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Gum-based chewing tobacco containing Ophiopogon japonicus extract and preparation method thereof

A technology of Ophiopogon japonicus extract and gum-based type, applied in the field of gum-based chewing tobacco containing Ophiopogon japonicus extract and its preparation, can solve the problems of no basic research reports, reduce oral risk, and improve oral epithelial cell death , the effect of reducing the risk of oral health

Active Publication Date: 2022-04-01
CHINA TOBACCO YUNNAN IND
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, Ophiopogon japonicus has no application in resisting cell death caused by osmotic stress, and there is no basic research report

Method used

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  • Gum-based chewing tobacco containing Ophiopogon japonicus extract and preparation method thereof
  • Gum-based chewing tobacco containing Ophiopogon japonicus extract and preparation method thereof
  • Gum-based chewing tobacco containing Ophiopogon japonicus extract and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036] A preparation method of gum-based chewing tobacco containing Ophiopogon japonicus extract, comprising the steps of:

[0037] Step (1), take Ophiopogon japonicus and crush it, grind it with ultrapure water until there are no particles larger than 2mm in diameter visible to the naked eye, shake and extract it several times, combine the extracts, centrifuge at 4°C, take the supernatant, supernatant Freeze-dried and stored for later use to obtain the Ophiopogon japonicus extract;

[0038] Step (2), in parts by weight, bake 10 parts of gum base at 40°C for 8 hours, add 20 parts of sweetener, 1 part of acid-base regulator, 1 part of flavoring agent, 0.1 1 part of food coloring, 1~5 parts of humectant, 1 part of tobacco powder crushed to >200 mesh, and 50 mg / g of gum-based Ophiopogon japonicus extract; mixed at 58°C until uniform, then extruded and rolled Pressing, cutting, aging, and packaging are finished products.

Embodiment 2

[0040] A preparation method of gum-based chewing tobacco containing Ophiopogon japonicus extract, comprising the steps of:

[0041] Step (1), take Ophiopogon japonicus and crush it, grind it with ultrapure water until there are no particles larger than 2mm in diameter visible to the naked eye, shake and extract it several times, combine the extracts, centrifuge at 4°C, take the supernatant, supernatant Freeze-dried and stored for later use to obtain the Ophiopogon japonicus extract;

[0042] Step (2), in parts by weight, bake 10 parts of gum base at 40°C for 8 hours, add 20 parts of sweetener, 1 part of acid-base regulator, 1 part of flavoring agent, 0.1 1 part of food coloring, 1 part of humectant, 1 part of tobacco powder crushed to >200 mesh, and 5 mg / g of gum-based Ophiopogon japonicus extract; mixed at 58°C until uniform, then extruded, rolled, Cutting, aging, and packaging are finished products.

[0043] In step (1), the number of extractions is 3 times, each time the ...

Embodiment 3

[0051] A preparation method of gum-based chewing tobacco containing Ophiopogon japonicus extract, comprising the steps of:

[0052] Step (1), take Ophiopogon japonicus and crush it, grind it with ultrapure water until there are no particles larger than 2mm in diameter visible to the naked eye, shake and extract it several times, combine the extracts, centrifuge at 4°C, take the supernatant, supernatant Freeze-dried and stored for later use to obtain the Ophiopogon japonicus extract;

[0053] Step (2), in parts by weight, bake 30 parts of gum base at 60°C for 12 hours, add 60 parts of sweetener, 5 parts of acid-base regulator, 5 parts of flavoring agent, 5 parts of 10 parts of food coloring, 5 parts of humectant and 10 parts of tobacco powder crushed to >200 mesh, and 50 mg / g gum-based Ophiopogon japonicus extract; mixed at 62 °C until uniform, then extruded, rolled, Cutting, aging, and packaging are finished products.

[0054] In step (1), the number of extractions is 3 time...

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Abstract

The invention relates to gum-based chewing tobacco containing Ophiopogon japonicus extract and a preparation method thereof, belonging to the technical field of smokeless tobacco products. Take Ophiopogon japonicus and crush it, extract it several times with ultrapure water, combine the extracts, centrifuge at 4°C, take the supernatant and freeze-dry to obtain the extract of Ophiopogon japonicus; bake the gum base at 40-60°C, Baking for 8~12 hours, adding sweetener, acid-base regulator, flavoring agent, food coloring, humectant and tobacco powder, mixing until uniform at 60°C, then extruding, rolling and cutting , Aging, sub-packaging is the finished product. The present invention finds that when people smoke gum-based chewing tobacco for a long time, the osmotic pressure of the microenvironment of oral epithelial cells increases, and the exposure of oral cells to a hyperosmotic environment will lead to cell death, and the product prepared by the present invention can greatly improve the existing The gum-based chewing tobacco can significantly reduce the oral health risk caused by smoking gum-based chewing tobacco due to the hypertonic environment that leads to the death of oral epithelial cells.

Description

technical field [0001] The invention belongs to the technical field of smokeless tobacco products, in particular to a gum-based chewing tobacco containing Ophiopogon japonicus extract and a preparation method thereof. Background technique [0002] Smokeless tobacco (Smokeless Tobacco, referred to as ST) products refer to tobacco products that are directly smoked through the mouth or nose without burning. Compared with traditional cigarettes, they have fewer harmful components and are less harmful; at the same time, they do not produce second-hand smoke. , can ease the contradiction between smoking ban and smoking in public places to a certain extent, and satisfy the physiological needs of smokers to a certain extent. Gum-based chewing tobacco, also known as new chewing tobacco, gum-based smokeless tobacco, tobacco chewing gum, gum-based tobacco, is a kind of tobacco and / or tobacco extract as the effective component, with edible gum base as the carrier , a novel tobacco prod...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A24B13/00A24B3/14A61K36/8968A61P1/02
CPCA24B13/00A24B3/14A61K36/8968A61P1/02
Inventor 杨继张慧杰高茜米其利刘春波段沅杏申钦鹏赵杨杨柳刘志华缪明明向阳
Owner CHINA TOBACCO YUNNAN IND
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