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Precise control method of radio-therapeutic apparatus during adaptive radiotherapy of ocular tumor

A radiotherapy, self-adaptive technology, applied in radiotherapy, X-ray/γ-ray/particle irradiation therapy, treatment and other directions, can solve the problem of eye tumors deviating from the planned position, etc., achieve good social and economic benefits, improve Quality of life, effects of injury prevention

Active Publication Date: 2018-04-06
THE FIRST AFFILIATED HOSPITAL OF WENZHOU MEDICAL UNIV
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Problems solved by technology

[0003] However, due to whether the human eyeball has voluntary movement or not, the position of the eye tumor is also changing all the time, and the radiotherapy plan is designed based on the CT scan at a certain time. At this moment, the positions of the eyeball and the eye tumor are different is fixed, which causes the position of the eye tumor to deviate from the planned position during the actual treatment

Method used

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Embodiment Construction

[0036] The present invention can be better described below in conjunction with specific embodiments.

[0037] A gating method for an accelerator during adaptive radiation therapy for eye tumors, comprising the following steps:

[0038] (1) Conduct CT scan of the eye, and at the same time use OCT to continuously collect eye movement, obtain the displacement parameters caused by eye movement within a certain period of time, and obtain the location of the eye tumor through OCT and CT image registration, and Collect EOG signal caused by eye movement;

[0039](2) Using the amplitude threshold method and the differential method to identify the collected EOG signals and coordinate with the eye movement patterns collected by OCT, through time-weighted analysis, take the displacement parameter as the vertical coordinate and the time as the horizontal coordinate, Obtain a relatively regular motion frequency signal map of eye tumors within a certain period of time, and set the allowable...

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Abstract

The invention relates to a precise control method of a radio-therapeutic apparatus during adaptive radiotherapy of an ocular tumor. An accelerator is gated during adaptive radiotherapy of the ocular tumor; when the position of the ocular tumor is deviated from a planned position, operation of the accelerator is stopped, and damage of radio-therapeutic rays on normal ocular cells is prevented; andwhen the position of the ocular tumor returns to the planned position, operation of the accelerator is recovered, and precise radiotherapy of the ocular tumor is realized. During radiotherapy of the ocular tumor, automatic tracking adaption of a multi-leaf collimator is realized, the multi-leaf collimator can track and adjust the position in real time according to the real-time position of the ocular tumor, and precise adaptive radiotherapy of the ocular tumor is realized. A gated therapeutic system of the ocular tumor and the automatic tracking system of the multi-leaf collimator can be designed and used for precise positioning radiotherapy of the ocular tumor, the social and economical benefit is high, complication of radiotherapy is reduced, and the life quality of patients is improved.

Description

technical field [0001] The invention relates to a precise control method of radiotherapy equipment during adaptive radiotherapy for eye tumors. Background technique [0002] Radiation therapy is one of the important methods for eye tumors, especially for tumors such as choroidal melanoma, retinal glioma, pediatric rhabdomyosarcoma, intraocular lymphoma and uveal melanoma. Give the tumor target area a large enough radiation dose through precise external beam radiation technology, and avoid damage to surrounding normal tissues (optic nerves, spots, ciliary body and crystal) through a steep dose gradient around the tumor, improving the tumor target area. Precise radiation can effectively protect the eyesight of patients with eye tumors and the normal function of the eyeball. [0003] However, due to whether the human eyeball has voluntary movement or not, the position of the eye tumor is also changing all the time, and the radiotherapy plan is designed based on the CT scan at ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61N5/10
CPCA61N5/1017A61N5/1048A61N5/1049A61N5/1071A61N5/1077A61N5/1078A61N2005/1061A61N2005/1092A61N2005/1096
Inventor 金献测谢聪颖沈梅晓
Owner THE FIRST AFFILIATED HOSPITAL OF WENZHOU MEDICAL UNIV
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