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Compounds with synergistic effect on Shenzimycin and their compositions and applications

A styrazinomycin and composition technology, which is applied in the directions of chemicals, applications, biocides, etc. for biological control, can solve the problems of increasing the dosage of fungicides and environmental safety problems, and reduce the risk of drug resistance and environmental protection. good compatibility

Active Publication Date: 2022-02-15
HUNAN AGRICULTURAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, excessive use of this drug will easily cause the bacteria to develop resistance and drug resistance to a single agent, and thus fall into a vicious cycle in which the dose of fungicides is continuously increased due to resistance, drug resistance, etc., thereby aggravating environmental safety problems.

Method used

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  • Compounds with synergistic effect on Shenzimycin and their compositions and applications
  • Compounds with synergistic effect on Shenzimycin and their compositions and applications
  • Compounds with synergistic effect on Shenzimycin and their compositions and applications

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0047] Through the above test steps, the compound solutions of shenzimycin, jatrorrhizine and palmatine were prepared respectively, and their EC to different pathogenic bacteria were tested. 50 value, the result is as follows:

[0048]

[0049]

Embodiment 2

[0051] Through the above test steps, respectively configure the compound solution of Shenzimycin and Jatrorrhizine, and the composition solution of Shenzimycin and Jatrorrhizine in a mass ratio of 1:20, 1:10, 1:5, 1:2.5 , to test its EC against different pathogenic bacteria 50 Value and synergistic multiple, where the calculation of synergistic multiple is:

[0052] Synergistic multiple = (EC of each compound medicinal liquid 50 Value - Shenzimycin EC 50 value) / EC of each compound liquid 50 value.

[0053] The test results are as follows:

[0054] Effect on tea anthracnose:

[0055]

[0056] Effect on tea Fusarium:

[0057]

[0058] Effect on tea stem point mold:

[0059]

[0060]

Embodiment 3

[0062] Through the above test steps, respectively configure the compound solution of Shenzimycin and Palmatine, and the composition solution of Shenzimycin and Palmatine in a mass ratio of 1:20, 1:10, 1:5, 1:2.5 , to test its EC against different pathogenic bacteria 50 value and multiplier.

[0063] The test results are as follows:

[0064] Effect on tea anthracnose:

[0065]

[0066] Effect on tea Fusarium:

[0067]

[0068] Effect on tea stem point mold:

[0069]

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Abstract

The present invention discloses a compound with synergistic effect on Shenzimycin and its composition and application, wherein the compound is selected from one or more of proberberine-type alkaloids, derivatives thereof, or pharmaceutically acceptable salts thereof kind. The compound of the present invention can produce a significant synergistic effect on the inhibition of tea tree fungus at a low dose of shenazamycin.

Description

technical field [0001] The invention relates to the technical field of fungal disease control. Background technique [0002] Fungal diseases of tea trees are a kind of diseases that can obviously harm the growth of tea trees or the quality of tea leaves. Among them, the most common tea tree fungi include Colletotrichum sp., Fusarium sp. and Phomasp., etc., which are easy to occur in large areas in alpine tea gardens, and often harm tea tree buds, leaves, stems and roots, causing extreme damage. large economic loss. [0003] At present, the prevention and treatment of fungal diseases of tea is still dominated by chemical control, such as the fungicide shenzimycin, which is a compound fungicide that is preferred in tea production. Shenzimycin is a kind of biological source pesticide with high efficiency, low toxicity and good environmental compatibility. However, excessive use of this drug will easily cause the bacteria to develop resistance and drug resistance to a single ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A01N43/60A01N43/90A01P3/00
CPCA01N43/60A01N43/90
Inventor 李冠华周鑫钰丁文兵
Owner HUNAN AGRICULTURAL UNIV
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