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A pathological slice device based on tumor molecular mechanism research experiment

A molecular mechanism and pathological slicing technology, applied in the field of medical devices, can solve the problems of slice damage, ineffective slicing operation, inconvenient blade cleaning, etc., to improve quality, facilitate continuous slice processing, and avoid contamination.

Active Publication Date: 2022-07-12
ANHUI MEDICAL COLLEGE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] In the process of tumor pathology research, it is often necessary to make pathological sections. The pathological section production process usually includes the following steps: First, take a certain size of lesion tissue, then embed the lesion tissue in paraffin block, cut it into thin slices with a microtome, and then Stain with hematoxylin-eosin (H-E), and further examine the lesion with a microscope. The existing technology uses a microtome to slice the embedded wax block of the pathological tissue, and there are problems such as inconvenient cleaning of the blade and inconvenient feeding and transportation of the sample during the slicing process. , the sectioning operation cannot be performed effectively, resulting in the cut-out section being destroyed by the residual substance of the knife. For this reason, a pathological sectioning device based on the research experiment of tumor molecular mechanism is needed

Method used

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  • A pathological slice device based on tumor molecular mechanism research experiment
  • A pathological slice device based on tumor molecular mechanism research experiment
  • A pathological slice device based on tumor molecular mechanism research experiment

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] The side of the cleaning rollers 48 that are close to each other is provided with a storage groove 61 arranged along its length direction, and a ring-shaped sealing plate 62 is installed at the opening of the storage groove 61. The outer convex surface of the plate 62 is installed with a cleaning cloth belt 63, one side of the cleaning roller 48 is installed with a feeding roller movably sleeved with the cleaning installation plate 47, and the other side of the cleaning roller 48 is installed with a movable sleeve with the cleaning installation plate 47. A drive motor is installed at one end of the feeding roller and the feeding roller protruding from the cleaning installation plate 47, the cleaning cloth belt 63 is wound around the feeding roller and the feeding roller, and one end of the storage tank 61 is installed with cleaning and cleaning. Roller 48 secures the socketed liquid inlet pipe.

Embodiment 2

[0036] The lift unit 10 includes a driven plate 12 that is slidably connected to the inner side wall of the housing 91 and moves in the horizontal direction. The bottom of one end of the driven plate 12 away from the pushing unit 99 is installed with a placement plate 11 arranged in the horizontal direction. The driven plate 12 One side of the first gear rack is installed along its length direction, one side of the first gear rack is engaged with a first gear that is movably sleeved with the cover 91, and one side of the first gear is engaged with the cover 91. The sleeved second gear is engaged with a second rack fixed to the outer side wall of the push-pull plate 71 , and a discharge channel 13 runs through the lower side of the cover 91 close to the partition plate 2 .

Embodiment 3

[0038] The sample conveying mechanism 7 includes an extension plate fixedly connected to the bottom of the support plate 5, and the extension plate extends from the discharge channel 6 to the inside of the box 1, and the bottom of the extension plate is installed with a chain one of a ring structure, and the inner ring of the chain one is installed. A sprocket is connected, the inner ring of the chain 1 is fixedly sleeved with a rotating rod that is movably sleeved with the extension plate, the bottom of the rotating rod is installed with a motor 2 that is fixed to the inner side wall of the box 1, and the outer ring of the chain 1 is fixedly connected. There is a connecting plate arranged along its length direction, and the top of the connecting plate is fixed with a holding box with an opening on the top.

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Abstract

The invention belongs to the technical field of medical devices, in particular to a pathological slicing device based on a tumor molecular mechanism research experiment. The following scheme is now proposed, including a box body. The partition plate runs through a tool channel, one end of the tool channel is installed with a cutting and cleaning mechanism, and the other end of the tool channel is installed with a support plate fixed to the inner side wall of the box and arranged in the horizontal direction. A feeding conveying mechanism is installed on the top of the . The invention realizes the conveying operation of the sample, and can use the intermittent clamping method to feed the material during cutting, which is convenient for the continuous slicing processing of the sample, and at the same time, the cutting knife can be cleaned during cutting, so as to avoid the residual cutting knife during cutting. The substance damages the slices, improves the quality of the slices, and prevents the cutter from contaminating the slices when cutting.

Description

technical field [0001] The invention relates to the technical field of medical devices, in particular to a pathological slice device based on a tumor molecular mechanism research experiment. Background technique [0002] In the process of tumor pathological research, it is often necessary to make pathological sections. The production process of pathological sections usually includes the following steps: first, take a certain size of diseased tissue, then embed the diseased tissue in a paraffin block, cut into thin slices with a microtome, and then Hematoxylin-eosin (H-E) staining is used to further examine the lesions with a microscope. In the prior art, the embedded wax block of the pathological tissue is sliced ​​by a microtome, which has the problems of inconvenient cleaning of the blade and inconvenient sample feeding and transportation during the slicing process. , the slicing operation cannot be performed effectively, resulting in the cut slices being destroyed by the ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): B26D1/10B26D7/08B26D7/02B26D7/06B26D7/32G01N1/28
CPCB26D1/10B26D7/088B26D7/02B26D7/0625B26D7/32G01N1/286G01N2001/2873
Inventor 鲍敏潘献柱
Owner ANHUI MEDICAL COLLEGE
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