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Application of gooseberry anthocyanins in the preparation of anti-hepatic fibrosis drugs or health products

An anti-hepatic fibrosis and anthocyanin technology, which is applied in the application field of medicine or health care products, can solve the problems of affecting endocrine function and digestive tract reaction, high cost, strong side effects, etc., and achieve a complete and clear liver tissue structure, even size effect

Active Publication Date: 2019-08-09
山东凯普菲特生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, chemically synthesized drugs have high cost, high toxicity, and strong side effects, which will affect side effects such as endocrine function and gastrointestinal reactions.

Method used

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  • Application of gooseberry anthocyanins in the preparation of anti-hepatic fibrosis drugs or health products
  • Application of gooseberry anthocyanins in the preparation of anti-hepatic fibrosis drugs or health products
  • Application of gooseberry anthocyanins in the preparation of anti-hepatic fibrosis drugs or health products

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Experimental program
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Effect test

Embodiment 1

[0018] (1) Preparation method

[0019] Preparation of gooseberry anthocyanin extract: Weigh 100g of gooseberry fruit, soak it with 60% ethanol at 60-70°C for 1h, put it into an ultrasonic cleaner for 30min, and do so twice in a row, and pass through the macroporous adsorption resin AB- 8 After purification, the extract was concentrated with a rotary evaporator, and vacuum freeze-dried to obtain gooseberry anthocyanin dry powder.

[0020] The main monomer components of gooseberry anthocyanins are cyanidin 3-O-glucoside and cyanidin 3-O-rutinoside , Delphinidin 3-O-glucoside (delphinidin 3-O-glucoside), delphinidin 3-O-rutinoside (delphinidin 3-O-rutinoside).

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PUM

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Abstract

The invention relates to application of gooseberry anthocyanin in preparation of anti-hepatic fibrosis drugs or health care products. The gooseberry anthocyanin is adopted as a raw material and used independently or combined with other drugs with an anti-hepatic fibrosis function to be prepared into any dosage forms of anti-hepatic fibrosis drugs or health care products suitable for being orally taken according to a preparation method of conventional preparations. The gooseberry anthocyanin has very strong capacity in preventing hepatic fibrosis.

Description

technical field [0001] The invention belongs to the field of health foods and medicines, and in particular relates to the application of gooseberry anthocyanins in the preparation of medicines or health products capable of preventing liver fibrosis. Background technique [0002] Hepatic fibrosis (fibrosis of liver) is a pathological change caused by chronic liver damage caused by various reasons. necessary stage. It is now believed that liver fibrosis may be reversed to normal, while liver cirrhosis is not. The current research focuses on the interaction between molecule and molecule, molecule and cell and cell and cell. Although there has been some progress in diagnosis and treatment, there is still a lack of definitive and effective drugs. [0003] Liver fibrosis health products can prevent liver fibrosis to a certain extent, promote health and reduce liver damage. At present, anti-hepatic fibrosis drugs can be divided into two categories: traditional Chinese medicine ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/352A61K36/185A61P1/16C07D311/62A23L33/105
CPCA23L33/105A23V2002/00A61K31/352A61K36/185A61P1/16C07D311/62A23V2200/30A23V2250/2104
Inventor 魏杰高军周志权杨静
Owner 山东凯普菲特生物科技有限公司
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