Multi-property imaging method of biological tissue based on acoustoelectric effect and acoustic radiation force

Abstract

The invention relates to a biological tissue multi-characteristic imaging method based on the acoustoelectric effect and acoustic radiation force. The method comprises the steps that the size of the focal spot of each focusing domain of an ultrasonic transducer under a focusing ultrasonic disturbance mode is measured, and the sequence that the focusing domains are scanned by focusing ultrasonic waves is determined; a low-intensity tracking pulse is emitted to the ultrasonic transducer, and under the condition that ultrasonic focusing is ignored, a boundary measurement voltage vector phi and anecho signal of the tracking pulse are obtained; when an excitation current reaches the wave peak or the wave trough moment, a high-intensity excitation pulse is emitted to the ultrasonic transducer,so that an emission and scanning mechanism of the ultrasonic transducer works in a focused ultrasonic disturbance mode, and the focusing ultrasonic waves disturb the nth focusing domain; during focusing ultrasonic disturbance, the boundary measurement voltage vector phi n obtained after disturbance is measured, a low-intensity tracking pulse is emitted to the ultrasonic transducer again, and an echo signal is received; an acoustoelectric signal and corresponding displacement information of the nth focusing domain are obtained; the obtained data is processed, and a biological tissue image is reconstructed.

Description

technical field [0001] The invention belongs to the technical field of biological imaging, and relates to an imaging technology for comprehensively analyzing electrical characteristic parameters and elastic characteristics of tissues from two angles of electrical characteristics and mechanical characteristics. Background technique [0002] Ultrasound technology plays an important role in the medical field, and it is widely used in medical diagnosis and detection, medical treatment and surgery. Due to the differences in the elastic mechanical properties of various parts of biological tissues (especially diseased tissues), the responses of the tissues to the applied excitations are also different, mainly manifested in the differences in the distribution of parameters such as displacement, strain, velocity, and shear wave velocity. Therefore, researchers study Ultrasound Elastography on the basis of tissue elasticity theory, wave propagation theory in tissue and signal processi...

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Problems solved by technology

However, many tissue lesions are often accompanied by a variety of phenomena, and these phenomena are not consistent for different tissues, so it is limited to diagnose a single characteristic of the lesion from only one angle.

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