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Application of vitamin C in preparation of drug for preventing cerebral malaria

A vitamin and brain-type technology, applied in drug delivery, drug combination, anti-infective drugs, etc., can solve problems such as cerebral malaria that have not been raised by research

Inactive Publication Date: 2020-12-11
TIANJIN MEDICAL UNIV +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There have been studies reporting attempts to use vitamin C in the treatment of malaria, but the highest dose is only 100mg / kg, and no research has proposed the use of vitamin C to prevent cerebral malaria

Method used

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  • Application of vitamin C in preparation of drug for preventing cerebral malaria
  • Application of vitamin C in preparation of drug for preventing cerebral malaria

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] The experimental method and result of the application of vitamin C in the preparation of the drug for preventing cerebral malaria are as follows:

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Abstract

The invention discloses an application of vitamin C in preparation of a drug for preventing cerebral malaria. The dosage of the vitamin C is 4 g / kg. The invention mainly investigates the effect of high-dosage vitamin C in prevention of cerebral malaria of malaria mice, and focuses on solving the problem of how to prevent serious malaria complication, namely cerebral malaria. The difficulty of theinvention is to find a drug for preventing cerebral malaria. The innovation point of the invention is to adjust the dosage and the using way of the known drug for preventing cerebral malaria.

Description

technical field [0001] The invention belongs to the technical field of medicine development, and in particular relates to the application of vitamin C in the preparation of medicines for preventing cerebral malaria. Background technique [0002] Malaria is an infectious parasitic disease caused by Plasmodium infection of the human body, mainly caused by the bite of female Anopheles mosquitoes infected by Plasmodium. According to the World Malaria Report 2019 released by the World Health Organization, there were 228 million malaria cases worldwide in 2018, of which 405,000 died from the disease. With the increase of international exchanges and foreign trade in recent years, the incidence of malaria infected abroad and reimported into my country is on the rise year by year. Clinical manifestations of malaria vary according to the course of the disease and can range from more common symptoms such as fever, chills, and headache to more severe symptoms including severe anemia, r...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/375A61P33/06A61P25/00
CPCA61K31/375A61K9/0019A61P33/06A61P25/00Y02A50/30
Inventor 王倩胡俊杰史小雨徐子豪刘影
Owner TIANJIN MEDICAL UNIV