptis chinensis is the dried rhizome of Coptis chinensis Franch. Coptis chinensis Franch., Coptis deltoidea C.Y. Cheng et Hsiao or Coptis teeta Wall. It contains a variety of alkaloids and has the functions of clearing heat and dampness, purging fire and detoxification. Summary of the invention [0004] The invention discloses the new use of Coptis chinensis, that is, its application in the pr...

Claims

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Application Information

Patent Timeline
22 Mar 2017
Publication
CN106511515A
IPC
A61K36/718; A61P1/00
CPC
A61K9/0031; A61K36/718
Inventors
查奇士