Influenza virus immunogenicity composition and application thereof

An immunogenic, influenza virus technology, applied in the direction of antiviral agents, organic active ingredients, medical preparations containing active ingredients, etc. Simple, improve efficiency, solve the effect of virus lag

Inactive Publication Date: 2019-03-22
李伟
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, the drugs for preventing influenza virus, due to the continuous upgrading of the virus, often lead to a lag in the prevention effect. It is necessary to continuously develop new drugs for prevention, which consumes a lot of research, and the prevention effect is poor. In view of the above, we propose an influenza virus immunogen Sexual composition and its application

Method used

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Embodiment Construction

[0019] The technical solutions in the embodiments of the present invention will be clearly and completely described below in conjunction with the embodiments of the present invention. Apparently, the described embodiments are only some, not all, embodiments of the present invention. Based on the embodiments of the present invention, all other embodiments obtained by persons of ordinary skill in the art without making creative efforts belong to the protection scope of the present invention.

[0020] The invention provides a technical solution: an influenza virus immunogenic composition and its application, comprising the following components in weight percentage: 3-8% of ribonucleic acid, 0.3-1% of deoxyribonucleic acid, 0.7-1% of oligonucleotide 1.5%, polynucleotide 0.9-3.2%, five-carbon sugar 0.6-2.3%, fusion protein 1.2-1.5%, thymine 1-4%, cytosine 1.2-4.3%, antiviral polypeptide 0.8-1.5%, Cytokine mimetic peptide 1.1-3.7%, small molecule active peptide 0.4-2.8%, type 8 caps...

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Abstract

The invention discloses an influenza virus immunogenicity composition and application thereof. The composition comprises the following components in percentage by weight: 3-8% of ribonucleic acid, 0.3-1% of desoxyribonucleic acid, 0.7-1.5% of oligonucleotides, 0.9-3.2% of polynucleotide, 0.6-2.3% of pentose, 1.2-1.5% of fusion protein, 1-4% of thymine, 1.2-4.3% of cytosine, 0.8-1.5% of antiviral polypeptide, 1.1-3.7% of cell factor simulation peptide, 0.4-2.8% of small molecular active polypeptide, 0.6-1.5% of 8-type capsular polysaccharide, 0.2-0.5% of Pn-serum type 12F, 1.2-1.8% of lactic acid, 0.2-0.4% of glycollic acid, 0.15-0.3% of polysorbate, 0.1-0.2% of sorbitan trioleate and the balance of a polysaccharide solution. The composition disclosed by the invention is capable of efficiently preventing influenza viruses and greatly improving prevention efficiency, and is simple in processing method and worthy of popularization; the problem of hysteresis quality of a conventional drugfor viruses is solved, and the viruses cannot resist and upgrade after the composition is used.

Description

technical field [0001] The invention relates to the technical field of pharmaceutical compositions, in particular to an influenza virus immunogenic composition and its application. Background technique [0002] Influenza (abbreviated as influenza) is an acute respiratory infection caused by influenza virus, and it is also a disease with strong contagion and fast transmission speed. It is mainly spread through droplets in the air, person-to-person contact or contact with contaminated items. Typical clinical symptoms are: sudden onset of high fever, general pain, significant fatigue and mild respiratory symptoms. Generally, autumn and winter are the high-incidence period, and the complications and death caused by it are very serious. The disease is caused by influenza virus, which can be divided into three types: A (A), B (B), and C (C). Type A virus often undergoes antigenic variation, is highly contagious, spreads rapidly, and is very prone to large-scale epidemics. Type ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K38/02A61P31/16A61K31/513A61K31/7004A61K31/7084A61K31/7088A61K31/7105A61K31/711A61K31/715
CPCA61K38/02A61K31/513A61K31/7004A61K31/7084A61K31/7088A61K31/7105A61K31/711A61K31/715A61P31/16A61K2300/00
Inventor 李伟赵桂兰
Owner 李伟
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