A kind of traditional Chinese medicine compound hydrogel for treating skin wound healing and its preparation method and application

Abstract

The invention discloses a Chinese medicine compound hydrogel for treating skin wound healing, which is composed of a Chinese medicine composition and a matrix, and is characterized in that the Chinese medicine composition comprises the following components in parts by weight: 25 to 35 parts of fried scutellaria baicalensis , 25-35 parts of Codonopsis, 15-25 parts of Angelica, 25-35 parts of fried Atractylodes macrocephala, 25-35 parts of white peony, 25-35 parts of Poria cocos, 6-15 parts of tangerine peel, 10-20 parts of frankincense, 10 parts of myrrh ~20 parts, 15~25 parts of Bletilla striata, 15~25 parts of Silver Flower, 15~25 parts of Coptis chinensis, 6~15 parts of raw licorice. Compared with the existing technology, it can promote the healing of skin wounds, improve the histopathology of damaged skin in rats, promote the chemotaxis of fibroblasts, and inhibit inflammation-related transcription factors; at the same time, it uses multiple components to play a synergistic effect, and has the effect of clearing away heat, detoxification and dryness. Dampness and tonifying qi and blood, nourishing yin, removing blood stasis and promoting muscle growth are used together, and the effect is more.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine, and in particular relates to a traditional Chinese medicine compound hydrogel for treating skin wound healing, a preparation method and application thereof. Background technique [0002] The skin is the body's first barrier to defend against external stimuli and damage. Skin damage caused by mechanical trauma will lead to microbial invasion, water and protein loss, endocrine and immune dysfunction, etc., and severe cases can cause death. Treatment of skin trauma Essential to human life and health. At present, we commonly use drugs such as antibiotics, anti-inflammatory drugs, sterols, and fibroblast growth-promoting drugs to treat skin wounds. However, the use of western medicines is easy to cause irritation and allergies to human skin, with many adverse reactions and expensive . Most traditional Chinese medicines are natural ingredients, which have the characteristics of fast wound ...

AI Technical Summary

Problems solved by technology

Of course, there are also Chinese medicine hydrogel formulations used for skin wound healing, but there are few reports. After reviewing the literature, it is found that the ingredients used in the reported Chinese medicine hydrogels are all single Chinese medicine ingredients, and the main function is muscle growth. Therefore, It is necessary to develop a compound hydrogel of multi-component traditional Chinese medicine ingredients to exert better curative effect

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