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FMRI data processing method for functional connection of language functional area of facial nerve paralysis

A technology for facial nerve paralysis and language function, applied in the field of medical image processing

Active Publication Date: 2020-08-25
CHINA JAPAN FRIENDSHIP HOSPITAL
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Problems solved by technology

Dysarthria is one of the common symptoms of FP, but there are few studies on the neural mechanism of language changes

Method used

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  • FMRI data processing method for functional connection of language functional area of facial nerve paralysis
  • FMRI data processing method for functional connection of language functional area of facial nerve paralysis
  • FMRI data processing method for functional connection of language functional area of facial nerve paralysis

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Embodiment Construction

[0019] Such as Image 6 As shown, the fMRI data processing method of the language functional area functional connectivity of this facial paralysis, it comprises the following steps:

[0020] (1) The fMRI data of several adult patients with peripheral facial paralysis and several healthy controls were collected with a magnetic resonance imager and a standard head orthogonal coil;

[0021] (2) Preprocessing the fMRI data in step (1) by using DPARSF software for auxiliary processing of resting state brain function data to remove abnormal data and noise;

[0022] (3) A total of 16 ROIs in the basal ganglia and language function areas were selected for functional connectivity FC analysis;

[0023] (4) Two-sample t-test was used to compare the difference in FC between the patient group and the control group, and the false discovery rate FDR method was used to correct for multiple comparisons, and the threshold was set to P image 3 );

[0024] (5) The Toronto facial nerve grading m...

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Abstract

According to the fMRI data processing method for functional connection of the language functional area of facial nerve paralysis, image data with high spatial resolution can be obtained while no injury is caused to a human body, and therefore the language functional area corresponding to facial nerve paralysis accompanied by dysmnesia can be accurately positioned. The method comprises the following steps: acquiring fMRI data of a plurality of adult peripheral facial paralysis patients and a plurality of health control persons by using a magnetic resonance imager and a standard head orthogonalcoil; adopting DPARSF software to preprocess the data, and removing abnormal data and noise; selecting 16 ROIs (Regions of Interest) of a base section area and a language functional area for functional connection FC analysis; comparing FC differences between the patient group and the control group by adopting a double-sample t test, carrying out multiple comparison and correction by adopting an FDR (False Discovery Rate) method, and setting a threshold value P to be less than 0.05; and evaluating the facial nerve function of all subjects by adopting a dolomb polyhedral nerve grading method TFGS, and analyzing and evaluating the correlation between the abnormal FC of the patient suffering from facial nerve paralysis and the oral muscle movement TFGS score.

Description

technical field [0001] The invention relates to the technical field of medical image processing, in particular to an fMRI data processing method for the functional connection of language functional areas of facial paralysis. Background technique [0002] Idiopathic peripheral facial paralysis (facial paralysis, FP) is a facial muscle dysfunction disease caused by facial nerve injury. Its clinical manifestations are mainly concentrated on the face, which can bring serious psychological impact to patients. Dysarthria is one of the common symptoms of FP, but there are few studies on the neural mechanism of language changes. Early identification of functional changes in brain language networks in patients with FP with dysarthria is of great significance for understanding the pathogenesis of the disease, providing early diagnosis and timely treatment. [0003] Language expression is achieved through a high degree of neuromuscular coordination of the vocal organs. The process o...

Claims

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Application Information

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IPC IPC(8): G06T7/00G06T5/00A61B5/055A61B5/00
CPCG06T7/0012A61B5/055A61B5/7203A61B5/725A61B5/0042G06T2207/10088G06T2207/30201A61B2576/026G06T5/70
Inventor 马国林高文文韩小伟
Owner CHINA JAPAN FRIENDSHIP HOSPITAL
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