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Traditional Chinese medicine compound composition with taxus chinensis as monarch drug and application of traditional Chinese medicine compound composition

A taxus and composition technology, applied in the field of traditional Chinese medicine compound compositions, can solve the problems of great killing of immune cells, poor quality of life of patients, high toxicity of chemotherapeutic drugs and the like

Active Publication Date: 2019-01-04
HEILONGJIANG UNIV OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, most of the drugs for clinical treatment of tumors are chemical drugs. Due to the high toxicity of chemotherapeutic drugs, they can greatly kill the body's own immune cells such as white blood cells and lymphocytes, and the quality of life of patients is poor.

Method used

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  • Traditional Chinese medicine compound composition with taxus chinensis as monarch drug and application of traditional Chinese medicine compound composition
  • Traditional Chinese medicine compound composition with taxus chinensis as monarch drug and application of traditional Chinese medicine compound composition
  • Traditional Chinese medicine compound composition with taxus chinensis as monarch drug and application of traditional Chinese medicine compound composition

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Experimental program
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Effect test

specific Embodiment approach 1

[0015] Specific embodiment one: In this embodiment, a kind of traditional Chinese medicine compound composition using yew as the monarch drug consists of 15-25g of yew, 10-20g of Ligustrum lucidum, 25-40g of Ganoderma lucidum, 25-30g of Scutellaria barbata and 15- 20g composition.

[0016] The beneficial effect of this implementation mode:

[0017] The traditional Chinese medicine compound composition with yew as the monarch drug in this embodiment has the effect of strengthening the body and strengthening the body, and can improve the immunity of the body. Through the separation of immune system components and the detection of spleen index, it can be seen that the spleen index of nude mice in the compound group is higher than The increase in the positive control group indicates that the Chinese medicine compound in this embodiment improves the immunity of nude mice.

[0018] This compound has the effects of promoting blood circulation, removing blood stasis and strengthening...

specific Embodiment approach 2

[0019] Specific embodiment two: the difference between this embodiment and specific embodiment one is: the Chinese medicine compound composition is composed of 18-22g of Chinese yew, 12-18g of Ligustrum lucidum, 28-35g of Ganoderma lucidum, 28-30g of Scutellaria barbata and Gongying 18 -20g composition. Others are the same as in the first embodiment.

specific Embodiment approach 3

[0020] Embodiment 3: The difference between this embodiment and Embodiment 1 or 2 is that the Chinese medicine compound composition is composed of 20g of Taxus chinensis, 15g of Ligustrum lucidum, 30g of Ganoderma lucidum, 30g of Scutellaria barbata and 20g of Herba Scutellariae. Others are the same as in the first or second embodiment.

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Abstract

The invention relates to a traditional Chinese medicine compound composition with taxus chinensis as a monarch drug and the application of the traditional Chinese medicine compound composition. The invention provides a traditional Chinese medicine compound composition with taxus chinensis as a monarch drug and the application of the traditional Chinese medicine compound composition. The traditional Chinese medicine compound composition with the taxus chinensis as the monarch drug comprises taxus chinensis, fructus ligustri lucidi, ganoderma lucidum, sculellaria barbata and dandelion. The traditional Chinese medicine compound composition provided by the invention is applied to the preparation of an anti-tumor drug. According to the invention, different concentrations of drug-containing serums show a good proliferation inhibition effect on tumor cells and have concentration dependence. In an in-vivo experiment, a traditional Chinese medicine compound of the traditional Chinese medicine compound composition provided by the invention shows a good growth inhibition effect on a tumor cell nude-mouse transplanted tumor model, and the tumor-inhibiting rate of the high-dose group of the traditional Chinese medicine compound is 50.8 percent. The traditional Chinese medicine compound composition provided by the invention is applied to the anti-tumor field.

Description

technical field [0001] The invention relates to a traditional Chinese medicine compound composition with yew as the main drug and its application. Background technique [0002] Malignant tumors have become a serious threat to human health today. Liver cancer is a common malignant tumor, ranking second in the global cancer death cause. The annual death rate of liver cancer patients in my country accounts for about 45% of the global liver cancer mortality rate, ranking first in the world, so the prevention and treatment of liver cancer has always been a hot spot in medical research. At present, most of the drugs for clinical treatment of tumors are chemical drugs. Due to the high toxicity of chemotherapeutic drugs, they can greatly kill the body's own immune cells such as white blood cells and lymphocytes, and the quality of life of patients is poor. Traditional Chinese medicine can improve the symptoms of patients with advanced liver cancer, improve immunity and quality of ...

Claims

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Application Information

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IPC IPC(8): A61K36/638A61K36/13A61P1/16A61P35/00A61P37/04
CPCA61K36/074A61K36/13A61K36/288A61K36/539A61K36/638A61P1/16A61P35/00A61P37/04A61K2300/00
Inventor 孙阳常佳怡韩海伟陶雪莲姜德友
Owner HEILONGJIANG UNIV OF CHINESE MEDICINE
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