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Composition with immunity enhancement effect and application of composition in preparation of immunoenhancement drugs and health food

A technology for enhancing immunity and immune enhancement, applied in the preparation of immune-enhancing drugs and health food, in the field of compositions for enhancing immunity, which can solve the problems of compositions for enhancing immunity, unclear specific ingredients of immune efficacy, etc. , to achieve the effects of increasing spleen index and thymus index, significant immune enhancement activity, and good potential for development and application

Inactive Publication Date: 2019-03-29
XINJIANG AILEXIN PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] However, the existing research is not clear about the specific components that exert the immune-enhancing effect, and there is no composition with clear components that can enhance immunity

Method used

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  • Composition with immunity enhancement effect and application of composition in preparation of immunoenhancement drugs and health food
  • Composition with immunity enhancement effect and application of composition in preparation of immunoenhancement drugs and health food
  • Composition with immunity enhancement effect and application of composition in preparation of immunoenhancement drugs and health food

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preparation example Construction

[0021] The preparation method of the composition in the present invention is to mix the above-mentioned allicin, alliin and garlic polysaccharide in proportion. In the present invention, after the garlic lectin, alliin and garlic polysaccharide are mixed according to the above ratio, the three can exert a synergistic effect, so that the composition can significantly improve the body's immunity.

[0022] The invention also provides the application of the composition in the preparation of immune enhancing medicine. In the present invention, the immune-enhancing drug is preferably an oral preparation, and the specific dosage form of the oral preparation is not particularly limited in the present invention, and a conventional oral preparation in the art can be used. In the present invention, the performance of the immune enhancement includes the improvement of the spleen index and the thymus index, the improvement of the total number of leukocytes, the improvement of the clearance...

Embodiment 1

[0026] A composition for enhancing immunity, comprising allicin, alliin and garlic polysaccharide in a mass ratio of 0.5:1.0:20. The composition is obtained by physically mixing the garlic lectin, alliin and garlic polysaccharide.

Embodiment 2

[0028] A composition for enhancing immunity, comprising allicin, alliin and garlic polysaccharide in a mass ratio of 0.6:0.9:22. The composition is obtained by physically mixing the garlic lectin, alliin and garlic polysaccharide.

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Abstract

The invention provides a composition with an immunity enhancement effect and belongs to the technical field of immunoregulation drugs. The composition comprises garlic lectin, alliin and garlic polysaccharide in a mass ratio being (0.4-0.6):(0.8-1.2):(17-25). The composition can increase a spleen index and a thymus index of immunosuppression mice, increase total white blood cells, a clearance index K and a phagocytic index alpha and ensure content levels of IL-2, TNF-alpha and IFN-gamma in serum to approach to normal levels and has the significant immunity enhancement effect.

Description

technical field [0001] The invention belongs to the technical field of immunomodulatory drugs, and in particular relates to a composition for enhancing immunity and its application in preparing immune enhancing drugs and health food. Background technique [0002] Garlic (Allium sativum L.) is the bulb of Allium genus garlic. It has a long history. It is the oldest medicinal plant planted by humans. It is also a medicinal and edible plant. It contains amino acids, sugars, glycosides and Sulfur-containing compounds and other chemical components vary with the variety, planting environment, harvesting and storage time. The diversity of garlic’s chemical components is the basis of garlic’s disease prevention and treatment. It has various pharmacological effects such as anti-oxidation, anti-tumor, anti-pathogenic microorganisms, anti-myocardial ischemia, lowering blood fat, and immune regulation. It is mainly used for anti-inflammatory, anti- Cancer, cardiovascular and cerebrovas...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/198A61K31/10A61K31/733A61P37/00A23L33/125A23L33/10
CPCA61K31/198A23L33/10A23L33/125A23V2002/00A61K31/10A61K31/733A61P37/00A61K2300/00A23V2200/324A23V2200/30
Inventor 李新霞许良宋百灵张海峰李瑞瑞肖文浚
Owner XINJIANG AILEXIN PHARMA
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