Composition and functional food for preventing myopia

Abstract

The invention is to provide an ophthalmic composition that is efficacious for preventing or treating myopia or ophthalmic diseases. In particular, to provide: an ophthalmic composition that is efficacious for growing children and young adults, in whom myopia is likely to occur or develop, as well as middle-aged and senior adults who are liable to be attacked by age-related ophthalmic diseases suchas cataract, glaucoma, retinal detachment, retinopathy, maculopathy, choroidal neovascular, posterior staphyloma and optic neuropathy; a functional food comprising the ophthalmic composition; and a screening method usable for searching for the same. The solutions is that the ophthalmic composition or a functional food comprises at least one ingredient selected from the group consisting of crocetin and pharmaceutically acceptable salts thereof and ginkgo leaf extract.

Description

technical field [0001] The invention relates to a composition and functional food for preventing or treating myopia or eye diseases. More specifically, the present invention relates to a composition effective for age groups prone to myopia or worsening of myopia, especially children or young people in the growth period, and also effective for middle-aged and elderly people with increased risk of eye diseases Composition, and functional food comprising the composition. Background technique [0002] There are racial differences in the frequency of myopia. In particular, there are many Asians. Among them, Japanese people are prone to myopia, and the proportion of high myopia above -5D is also high. In addition, in recent years, myopia has gradually increased globally, and in Japan, the proportion of children with uncorrected visual acuity of less than 1.0 is also increasing year by year. In addition, it is known that myopia rapidly worsens in school children aged 7 to 12 (se...

AI Technical Summary

Problems solved by technology

However, although EGR-1 knockout mice can be seen to elongate the eye axis and worsen myopia, but for EGR-1, which is only one of the multiple myopia-related genes, it has not been determined that it can enhance its expression in vitro. Does the agent actually suppress myopia progression by inhibiting ocular axial elongation in vivo

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