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A kind of chitosan oligosaccharide oral solution and preparation method thereof

A technology for oral chitosan oligosaccharide liquid and oral liquid is applied in the field of oral chitosan oligosaccharide solution and its preparation, which can solve the problems of strong hygroscopicity of chitosan oligosaccharide, unstable taste of preparations, etc. Simple preparation method

Active Publication Date: 2021-04-06
GUANGDONG PHARMA UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] The purpose of the present invention is to provide a kind of obviously improving chitosan liquid preparation stability, the oral liquid preparation of chitosan oligosaccharide that improves mouthfeel for strong hygroscopicity of chitosan oligosaccharide in the prior art, unstable preparation and poor mouthfeel technical problem Prescription process

Method used

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  • A kind of chitosan oligosaccharide oral solution and preparation method thereof
  • A kind of chitosan oligosaccharide oral solution and preparation method thereof
  • A kind of chitosan oligosaccharide oral solution and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] Embodiment 1 chitosan oligosaccharide oral solution

[0028] prescription:

[0029] Oligochitosan 25g ethyl maltol 2g Sodium carboxymethyl cellulose 1g Potassium sorbate 2g sodium benzoate 0 xanthan gum 0.5g polyvinylpyrrolidone 1g Sulfurous acid 0 gallic acid 0

[0030] Preparation method: Take an appropriate amount of purified water, add chitosan oligosaccharides, preservatives, and stabilizers according to the prescription amount, shake in a constant temperature air bath until the dissolution and inclusion are complete, then add flavoring agents, and finally adjust the pH to 7.3.

Embodiment 2

[0031] Embodiment 2 chitosan oligosaccharide oral solution

[0032] prescription:

[0033] Oligochitosan 30g ethyl maltol 2g Sodium carboxymethyl cellulose 0 Potassium sorbate 0 sodium benzoate 4g xanthan gum 2g polyvinylpyrrolidone 0 Sulfurous acid 0 gallic acid 0

[0034] Preparation method: Take an appropriate amount of purified water, add chitosan oligosaccharides, preservatives, and stabilizers according to the prescription amount, shake in a constant temperature air bath until the dissolution and inclusion are complete, then add flavoring agents, and finally adjust the pH to 7.3.

Embodiment 3

[0035] Embodiment 3 chitosan oligosaccharide oral solution

[0036] prescription:

[0037]

[0038]

[0039] Preparation method: Take an appropriate amount of purified water, add chitosan oligosaccharides, preservatives, and stabilizers according to the prescription amount, shake in a constant temperature air bath until the dissolution and inclusion are complete, then add flavoring agents, and finally adjust the pH to 7.3.

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PUM

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Abstract

The invention provides a chitosan oligosaccharide oral liquid and a preparation method thereof. The oligochitosan oral liquid comprises 25-40 parts of oligochitosan, 1-3 parts of flavoring agent, 2-4 parts of preservative and 1.5-2 parts of stabilizer. The chitosan oligosaccharide oral liquid of the invention obviously improves the stability of the chitosan oligosaccharide liquid preparation and improves the mouthfeel of the chitosan oligosaccharide. The chitosan oligosaccharide oral liquid of the invention has good stability, ideal taste and remarkable slimming effect.

Description

technical field [0001] The invention belongs to the technical field of pharmacy, in particular to a chitosan oligosaccharide oral solution and a preparation method thereof. Background technique [0002] Obesity, the most common metabolic imbalance, is becoming more common around the world, not only in Western societies, but also in developing countries as people become wealthier. Because obesity often induces hypertension, coronary heart disease, hyperlipidemia, fatty liver, cholecystitis, cholelithiasis, diabetes, impaired glucose tolerance, pulmonary insufficiency, obesity can also weaken the body's resistance and make the immune function Decline and abnormal blood rheology can lead to cerebral infarction, cerebral hemorrhage, myocardial infarction, respiratory diseases, osteoarthritis, varicose veins of lower extremities, women's amenorrhea, infertility, etc., thus becoming a public health problem of global concern. [0003] Since obesity can lead to serious health probl...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/722A61K31/702A61K9/08A61K47/38A61K47/22A61K47/36A61K47/32A61K47/04A61K47/12A61P3/04
CPCA61K9/0053A61K31/702A61K31/722A61K47/02A61K47/12A61K47/22A61K47/32A61K47/36A61K47/38A61P3/04
Inventor 苏政权
Owner GUANGDONG PHARMA UNIV
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