Acquisition method and system for blood perfusion of hypothalamus and pituitary

Abstract

The invention relates to an acquisition method and system for blood perfusion of the hypothalamus and the pituitary. The method comprises the following steps: constructing a three-dimensional space model of the hypothalamus and the pituitary; collecting a blood perfusion magnetic resonance image of an individual brain, and acquiring a blood perfusion image of the individual brain, wherein the blood perfusion image comprises a cerebral blood flow parameter, a time parameter and a cerebral blood volume parameter; importing the blood flow perfusion image into the three-dimensional space model; and according to the blood perfusion model of the hypothalamus and the pituitary, acquiring perfusion parameters corresponding to all times, wherein the perfusion parameters comprise cerebral blood flow and a cerebral blood volume. According to the invention, the accuracy of blood perfusion parameter acquisition is improved.

Description

technical field [0001] The invention relates to the technical field of medical imaging, in particular to a method and system for obtaining blood perfusion of the hypothalamus and pituitary. Background technique [0002] Since Besedovsky first proposed the neuroendocrine immune network theory in 1977, the hypothalamus-pituitary-target gland axis has long been the core theoretical system and system model for the research on the physiology and disease of the endocrine system. The endocrine system, with the hypothalamus-pituitary-target gland axis as the core, affects the functions of the nervous and immune systems through various hormones, and regulates basic physiological functions such as nutrient metabolism, growth and development, and stress defense. [0003] At present, most hospitals in China are still unable to routinely measure pituitary hormones (such as the lack of TRH, CRH and other reagents), and cannot perform corresponding stimulation tests. For example: antidiur...

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Problems solved by technology

[0003] At present, most hospitals in China are still unable to routinely measure anterior pituitary hormones (such as the lack of TRH, CRH and other reagents), and cannot carry out corresponding stimulation tests

For example: antidiuretic hormone (AVP) is secreted by the supraoptic nucleus and paraventricular nucleus of the hypothalamus, and stored in the posterior pituitary gland. The measurement of AVP has certain value in the diagnosis of central diabetes insipidus. Although some hospitals in China have carried out detection, but More than 90% of AVP is bound to platelets, the concentration will be lower than the actual level, and the plasma AVP half-life is only 24min, poor stability, resulting in large fluctuations in detection, limiting clinical application

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