An interventional catheter, its preparation method and application
A technology of interventional catheters and catheters, which is applied in the field of medical equipment, can solve the problems of cation grafting density and strength to be improved, and achieve the effects of reducing adherent platelets, good hydrophilicity, and inhibiting the activation of platelets
Active Publication Date: 2022-05-31
上海威高医疗技术发展有限公司 +1
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Problems solved by technology
However, the density and strength of cationic grafting still need to be improved.
Method used
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preparation example Construction
[0039]
Embodiment 1
[0077] 1.5 The modified catheter is washed with ethanol and deionized water, and dried.
Embodiment 2
[0093] 2.5 The modified catheter is washed with ethanol and deionized water, respectively, and dried.
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The invention provides a preparation method of an interventional catheter, comprising: soaking a polyurethane catheter body in an aminopolyethylene glycol dopamine solution to obtain a polyurethane catheter grafted with aminopolyethylene glycol dopamine; The solution of the solution, the diamine compound solution and the alkylating agent are circulated in sequence in the polyurethane catheter of grafted aminopolyethylene glycol dopamine to flow; the carbodiimide compound and the N-N-hydroxysuccinimide The mixed solution and the hyaluronic acid solution circulate sequentially on the outer surface of the polyurethane catheter grafted with aminopolyethylene glycol dopamine; an interventional catheter is obtained. Compared with the prior art, on the one hand, the present invention forms a bottom anticoagulant surface antibacterial dual-functional coating on the inner surface of the catheter; on the other hand, grafts and fixes hyaluronic acid on the outer surface of the catheter to further improve the hydrophilicity of the polyurethane material , improve the maneuverability of the catheter during use, and at the same time prevent the intravascular tissue from adhering to the surface of the catheter.
Description
An interventional catheter, its preparation method and application technical field [0001] The present invention belongs to the technical field of medical equipment, in particular to a kind of interventional catheter, its preparation method and application. Background technique [0002] Interventional therapy is a minimally invasive treatment that utilizes high-tech means. Through the guidance of medical imaging equipment, the Precise instruments such as tubes and guide wires can be introduced into the human body, and the lesion can be accurately reached without opening the human tissue, and diagnosis and treatment can be carried out. New medical technology for treatment. Interventional therapy has the advantages of minimally invasive, high curative effect, quick effect, accurate positioning and strong repeatability. It has been widely used in clinical treatment. Interventional catheters are important for hemodialysis, intravenous nutrition infusion and hemodynamic moni...
Claims
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IPC IPC(8): A61M25/00A61L29/16A61L29/14A61L29/08A61L29/06
CPCA61M25/0045A61M25/0009A61L29/06A61L29/08A61L29/085A61L29/16A61L29/14A61L2300/404A61L2300/208A61L2300/42A61L2400/18A61L2420/02A61L2420/06A61L2420/08C08L75/04C08L71/02C08L5/08
Inventor 蔡冰李春明欧阳兆飞殷敬华栾世方吴刚
Owner 上海威高医疗技术发展有限公司