129 results about "Flow perfusion" patented technology

The invention relates to the technical field of health status assessment, in particular to a cardiovascular disease layered early warning system, which is characterized in that blood vessel compliance and pulse wave velocity are extracted, arterial dilation capacity is measured, blood vessel elasticity is calculated, blood perfusion distribution is detected, and abnormal vasoconstriction is classified on the basis of a hemodynamic state and a heart electrical activity state; in combination with the thickness of the blood vessel wall and the blood vessel stenosis rate, the plaque deposition condition is analyzed, the arteriosclerosis score is calculated, the thrombosis tendency is detected, the local blood flow blocking degree is quantified, the isolation forest algorithm is adopted, the blood flow dynamic change is calculated, the heart rhythm abnormality is analyzed, the acute vascular occlusion probability is measured, and the sudden heart rhythm abnormality risk is evaluated. And based on a gradient boosting tree algorithm, screening high-risk cases, matching medical intervention measures, setting a risk buffer mechanism, adjusting an individual health management strategy, and optimizing a cardiovascular risk hierarchical early warning system.

The invention provides a pilot brain consciousness state detection method, an electronic device and a detection system, which are applied to the technical field of biomedicine, and the method comprises the following steps: collecting a dual-channel photoelectric volume pulse wave signal of a forehead part of a to-be-detected pilot; determining a forehead blood oxygen value and a blood perfusion degree of the pilot to be detected based on the dual-channel photoelectric volume pulse wave signal; inputting the forehead blood oxygen value and the blood flow perfusion degree of the pilot to be detected into a pre-trained brain consciousness state score prediction model, so that the brain consciousness state score prediction model performs weighted calculation on the forehead blood oxygen value and the blood flow perfusion degree based on a pre-trained weight coefficient, outputting the brain consciousness state score of the pilot to be detected; and determining the brain consciousness state of the pilot to be detected based on the brain consciousness state score and a preset state score threshold. In this way, the brain consciousness state of the pilot can be comprehensively detected, and the accuracy of detecting the brain consciousness state of the pilot can be improved.

The invention discloses a shock wave forming device with a valve blood perfusion function, which relates to the technical field of medical instruments and comprises a catheter sheath, a shock wave forming balloon group, a shock wave generating component, a handle and a magnetic flexible net opening and closing structure. A guide wire is slidably arranged in the catheter sheath; the shock wave forming balloon set comprises a plurality of shock wave balloons, one ends of the shock wave balloons are connected with the end of the guide wire through flexible net-shaped structures, and the other ends of the shock wave balloons are connected with the end of the catheter sheath through flexible rod-shaped structures. The shock wave generating assembly comprises an axial shock wave generating electrode pair and a circumferential shock wave generating electrode pair; and the magnetic type flexible net opening and closing structure is arranged between the guide wire end part and the flexible net-shaped structure. The blood vessel can be mechanically supported or loosened; through the axial shock wave generation electrode pair and the circumferential shock wave generation electrode pair, the blocking plaque can be opened in the forward direction, and shock waves can be emitted in the circumferential direction to crack or crush calcium deposits; in addition, broken calcified plaques or aortic plaques, thrombus and the like can be captured.

The invention discloses a bedside skin flap blood flow monitoring and early warning device and computing equipment, and the device comprises a skin flap tissue perfusion monitoring module which comprises a probe housing, a microcirculation blood flow velocity sensor, a tissue oxygenation degree sensor and a flexible connecting arm; the data acquisition and transmission module is used for receiving the blood flow velocity data and the oxygenation degree data through a data line and carrying out analog-to-digital conversion and data packaging; the central processing unit comprises a data storage module, a data analysis module and an early warning module; the data analysis module comprises a baseline establishment sub-module, an anomaly detection sub-module and a trend prediction sub-module; and the early warning module is used for displaying a red alarm through a bedside display screen and sending a short message alarm containing the patient name, the bed number, the early warning type and the severity information to a medical staff mobile terminal through the wireless notification module. According to the invention, the abnormal condition of skin flap blood perfusion can be found and predicted in time, and the workload of medical staff is reduced.

The invention relates to the technical field of focus positioning, in particular to a hysteromyoma focus accurate positioning method combining image analysis and data fusion, which comprises the following steps: acquiring multi-modal uterus image data, and carrying out artifact suppression and spatial registration on an original image; performing three-dimensional reconstruction on the preprocessed multi-modal image data set to generate a three-dimensional uterus model comprising anatomical structure features; lesion feature segmentation is carried out in the three-dimensional uterus model, and morphological parameters and textural features of a myoma lesion are extracted; carrying out hemodynamic analysis to obtain blood perfusion parameters and blood vessel distribution characteristics of the focus area; the blood perfusion parameters and the blood vessel distribution characteristics are fused, the three-dimensional uterus model is combined, and a focus biomechanical characteristic distribution diagram is constructed; and generating a real-time navigation path according to the biomechanical characteristic distribution diagram, and outputting a positioning report. According to the method, personalized ablation energy suggestions are made, the ablation treatment efficiency and success rate are effectively improved, the ablation energy is dynamically adjusted, and the treatment efficiency and safety are ensured.

The invention relates to a blood flow quantitative analysis method and device based on an indocyanine green contrast video. The method comprises the steps that video data of indocyanine green fluorescence contrast are collected and preprocessed; extracting dynamic change characteristics of fluorescence intensity of the blood vessel region in the time sequence by adopting an optical flow model based on brightness change; introducing a weighted cross-correlation optical flow model, and extracting dynamic information of all blood vessel regions from each video frame; based on the optical flow vector and fluorescence intensity information of the blood vessel region, blood perfusion parameters are calculated, and a global blood perfusion pseudo-color graph is generated; and selecting a region of interest on the blood perfusion pseudo-color graph to obtain the change condition of the statistical fluorescence brightness value along with time in the region of interest, and drawing a time-brightness curve for presenting the dynamic change trend of the blood flow. Compared with the prior art, the global blood perfusion graph can be generated in real time, and the dynamic change of blood perfusion of all blood vessels can be visually displayed through the time-brightness curve.

The invention relates to the technical field of medical data processing and nerve regulation and control, in particular to a method for synchronously activating post-stroke neuroplasticity through photoacoustic, which comprises the following steps of: 1, constructing a stroke specific brain region target map: fusing brain structure connection data and functional network data of a patient, generating a three-dimensional target map containing the high-metabolism semi-dark band coordinate set and the cross-hemisphere compensatory connection intersection; 2, calculating a time-space synchronization focusing parameter; 3, synchronous stimulation and dynamic regulation are executed, wherein the ultrasonic transducer and the laser source are controlled to emit time-space synchronous sound waves and light pulses; monitoring the blood perfusion variable quantity and the neurotransmitter concentration ratio of the target brain area in real time; when the blood perfusion variable quantity does not reach the expectation or the transmitter ratio is unbalanced, the stimulation intensity is dynamically adjusted, and the focusing coordinate is translated in the direction away from the infarction area. Through photoacoustic stimulation of time-space synchronization, the difference between the propagation speeds of sound waves and light waves is overcome, and accurate collaboration of neural restoration is achieved.

The invention discloses a cold therapy method based on dynamic temperature feedback and intelligent adjustment, and the method comprises the steps: loading a cold therapy preset scheme from a database of a system, and carrying out the self-inspection of equipment of a sensing layer; collecting temperature distribution information of the skin surface of the treated part of the patient to obtain thermal imaging data; acquiring blood perfusion rate information; acquiring tissue moisture content and impedance phase angle information; establishing a temperature mapping relation from the skin surface to the deep tissue; the surface boundary condition is set as the skin surface temperature actually measured by the infrared array, and the deep boundary condition is set as an adiabatic hypothesis; and fusing the acquired multi-source observation data with the numerical solution result. The system has the advantages that accurate control over the cold therapy temperature is achieved, the protection response time is optimized, the safety of a patient in the cold therapy process is guaranteed, the treatment effect is improved, a doctor can conveniently make a personalized treatment scheme, efficient information interaction between the doctor and the patient is achieved, and the treatment experience of the patient is improved.

The invention provides a method for establishing a standard lung function image based on ventilation blood perfusion weight, which comprises the following steps of: acquiring a deformation field matrix and a gray value matrix by utilizing Python and 3Dslicer, and performing re-grading processing on the deformation field matrix and the gray value matrix to obtain a volume change matrix and a gray value change matrix; re-grading is carried out according to the graded volume change matrix and gray value change matrix to obtain a new lung function matrix, Matplotlib visualization of Python is utilized, region division is carried out on the new lung function matrix according to different function grades, and finally a function image based on ventilation-blood perfusion data is obtained. According to the quantitative analysis method for establishing lung function image segmentation based on the ventilation-blood perfusion weight of the 4D-CT and PET / CT images, the ventilation capacity and the blood perfusion capacity of the lung are considered at the same time, the conceptual defects in existing research are overcome, and the image conditions of different lung function areas can be reflected more accurately.

The invention relates to the technical field of image imaging, in particular to a blood perfusion imaging method and device based on EIT equipment, and the method comprises the steps: obtaining ventilation data in a monitoring period and a total impedance oscillogram corresponding to the ventilation data; selecting a first time period from the total impedance oscillogram, wherein the first time period is a time period during normal ventilation in the monitoring period; obtaining a first impedance oscillogram corresponding to the first time period and first total impedance waveform data corresponding to the first impedance oscillogram; generating a ventilation image according to the first total impedance waveform data; generating a blood perfusion impedance image according to the first total impedance waveform data and the total impedance oscillogram; and obtaining blood flow analysis data according to the ventilation image and the blood flow perfusion impedance image. According to the method, by processing the ventilation data and the total impedance oscillogram, the normal ventilation time period can be effectively recognized, the key impedance data can be extracted, then the accurate ventilation image and the blood perfusion impedance image are generated, and finally comprehensive and accurate blood flow analysis data are obtained.

The application provides a perfusion balloon catheter with a one-way valve, comprising: a balloon body part; the balloon body part comprises an inner lumen tube and a plurality of balloons arranged around the outer surface of the inner lumen tube; the distal balloon tube leg of the plurality of balloons is in contact with the tube wall of the inner lumen tube; a one-way valve is arranged between the inner lumen tube and the balloon part of the balloon. Compared with the prior art, the perfusion balloon catheter provided by the application is formed by a plurality of balloon clusters, and after expansion, a hollow cylindrical shape is formed, and a one-way valve is arranged in the cavity, which is used to simulate the leaflets in the heart valve, and the one-way valve is enabled after the balloon is opened, without the need for switching operation, and the structure is stable, and the function of the leaflets can be realized for multiple times; in addition, the design of the cluster balloon can reduce the difficulty of the balloon forming process while meeting the expected function.

The present invention belongs to the field of hemodialysis monitoring equipment, and provides a hemodialysis patient arteriovenous fistula function monitoring system and terminal equipment. The system comprises: an acquisition module, which is used to obtain the intensity of reflected light returned after detection light is irradiated to blood vessels under the skin of a human forearm, generate a current signal according to the reflected light, and convert the current signal into a measurement signal; a feature extraction module, which is used to obtain an intensity change sequence of the reflected light based on the measurement signal, separate a DC component and an AC component from the intensity change sequence, and obtain a blood perfusion index, a heart rate, and blood oxygen saturation, systolic pressure and diastolic pressure; a function evaluation module, which uses the maximum and minimum values ​​of the blood perfusion index, blood oxygen saturation, systolic pressure and diastolic pressure as first features, and adds heart rate as a second feature, and obtains the stenosis degree and blood flow of the blood vessel based on a machine learning classifier evaluation; the present invention can solve the problem in the prior art that the function of the arteriovenous fistula of a hemodialysis patient is difficult to intuitively monitor.

The invention relates to the technical field of stem cells, and particularly discloses application of mesenchymal stem cells (MSC) in treatment of lower limb vein ischemia. According to the application, the SDF1-FGF2 fusion protein is used for pretreating human mesenchymal stem cells (hMSCs), and the cell activity, the blood flow recovery capacity and the anti-inflammatory effect of the hMSCs in a lower limb vein ischemia model can be remarkably improved through pretreatment. The hMSCs pretreated by SDF1-FGF2 are injected into the body of a venous ischemia model mouse, and compared with untreated cells, the hMSCs have better effects in the aspects of improving blood perfusion, reducing inflammatory response, recovering motor function and the like. The method provides an efficient stem cell treatment strategy for vascular diseases such as lower limb vein ischemia.

The invention provides a high-definition vascular structure reconstruction and blood flow function evaluation method and system, and the method comprises the steps: constructing a high-dimensional feature manifold space based on an ultrasound contrast image, carrying out the recognition to obtain a vascular subgroup with different blood flow function modes, and finally obtaining a high-definition rainbow vascular structure video and a vascular heterogeneity index in an ultrasound scanning region. A powerful tool can be provided for evaluating tumor microvascular structures, blood flow functions and time-space heterogeneous characteristics, abundant parameters for quantitatively describing tumor complex vascular systems are provided for early evaluation of drug curative effects, and a target blood flow perfusion area can be specifically recognized according to functional characteristics; and a target prompt and feedback intervention basis is provided for drug targeted release.

The invention discloses a blood glucose data analysis system and method based on artificial intelligence, relates to the technical field of diabetes management, and aims to solve the problems of blood glucose data distortion and poor blood glucose monitoring suitability of gestational diabetes patients and children diabetes patients in a motion scene. The method comprises the following steps: acquiring blood glucose original data, exercise intensity data, skin impedance data, blood perfusion index data and special crowd exclusive physiological data, preprocessing, calculating three types of interference weight factors, substituting into a calibration formula to obtain corrected blood glucose data, generating a structured report, updating the calibration formula according to a period, and optimizing a special crowd model. By means of the method, motion multi-dimensional interference can be eliminated, the small sample modeling problem of special crowds is solved, and the blood glucose data precision and clinical practicability are improved.

The invention relates to a preparation method of exosome-like nano vesicles. The preparation method comprises the following steps: extracting beet juice; performing low-speed centrifugal treatment on the beet juice, and taking supernate; carrying out medium-speed centrifugation treatment on the supernatant obtained by low-speed centrifugation, and taking the supernatant; carrying out high-speed centrifugation treatment on the supernatant obtained by medium-speed centrifugation to obtain a precipitate containing exosome-like nano vesicles; and carrying out sucrose density gradient ultracentrifugation on the obtained precipitate containing the exosome-like nano-vesicles to obtain the purified exosome-like nano-vesicles. The BELNV prepared by the invention can significantly improve the survival rate of sepsis mice, increase blood perfusion of tissues and organs of the sepsis mice, reduce pathological changes, macrophage infiltration and fibrin deposition in lung and liver tissues of the sepsis mice, and reduce blood coagulation indexes and inflammation indexes. The invention provides a novel treatment target and strategy for a treatment means of sepsis-related blood coagulation dysfunction.

The invention belongs to the technical field of medical rehabilitation instruments and biological signals, and particularly relates to a multi-mode fusion intelligent rehabilitation evaluation system based on EMG and PPG. The system comprises a flexible multi-mode sensor array module used for collecting surface electromyogram signals EMG and photoelectric volume pulse wave signals PPG and capturing muscle activation intensity and blood perfusion dynamics in real time; the self-adaptive contact enhancing module is used for driving the airbag assembly to dynamically adjust the contact pressure between the embedded pressure sensor and the skin through the micro air pump; the edge calculation unit module is used for carrying out localization processing on the collected original signals, quantitatively evaluating the collaboration of muscle activity and blood flow fluctuation and judging whether muscle contraction drives local blood flow change or not or whether vessel limitation reversely inhibits neuromuscular activation or not; and the lightweight classification model module is used for processing the time-frequency characteristics of the EMG and the waveform fragments of the PPG, and outputting rehabilitation state labels after screening key collaborative characteristics through an attention mechanism.

The utility model discloses a splenic artery blood flow limiting support, and particularly relates to the technical field of medical instruments, the splenic artery blood flow limiting support comprises a supporting support and a flow limiting support, the supporting support is sleeved outside the flow limiting support, two ends of the flow limiting support are fixedly connected with the inner side wall of the supporting support, the flow limiting support is a covered stent, and the flow limiting support comprises a contraction section and an expansion section. The contraction section and the expansion section are fixedly connected and communicated, and splenic artery blood flow in the supporting stent flows in from the contraction section and flows out from the expansion section. The splenic artery embolism postoperative spleen blood perfusion can be reduced, and the recurrence of splenic hyperfunction is reduced.

The invention discloses a primary hypertension risk assessment method based on infrared thermal imaging. The method comprises the following steps: (1) respectively taking two-hand infrared thermograms of a healthy subject, a hypertension patient and a hypertension patient before and after cold stimulation by adopting a medical infrared thermal imager; (2) analyzing hand infrared thermograms before and after cold stimulation of a healthy subject, a hypertensive patient and a hypertensive patient so as to reflect vascular reactivity and blood perfusion states of hands of the healthy subject, the hypertensive patient and the hypertensive patient; and (3) taking hand infrared thermograms of the to-be-tested subject before and after cold stimulation by adopting a medical infrared thermal imager, and obtaining a judgment result according to the vascular reactivity and blood perfusion state of the hand. According to the invention, a medical infrared thermal imager is utilized to shoot infrared thermograms of hands of a subject before and after cold stimulation, so that vascular reactivity and blood perfusion states are visually reflected in a non-contact, real-time and visualized manner, and finally, the purpose of evaluating the risk of primary hypertension is achieved.

The embodiments of the present invention relate to the field of cryoablation and disclose a cryoablation temperature prediction method, device, electronic device and storage medium, including: constructing a vascular network diagram based on the vascular centerline in the three-dimensional imaging data before the cryoablation operation, the nodes in the vascular network diagram represent the vascular bifurcation points, and the blood edges represent the vascular connection relationship; during the cryoablation process, using a pre-trained temperature prediction model to predict the temperature field of the target sampling point, the temperature prediction model includes a physical information neural network and a graph neural network; the physical information neural network uses the biological heat conduction equation as a constraint condition to predict the temperature field of the target sampling point, and the graph neural network is used to predict the blood perfusion coefficient of each node in the vascular network diagram to determine the blood perfusion coefficient contained in the biological heat conduction equation, which solves the problem of real-time prediction of cryoablation temperature in accordance with physical laws, so that the results conform to physical laws and meet the real-time requirements during the operation.

This invention discloses an intelligent psychological guidance system for harmonizing the Qi of the internal organs based on TCM emotional differentiation, belonging to the field of medical electronic equipment. The system includes a multi-node physiological signal acquisition module, a central control and data processing module, and an acoustic intervention output module. The system synchronously acquires multi-channel bioimpedance, volumetric pulse wave, and electrocardiogram signals, extracts pulse wave conduction time and local blood perfusion index, constructs Qi characteristic parameters, and maps them to generate emotional tags. The central control module locks the target resonance unlocking frequency according to the tags, modulates low-frequency vibrations with reference audio to synthesize a multimodal signal, and further combines physiological pulse transmission delay to perform phase compensation, controlling the precise output of the intervention signal during ventricular diastole. Steady-state determination and closed-loop tracking are performed based on the dynamic gradient of impedance variance. This invention achieves objective quantification of TCM differentiation and ensures high-precision physical alignment between intervention energy and the hemodynamic state of the internal organs.

The invention relates to the technical field of disease analysis, and provides an acute-stage cerebral infarction detection system and method.The method comprises the steps that basic information, physical sign data and blood sample data of a brain patient are collected, and data integration is conducted to obtain integrated data; a brain scanning image is obtained, and a high-definition brain image is obtained after artifacts are removed; recognizing image semantics, performing image segmentation, evaluating a segmentation level, and obtaining a target image when a preset level is met; identifying brain lesion features by using the target image; an angiogram is collected, the brain blood vessel caliber is calculated, and the brain blood perfusion condition is analyzed; constructing a blood vessel network by using the angiogram, and analyzing a blood vessel variation degree; based on the blood vessel caliber, the blood perfusion condition and the blood vessel variation degree, analyzing the brain blood vessel lesion degree; collecting an electroencephalogram, and analyzing brain activity characteristics; and performing acute-stage cerebral infarction analysis based on the integrated data, the brain lesion features, the brain vascular lesion degree and the brain activity features. The invention aims to improve the rationality of acute cerebral infarction detection.

The invention discloses an HMPB / FA nano system with multienzyme activity and a preparation method of the HMPB / FA nano system, and belongs to the technical field of biological medicines. The method comprises preparation of mesoporous prussian blue PB, hollow mesoporous prussian blue HMPB and an HMPB / FA nano system with multienzyme activity, and is simple in preparation, high in synthesis efficiency, low in cost, good in repeatability and efficient in drug utilization rate. The HMPB / FA nano-system prepared by the invention takes HMPB with a hollow mesoporous structure as a carrier, ferulic acid FA is loaded by a solution impregnation method, and the HMPB / FA nano-system has good multi-enzyme activity and has no obvious cytotoxicity to C2C12 and RAW264.7 cells. The HMPB / FA nano system prepared by the invention is applied to treatment of lower limb ischemia diseases, can obviously improve related symptoms (including weight loss and blood perfusion) of lower limb ischemia, and solves the problems of various inflammatory reactions caused by lower limb ischemia, defects in the prior art and the like.

This application relates to the field of biomedical engineering technology. This application discloses a method, device, terminal device and storage medium for dual-foot sole video evaluation based on plantar perfusion imaging, which can improve the accuracy of evaluation results, simplify the measurement process and enhance the patient experience. The method includes obtaining a dual-foot sole video; obtaining a plurality of left plantar rPPG signals and a plurality of right plantar rPPG signals based on the dual-foot sole video; drawing a plurality of dual-foot sole perfusion maps based on the plurality of left plantar rPPG signals and the plurality of right plantar rPPG signals; generating a target image based on the plurality of dual-foot sole perfusion maps; extracting the average value, standard deviation, maximum value and minimum value of the blood perfusion index ratio from the target image and inputting them into a classifier for evaluation processing to obtain an evaluation result, and medical staff refer to the evaluation result to diagnose peripheral artery disease and its severity.

Enhanced Thermal Imaging (ETI) is an infrared imaging modality (8-10 μm) that uses heat as a contrast agent to detect microvasculature (vessel size 0.1-5 mm) embedded in soft tissue. ETI uses an LED (535 nm±30 nm or 405 nm±30 nm) to selectively heat embedded blood vessels causing the blood to heat by approximately 0.5° C. relative to the surrounding water-rich tissue. The selective heating increases contrast in the enhanced thermal image revealing embedded microvasculature and associated blood flow.

The present invention relates to the field of stem cell technology and specifically discloses an application of mesenchymal stem cells (MSCs) for the treatment of lower extremity venous ischemia. This application involves pre-treating human mesenchymal stem cells (hMSCs) with the SDF1-FGF2 fusion protein. This pre-treatment significantly enhances the cell viability, blood flow recovery, and anti-inflammatory effects of hMSCs in a lower extremity venous ischemia model. When hMSCs pre-treated with SDF1-FGF2 were injected into mice modeling venous ischemia, they demonstrated superior effects compared to untreated cells in improving blood perfusion, reducing inflammatory responses, and restoring motor function. This method provides a highly effective stem cell therapy strategy for vascular diseases such as lower extremity venous ischemia.

This application relates to a coronary sinus and left atrium shunt system, belonging to the field of medical device technology. The system described in this application, by setting up a puncture component and a shunt component including a cutter, allows for the cutting of a portion of myocardial tissue between the coronary sinus and the left atrium, forming a shunt orifice. This establishes a shunt channel between the coronary sinus and the left atrium, effectively avoiding the embolism risk associated with atrial septal shunts and improving coronary artery blood perfusion, potentially benefiting myocardial recovery.

The utility model relates to the technical field of medical instruments, and provides an intervention guiding catheter and an intervention system.The intervention guiding catheter comprises a catheter body, a switch assembly and a traction piece; a side hole is formed in the catheter body and penetrates from the outer wall of the catheter body to the inner wall of the catheter body; the switch assembly comprises a switch piece, and the switch piece is arranged on the catheter body; the traction piece is connected with the switch piece, and the traction piece is used for pulling at least one part of the switch piece to move relative to the catheter body so as to open or close the side hole. According to the intervention guiding catheter, the side hole is provided with the switch for controlling the side hole to be opened or closed, by controlling the switch of the side hole, the side hole of the intervention guiding catheter with the side hole is opened when needed, and blood perfusion of a target blood vessel is provided for a target object; when the side hole is not needed, the side hole is closed, the usage amount of the contrast agent is reduced, and meanwhile the supporting force of the side hole specification interventional guiding catheter is improved.

The invention relates to a pump blood driving mechanism of a blood pump, the blood pump and a ventricular assist system. The blood pumping driving mechanism comprises a paddle assembly and a driving assembly. The blade assembly has a first form and a second form, and the maximum radial size of the blade assembly in the first form is larger than the maximum radial size of the blade assembly in the second form; the driving assembly can drive the paddle assembly to axially stretch out and draw back in a reciprocating mode so that the paddle assembly can be switched between the first form and the second form in turn, and then the paddle assembly can conduct blood pumping operation. The blood pumping driving mechanism can effectively reduce the shearing force on blood cells, so that the hemolysis risk is greatly eliminated, meanwhile, the clinical application time and stability of the product are greatly improved, and the effects of low-frequency operation and high blood perfusion can be achieved.

The utility model relates to an alternating tangential flow perfusion system and a control method thereof, and the alternating tangential flow perfusion system comprises a consumable component, a weighing component, an air inflation component, an air exhaust component and a control box, the consumable assembly is arranged on the weighing assembly, the weighing assembly is used for monitoring the weight of fluid in the consumable assembly in real time, the control box judges the motion state of the elastic balloon according to the variable quantity of the fluid weight and the change rate of the fluid weight, and then the working states of the air inflation assembly and the air exhaust assembly are controlled; according to the alternating tangential flow perfusion system and the control method thereof, the defects in the prior art are overcome, and system operation is more stable and reliable.