Probiotics composition and application thereof and probiotics product

Abstract

The invention discloses a probiotics composition and application thereof and a probiotics product. The probiotics composition comprises in parts by weight: 20 to 40 parts of parabacteroides distasonis, 20 to 40 parts of christensenella minuta and 20 to 40 parts of akkermansia muciniphila. By the probiotics composition containing the parabacteroides distasonis, the christensenella minuta and the akkermansia muciniphila in a specific proportion, intestinal permeability can be effectively reduced and the intestinal inflammation level is reduced, so that an intestinal physical barrier, chemical barrier and immunologic barrier can be effectively improved, and intestinal barrier function abnormalities caused by diet / metabolic diseases is obviously improved or relieved; and the probiotics composition can be widely used for preparing drugs, foods or health care products for regulating intestinal barrier functions. Moreover, the probiotics composition also can improve a case of body weight, blood glucose level or blood lipid level abnormalities caused by the metabolic disease.

Description

technical field [0001] The invention relates to the technical field of microbial medicine, in particular to a probiotic composition, its application and a probiotic product. Background technique [0002] The intestinal tract is not only an organ for digestion and absorption, but also an organ that integrates endocrine, immune and barrier functions. Under normal physiological conditions, the intestinal tract can digest and absorb various nutrients, and at the same time control the intestinal microecology Balance, inhibit metabolites from entering the body, and secrete hormones to play the intestinal barrier function and keep the body in a healthy state. [0003] When the intestinal barrier is damaged, the intestinal permeability increases, and at this time, pathogenic microorganisms and endotoxins in the intestinal tract can enter the blood or tissues through the intestinal barrier system, thereby causing the body to be in a disease state. Therefore, maintaining normal intes...

AI Technical Summary

Problems solved by technology

Although a large number of studies have shown that probiotics can regulate the structure of intestinal flora, there is a lack of probiotic composition products that can effectively improve or enhance the intestinal physical barrier, chemical barrier and immune barrier function

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