Oil-based concentrated solution, preparation method and application thereof

A concentrated liquid, oil-based technology, applied in the field of pesticides, can solve the problems of limited solubility and solubility of spirotetramat and pyriproxyfen, difficult to prepare high-content compound preparations, and high processing equipment requirements, and achieve control The effect of particle size growth problem, excellent stability, low equipment requirements

Pending Publication Date: 2017-12-08
JIANGSU ROTAM CHEM
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In the actual preparation process, the above dosage forms will encounter more or less difficulties
For example, because the melting point of pyriproxyfen is 45-47°C, the preparation of wettable powder, water dispersible granule or suspension will be unsuitable or impossible to process because the melting point is too low, and the products prepared from the above preparations will be stored at 54°C. The product fails due to the melting of the original drug, which is theoretically not feasible
Although it is theoretically feasible to prepare microcapsule suspensions and microcapsule suspensions-suspension concent

Method used

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  • Oil-based concentrated solution, preparation method and application thereof
  • Oil-based concentrated solution, preparation method and application thereof
  • Oil-based concentrated solution, preparation method and application thereof

Examples

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Embodiment 1

[0071] In this example, the oil-based concentrate includes the following components:

[0072]

[0073]

[0074] The preparation method is as follows: add pyriproxyfen into ethyl oleate, stir fully to completely dissolve pyriproxyfen in ethyl oleate. Add other materials into the above mixture in any order, and stir evenly to obtain a suspension. Under 45°C, through a sand mill for primary coarse grinding and secondary fine grinding, an oil-based concentrate with a suspended particle D90 of less than 5 μm is obtained.

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PUM

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Abstract

The invention discloses an oil-based concentrated solution, a preparation method and application thereof. The oil-based concentrated solution comprises the following components: (a) at least one active spirotetramat matter which is solid under room temperature, (b) at least one active pyriproxyfen matter which is solid under room temperature, (c) at least one aliphatic ester with the formula R1-COO-R2 and/or R1-COO-R2-OOC-R1, (d) at least one nonionic surfactant and/or at least one anionic surfactant and (e) one or at least two additives randomly selected from an emulgator, a de-foaming agent, a preservative, an antioxidant, a colorant or inertial filling material, wherein pyriproxyfen is dissolved in the component c under molecular state and spirotetramat is suspended in the component c under particle state. The oil-based concentrated solution prepared according to the invention is capable of effectively controlling the problem of grain size increasing of spirotetramat in a storage process, promoting the preparation stability, enhancing the compounding effect and enhancing the bioavailability.

Description

technical field [0001] The invention belongs to the field of pesticides, and relates to an oil-based concentrated liquid and its preparation method and application. Background technique [0002] Spirotetramat is a tetronic acid compound developed by Bayer, and it is one of the modern insecticides with two-way systemic conduction performance. The compound can move up and down throughout the plant to reach the foliage and bark, thereby controlling pests such as on the inner leaves of lettuce and cabbage and on the bark of fruit trees. This unique systemic property protects young stems, leaves and roots from the growth of pest eggs and larvae. Another feature is its long-lasting effect, which can provide effective control for up to 8 weeks. [0003] Pyriproxyfen is an insect growth regulator that disrupts the growth of insects with phenyl ethers. It is a new type of insecticide that is similar to juvenile hormones. It has systemic transfer activity, low toxicity, and long-las...

Claims

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Application Information

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IPC IPC(8): A01N47/06A01N43/40A01N25/04A01N25/30A01P7/04
CPCA01N25/04A01N25/30A01N43/40A01N47/06
Inventor 吴一凡
Owner JIANGSU ROTAM CHEM
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