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Pharmaceutical composition for ears, preparation method and pharmaceutical preparation for ears

A composition and drug technology, applied in the field of ear pharmaceutical composition and ear pharmaceutical preparations, can solve the problems of discomfort, stickiness, thickness, etc.

Pending Publication Date: 2019-08-30
杭州医合科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the glycerin in this formula has a high boiling point, about 290°C, is not volatile, and is viscous and has poor fluidity. When the isopropanol in the formula volatilizes, the glycerin stays concentrated in the ear canal for a long time, and it will be sticky and thick. and a feeling of residue, causing discomfort

Method used

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  • Pharmaceutical composition for ears, preparation method and pharmaceutical preparation for ears
  • Pharmaceutical composition for ears, preparation method and pharmaceutical preparation for ears

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] Raw materials include: 98.50% isopropanol, 0.50% hydroxyethylurea, 0.50% boric acid, 0.50% allantoin.

[0022] The preparation method of the described ear medicine composition comprises:

[0023] Blend 10% isopropanol with hydroxyethylurea, boric acid and allantoin, and stir to obtain a mixed solution;

[0024] Then blend the remaining amount of isopropanol with the above mixed solution and stir to obtain the otic composition.

Embodiment 2

[0026] Raw materials include: 98.00% isopropanol, 1.00% hydroxyethylurea, 0.50% boric acid, 0.50% allantoin.

[0027] The preparation method of the described ear medicine composition comprises:

[0028] Blend 10% isopropanol with hydroxyethylurea, boric acid and allantoin, and stir to obtain a mixed solution;

[0029] Then blend the remaining amount of isopropanol with the above mixed solution and stir to obtain the otic composition.

Embodiment 3

[0031] Raw materials include: 99.00% isopropanol, 0.50% hydroxyethylurea, 0.40% boric acid, 0.10% allantoin.

[0032] The preparation method of the described ear medicine composition comprises:

[0033] Blend 10% isopropanol with hydroxyethylurea, boric acid and allantoin, and stir to obtain a mixed solution;

[0034] Then blend the remaining amount of isopropanol with the above mixed solution and stir to obtain the otic composition.

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Abstract

The invention relates to a pharmaceutical composition for ears. The pharmaceutical composition for ears comprises: 98.00-99.00% of isopropanol, 0.10-0.50% of hydroxyethyl urea, 0.10-0.50% of boric acid, 0.10-0.50% of allantoin and 0.10-0.50% of chitosan. The pharmaceutical composition for ears can rapidly volatilize water in the ear canal, has bacteriostatic effect, reduces the occurrence of diseases such as ear pain, otitis externa and otitis media, and can keep skin in the ear canal moist.

Description

technical field [0001] The invention relates to the technical field of ear medicines, in particular to an ear medicine composition, a preparation method and an ear medicine preparation. Background technique [0002] During daily activities such as swimming, bathing, and shampooing, it is inevitable that water will enter the ear canal. If the water in the ear canal is not cleaned up in time, it may cause tinnitus, hearing loss, earache, otitis externa, otitis media and other related diseases. At present, there is no related product in China. Several methods that people currently use to remove moisture in the ear canal include: hopping with one foot on the side of the ear, digging the ear with fingers, and absorbing water with a cotton swab. People's first reaction after getting water in their ears is to dig their ears with their fingers, but this method has no real effect on removing the water in the ear canal. In addition, many people choose to jump with their heads sidewa...

Claims

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Application Information

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IPC IPC(8): A61K33/22A61P27/16A61K31/045A61K31/17A61K31/4166
CPCA61K9/0046A61K31/045A61K31/17A61K31/4166A61K33/22A61P27/16A61K2300/00
Inventor 纪智煌章新天柳金兴吴科路
Owner 杭州医合科技有限公司
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