Micro-droplet generating device

Abstract

The invention provides a micro-droplet generating device, which comprises a control module, a gas supply module, a chip moving module, an air pressure adjusting module and the like, wherein a gas cylinder is arranged in the gas supply module, a gas cavity is formed in the air pressure adjusting module, the gas cylinder is provided with a first pressure sensor for monitoring the gas pressure in thegas cylinder in real time, a second pressure sensor for monitoring the pressure of gas in the gas cavity in real time is arranged on the gas cavity, an oil-phase electromagnetic valve and a water-phase electromagnetic valve which are connected in parallel are arranged on the gas path output side of the gas cavity, and the control module is configured to control the gas release valve or the oil-phase electromagnetic valve and the water-phase electromagnetic valve to generate gas release action according to the pressure values monitored by the first pressure sensor and the second pressure sensor in real time and when the pressure values exceed a preset pressure threshold range. According to the micro-droplet generating device, secondary real-time monitoring and pressure stabilization regulation and control on the gas pressure in the gas path can be achieved, the gas pressure fluctuation is prevented from being too large, and then the stability of micro-droplet generation is guaranteed.

Description

technical field [0001] The invention belongs to the technical field of microfluidic chips, and in particular relates to a micro droplet generating device. Background technique [0002] Droplet-based microfluidics (droplet-based microfluidics) is a technology developed on microfluidic chips in recent years to manipulate tiny volumes of liquids. Micro-droplet technology is a micro-nano technology that uses the interaction between flow shear force and surface tension to divide continuous fluid into discrete nano-scale and below-volume droplets in micro-scale channels. [0003] So far, there are mainly two types of micro-droplets: gas-liquid phase droplets and liquid-liquid phase droplets. The application of gas-liquid droplets is limited due to their easy volatilization and cross-contamination in microchannels. Liquid-liquid phase droplets are divided into oil-in-water (O / W), water-in-oil (W / O), oil-in-water-in-oil (O / W / O) and water-in-water droplets according to the differen...

AI Technical Summary

Problems solved by technology

Most of the existing microfluidic chips use the control mode of the micro-injection pump. Due to the limited air pressure control accuracy of the existing micro-injection pump, the pass rate of the generated micro-droplets is relatively low. Therefore, only by controlling the micro-injection pump The generated micro-droplets can no longer meet the increasingly high-standard experimental requirements, and the present invention is proposed based on the aforementioned deficiencies of the prior art

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