Beam shaping body for neutron capture therapy

A body-shaping and neutron technology, applied in the field of neutron capture therapy, can solve the problems of unadjusted and controlled direction, overflow of harmful chemical substances, divergent direction of neutron rays, etc., so as to ensure radiation safety and reduce radiation dose. , the effect of reducing the scattering angle

Pending Publication Date: 2018-05-29
SUNSHINE LAKE PHARM CO LTD +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The neutron beam shaper is the neutron beam generating part in boron neutron capture therapy, which is usually connected with the accelerator and used in boron neutron capture therapy. The existing neutron beam shaper has different risks: on the one hand, neutron The beam exit is open, and there is a risk of harmful rays leaking from the neutron beam exit. At the same time, harmful chemical substances produced during the nuclear reaction may overf

Method used

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  • Beam shaping body for neutron capture therapy
  • Beam shaping body for neutron capture therapy
  • Beam shaping body for neutron capture therapy

Examples

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Embodiment 1

[0050] Such as image 3 and Figure 4 As shown, the beam shaping body for neutron capture therapy according to the embodiment of the present invention includes: a beam passage part 100 , a beam shaping part 200 and a beam shielding part 300 .

[0051] Specifically, the beam passage part 100 includes a beam entrance 110 , a target 120 and a beam exit 130 . The beam passage part 100 is a passage for the beam to run, and the accelerated proton beam enters the beam shaping body from the beam entrance 110, hits the target 120 and undergoes a nuclear reaction to generate neutrons and form a neutron beam It is emitted from the beam exit 130 and reaches the treatment area to perform irradiation treatment on the patient.

[0052] The beam shaping unit 200 includes a beam retarder 210 and a reflector 220 . The beam shaping unit 200 adjusts the neutron beam generated in the target 120 to meet the requirements of neutron capture therapy.

[0053] The beam retarder 210 is connected to ...

Embodiment 2

[0064] On the basis of Embodiment 1, in this embodiment, as image 3 As shown, the reflector 220 of the beam shaper used for neutron capture therapy includes a first reflector inner surface 221, the first reflector inner surface 221 is a parabolic curved surface, and the target 120 is set on the first The reflector inner surface 221 is at the focal point of the parabolic curved surface. The neutron beams irradiated in various directions are reflected as neutron beams parallel to the axial direction. In this embodiment, the internal surface of the reflector is set as a parabolic curved surface, and the target 120 is arranged at the focal point of the parabolic curved surface. When the neutron beam emitted from the target 120 is emitted along the axial direction, the 130, when the neutron beam emitted from the target 120 deviates from the axial direction, the internal surface reflection of the reflector through the parabolic curved surface is adjusted to a direction parallel to...

Embodiment 3

[0066] The difference between this embodiment and Embodiment 1 is:

[0067] Such as Figure 5 As shown, in the beam shaper for neutron capture therapy, the gamma photon absorbing layer 321 and the thermal neutron absorbing layer 322 are non-adjacently arranged, wherein the gamma photon absorbing layer 321 is arranged at the beam exit 130, and the thermal neutron absorbing layer 322 A neutron absorbing layer 322 is disposed proximate to the beam moderator 210 .

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Abstract

The invention belongs to the field of neutron capture therapy, and discloses a beam shaping body for neutron capture therapy. The beam shaping body comprises a beam channel part, a beam shaping part and a beam shielding part; the beam channel part comprises a beam inlet, a target material and a beam outlet, the beam shaping part comprises a beam retardance body and a reflection body, and the beamshielding part comprises a radiation shielding body and an outlet shielding body. According to the beam shaping body, the outlet shielding body is arranged at the beam outlet so that useless or harmful rays emitted from the beam outlet during the therapy can be reduced to the greatest degree under the conduction that the influence on the mass of a neutron beam is as small as possible, and the damage caused by non-therapeutic rays to patients during the therapy is reduced; meanwhile, the inner surface of the reflection body is provided with a parabolic curved surface, the direction of the neutron beam can be controlled to make the neutron beam parallelly emitted from the beam outlet in a direction required by the therapy as much as possible, the intensity of the therapeutic beam at the beamoutlet can be improved, and the therapy effect and safety are improved.

Description

technical field [0001] The invention relates to the field of neutron capture therapy, in particular to a beam shaper for neutron capture therapy. Background technique [0002] Neutron capture therapy combines the characteristics of chemotherapy and radiation therapy. The concept of target therapy in chemotherapy is used in radiation therapy. As an effective means of treating cancer, its application has gradually increased in recent years. Among them, boron neutron capture therapy is the most common, which provides a better cancer treatment option than traditional radiation through the specific accumulation of boron-containing drugs in tumor cells and precise neutron beam adjustment. Since the ideal neutron source for boron neutron capture therapy is epithermal neutrons at the keV energy level, neutrons for boron neutron capture therapy can be supplied by nuclear reactors or accelerators. In order to generate a sufficient neutron flux, a higher energy proton is usually selec...

Claims

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Application Information

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IPC IPC(8): A61N5/10
CPCA61N5/1043A61N2005/109
Inventor 林洪涛陈朝斌李国威李建霖
Owner SUNSHINE LAKE PHARM CO LTD
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