Application of alpha-mangostin to preparation of medicine for treating autoimmune disease
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- SUN YAT SEN UNIV
- Publication Date
- 2017-08-08
- Estimated Expiration
- Not applicable · inactive patent
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Abstract
Description
technical field
[0001] The invention relates to a new application of α-mangostin, in particular to the application of α-mangostin in the preparation of medicines for treating autoimmune diseases. Background technique
[0002] About 5% of the population suffers from autoimmune diseases, and more than 70 human diseases are related to autoimmune disorders (Goodnow et al., 2005). At present, the treatment of autoimmune diseases mainly relies on some non-selective immunosuppressants, which have limited curative effect and large side effects. There is no very effective drug for the treatment of autoimmune diseases in clinical practice. Therefore, there is an urgent need to develop a new type of autoimmune drug with high efficacy and low side effects.
[0003] The latest research shows that Th17 cells, a new T cell subset, are closely related to the occurrence of human autoimmune diseases and related animal models (Kikly et al., 2006). In autoimmune diseases such as rheumatoid ar...