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Application of fatty oil in diarrhea-stopping formula to preparation of infantile diarrhea treating navel patch

A technology for infantile diarrhea and fat oil, applied in the field of pharmaceutical preparations, can solve the problems of reducing drug efficacy and waste of material resources

Active Publication Date: 2017-11-03
张军
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The inventor later discovered that the fat oil in the formula of amomum seed, herb, cinnamon and clove not only has good curative effect on infantile diarrhea, but also has a synergistic effect when mixed with its volatile oil. Therefore, the fat oil in the formula Abandoning the oil obviously not only caused a waste of material resources, but also reduced the efficacy of the medicine.

Method used

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  • Application of fatty oil in diarrhea-stopping formula to preparation of infantile diarrhea treating navel patch
  • Application of fatty oil in diarrhea-stopping formula to preparation of infantile diarrhea treating navel patch
  • Application of fatty oil in diarrhea-stopping formula to preparation of infantile diarrhea treating navel patch

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0077] 1. Prescription: Amomum 1500g, Atractylodes 2700g, cinnamon 1350g, clove 375g.

[0078] 2. Extract volatile oil and fatty oil:

[0079] (1) Extraction of volatile oil by steam distillation: crush the raw material drug, pass through a 24-mesh sieve, add 15 times the amount of water and soak for 30 minutes, extract by steam distillation, collect the oil layer, and obtain the volatile oil;

[0080] (2) Petroleum ether extraction of fatty oil: After filtering the medicinal residues obtained by extracting the volatile oil by steam distillation, dry, pulverize, and pass through a 40-mesh sieve; On the generator, ultrasonically extract for 30 minutes, filter, and recover the solvent to obtain the fatty oil.

[0081] 3. Supercritical CO 2 Extraction of volatile and fatty oils:

[0082] Get the raw material medicine, pulverize No. 2 sieve, supercritical CO 2 Extraction, the extraction pressure is 28Mpa, the extraction temperature is 45°C, the pressure of analysis Ⅰ and Ⅱ is ...

Embodiment 2

[0091] 1. Prescription: Amomum 1585g, Atractylodes 2613g, cinnamon 1333g, clove 394g.

[0092] 2. Extract volatile oil and fatty oil:

[0093] Extraction method is identical with embodiment 1.

[0094] 3. Supercritical CO 2 Extraction of volatile and fatty oils:

[0095] Extraction method is identical with embodiment 1.

[0096] 4. Preparation of ointment:

[0097] (1) Preparation of navel patch Ⅰ:

[0098] Take an appropriate amount of 40-type fatty acid glyceride, put it in a water bath at 50°C, and bathe until it melts; add the fatty oil extracted in the above step 2, stir well, and make 1500g to obtain ointment; press 1.0g / paste ointment while it is hot Spread it on the leak-proof ring of the blank plaster, after cooling, cover it with an anti-adhesive layer to make a belly button patch.

[0099] (2) Preparation of Navel Sticker II:

[0100] Take an appropriate amount of 40-type fatty acid glyceride, put it in a water bath at 50°C, and bathe until it melts; add the ...

Embodiment 3

[0104] 1. Prescription: Amomum 1489g, Atractylodes 2782g, cinnamon 1322g, clove 332g.

[0105] 2. Extract volatile oil and fatty oil:

[0106] Extraction method is identical with embodiment 1.

[0107] 3. Supercritical CO 2 Extraction of volatile and fatty oils:

[0108] Extraction method is identical with embodiment 1.

[0109] 4. Preparation of ointment:

[0110] (1) Preparation of navel patch Ⅰ:

[0111] Take an appropriate amount of 40-type fatty acid glyceride, put it in a water bath at 50°C, and bathe until it melts; add the fatty oil extracted in the above step 2, stir well, and make 1500g to obtain ointment; press 1.0g / paste ointment while it is hot Spread it on the leak-proof ring of the blank plaster, after cooling, cover it with an anti-adhesive layer to make a belly button patch.

[0112] (2) Preparation of Navel Sticker II:

[0113] Take an appropriate amount of 40-type fatty acid glyceride, put it in a water bath at 50°C, and bathe until it melts; add the ...

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Abstract

The invention relates to the application of fatty oil in a diarrhea-stopping formula to the preparation of an infantile diarrhea treating navel patch. The diarrhea-stopping formula comprises the following medicinal raw materials in percent by weight: 23-28% of fructus amomi, 41-50% of rhizoma atractylodis, 20-25% of cinnamon and 5.6-7% of clove. The fatty oil in the diarrhea-stopping formula not only has a very good therapeutic effect for infantile diarrhea, but also has a synergistic effect after being mixed with volatile oil in the diarrhea-stopping formula, so that through the application of the fatty oil, material resources can be saved and the medicinal effect can be significantly improved.

Description

technical field [0001] The present invention relates to a pharmaceutical preparation with an undetermined structure from plants, in particular to an organic compound with a long aliphatic hydrocarbon chain containing a carboxyl group at one end, and the organic compound has biological activity for treating diarrhea. Background technique [0002] Vegetable oil is a compound composed of unsaturated fatty acid and glycerol. It is widely distributed in nature and is the oil obtained from the fruit, seed and germ of plants. Volatile oil, also known as essential oil, is a general term for a class of volatile oily components present in plants that have an aromatic odor, can be distilled with water vapor, and are immiscible with water. Volatile oil is a mixture with complex components. The essential oil is mainly obtained by steam distillation. Among the volatile oil components, terpenes are more common. The pharmacological activities of volatile oils in plants have been widely r...

Claims

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Application Information

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IPC IPC(8): A61K36/9064A61P1/12C11B1/10C11B9/02
CPCA61K36/284A61K36/54A61K36/61A61K36/9064A61K2236/35A61K2236/37C11B1/106C11B9/027A61K2300/00
Inventor 张军刘宇杨蕊叶炳皇姚黎明刘坚初
Owner 张军
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