Tension stimulation device for inducing rat thoracolumbar spine yellow ligament ossification and application

A stimulating device and ligamentum flavum technology, which is applied in veterinary instruments, veterinary surgery, medical science, etc., can solve the problems of lack of model building methods, and achieve the effect of avoiding pollution of the platform and facilitating cleaning

Pending Publication Date: 2018-12-25
SECOND AFFILIATED HOSPITAL SECOND MILITARY MEDICAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there is no corresponding stimulation device in the prior art that can meet the above requirements, and there is even a lack of systematic model building methods.

Method used

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  • Tension stimulation device for inducing rat thoracolumbar spine yellow ligament ossification and application
  • Tension stimulation device for inducing rat thoracolumbar spine yellow ligament ossification and application
  • Tension stimulation device for inducing rat thoracolumbar spine yellow ligament ossification and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0043] figure 1 It is a schematic structural diagram of the tension stimulation device for inducing ossification of the thoracolumbar ligamentum flavum in rats in Example 1 of the present invention.

[0044] Such as figure 1 As shown, the tension stimulation device 100 for inducing ossification of the thoracolumbar ligamentum flavum in rats includes a bracket 1 , a fixed elastic platform 2 for rats, a tension stimulation component 3 , a power component 4 and a power conversion component 5 . The rat fixed elastic platform 2 is arranged on the top of the bracket 1 and has a certain elastic modulus; the tension stimulation component 3 is arranged under the rat fixed elastic platform 2, and stimulates the thoracolumbar spine of the rat on the rat fixed elastic platform 2 ; One side of the power conversion component 5 is connected to the tension stimulation component 3, and the other side is connected to the power component 4, and the power component 4 is arranged on the support p...

Embodiment 2

[0061] In the second embodiment, the same structures as those in the first embodiment are given the same symbols, and the same descriptions are omitted.

[0062] The only difference between the tension stimulation device for inducing ossification of the thoracolumbar ligamentum flavum in rats in Example 2 and the device in Example 1 is the difference in power conversion components, such as Figure 4 As shown, in the tension stimulation device 200 for inducing ossification of the thoracolumbar ligamentum flavum in rats, the power conversion component 6 is omitted, and the stimulating rod adjusting wheel 61 is directly installed on the motor, and the stimulating rod adjusting wheel is a bearing eccentric wheel. It can also be considered that in the device of this embodiment, the transmission member includes a bearing frame installed on the output shaft of the motor, and the stimulating rod adjustment wheel is an eccentric wheel installed on the bearing frame.

[0063] The eccent...

Embodiment 3

[0064] Embodiment three rat ligamentum flavum ossification model construction method

[0065] This example uses the tension stimulation device in Embodiment 1 or 2 to construct a rat model of ossification of the ligamentum flavum to verify the tension stimulation device of the present invention, and at the same time provides a method for constructing a model of ossification of the ligamentum flavum in rats. details as follows:

[0066] 1. Experimental materials and design:

[0067] 42 male SD rats, weighing 160-180g (174.7±3.6g), were reared at SPF level, provided with food and water, and turned on / off the lights for 12 hours. All rats were adapted to feeding for 7 days before modeling.

[0068] The experimental rats were randomly divided into two groups, the experimental group and the blank control group. A total of 24 rats in the experimental group (tension stimulation group) were induced with a tension stimulation generating device; a blank control group consisted of 18 r...

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PUM

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Abstract

The invention provides a tension stimulation device for inducing rat thoracolumbar spine yellow ligament ossification and application. The device comprises a support, a rat fixing elastic platform arranged at the top end of the support, a tension stimulation assembly arranged at the lower end of the rat fixing elastic platform, a power assembly and a power conversion assembly arranged between thetension stimulation assembly and the power assembly, wherein the tension stimulation assembly comprises a vertically-moving stimulation rod, an arch-shaped bracket arranged at the top end of the stimulation rod and used for stimulating the rat thoracolumbar spine, and a power conversion assembly connecting piece arranged at the bottom end of the stimulation rod; the power conversion assembly comprises a transmission piece connected with the power assembly, and a stimulation rod adjusting wheel installed on the transmission piece and matched with the power conversion assembly connecting piece.

Description

technical field [0001] The invention belongs to the technical field of building animal models of ligamentum flavum, and in particular relates to a tension stimulation device for inducing ossification of the thoracolumbar ligamentum flavum in rats and a method for constructing a model of ossification of the ligamentum flavum in rats using the device. Background technique [0002] Ossification of ligamentum flavum (OLF) is a heterotopic ossification of the ligamentum flavum of the spine, mostly in the lower thoracic spine, which can lead to spinal stenosis and neurological dysfunction. The onset of OLF is insidious and the development is slow. The clinical manifestations are mainly limb sensation, movement disturbance or defecation and sexual dysfunction caused by chronic compression of the spinal cord. treatment approach. [0003] OLF has a high incidence in Asia and more and more reports in China. It has become a common and frequently-occurring disease in orthopedics, but i...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61D1/00
CPCA61D1/00
Inventor 陈雄生赵寅周盛源苑博唐一钒任丽君
Owner SECOND AFFILIATED HOSPITAL SECOND MILITARY MEDICAL UNIV
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