60 results about "Flow perfusion" patented technology

The invention discloses a blood glucose data analysis system and method based on artificial intelligence, relates to the technical field of diabetes management, and aims to solve the problems of blood glucose data distortion and poor blood glucose monitoring suitability of gestational diabetes patients and children diabetes patients in a motion scene. The method comprises the following steps: acquiring blood glucose original data, exercise intensity data, skin impedance data, blood perfusion index data and special crowd exclusive physiological data, preprocessing, calculating three types of interference weight factors, substituting into a calibration formula to obtain corrected blood glucose data, generating a structured report, updating the calibration formula according to a period, and optimizing a special crowd model. By means of the method, motion multi-dimensional interference can be eliminated, the small sample modeling problem of special crowds is solved, and the blood glucose data precision and clinical practicability are improved.

This invention discloses an intelligent psychological guidance system for harmonizing the Qi of the internal organs based on TCM emotional differentiation, belonging to the field of medical electronic equipment. The system includes a multi-node physiological signal acquisition module, a central control and data processing module, and an acoustic intervention output module. The system synchronously acquires multi-channel bioimpedance, volumetric pulse wave, and electrocardiogram signals, extracts pulse wave conduction time and local blood perfusion index, constructs Qi characteristic parameters, and maps them to generate emotional tags. The central control module locks the target resonance unlocking frequency according to the tags, modulates low-frequency vibrations with reference audio to synthesize a multimodal signal, and further combines physiological pulse transmission delay to perform phase compensation, controlling the precise output of the intervention signal during ventricular diastole. Steady-state determination and closed-loop tracking are performed based on the dynamic gradient of impedance variance. This invention achieves objective quantification of TCM differentiation and ensures high-precision physical alignment between intervention energy and the hemodynamic state of the internal organs.

This application relates to a coronary sinus and left atrium shunt system, belonging to the field of medical device technology. The system described in this application, by setting up a puncture component and a shunt component including a cutter, allows for the cutting of a portion of myocardial tissue between the coronary sinus and the left atrium, forming a shunt orifice. This establishes a shunt channel between the coronary sinus and the left atrium, effectively avoiding the embolism risk associated with atrial septal shunts and improving coronary artery blood perfusion, potentially benefiting myocardial recovery.

The invention relates to the technical field of biology, in particular to a method for modular assembly of artery blood vessel type organs and construction of tissue microcirculation of the artery blood vessel type organs. The method comprises the following steps: inducing human pluripotent stem cells to differentiate through a mesoderm stage to form an arterial specific vascular organoid module (AVO), and then carrying out modular assembly on the AVO in vivo or in vitro so as to quickly reconstruct a tissue microcirculation network with arterial characteristics. The obtained artery blood vessel organoid is uniform in form, the diameter of the artery blood vessel organoid is intensively distributed at about 200 microns, SOX17 and CXCR4 artery endothelial markers are expressed at the same time, and the artery blood vessel organoid has polarity and a complete basilar membrane. Transplanting experiments show that the organ can be integrated with host blood vessels in a short time, and ischemic tissue blood perfusion is recovered. The defects that existing organoid is irregular, difficult to splice, delayed in perfusion and the like are overcome, and a new strategy is provided for revascularization and acute ischemic disease repair.

The application discloses a bladder cancer diagnosis and treatment integrated system and a control method thereof, which comprises a swept-frequency OCT light source, a treatment laser, a wavelength division multiplexer, a double-clad optical fiber, a flexible scanning probe, an endoscope imaging unit and an intelligent image processing and control terminal; imaging light and treatment laser are transmitted in a common light path by using the double-clad optical fiber, and scanning and light beam control are completed by means of a double-axis MEMS micro-mirror. The control method obtains tomographic structure information and depth information by reconstructing OCT data, and controls treatment laser power, galvanometer deflection and laser pause, recovery or stop by combining distance calculation, displacement compensation and blood perfusion monitoring, and is suitable for imaging navigation and closed-loop treatment in bladder cancer surgery.

The application discloses a lung ventilation-perfusion imaging area three-dimensional blood flow distribution abnormality analysis method, relates to the technical field of lung function quantitative evaluation, and comprises the following steps: acquiring lung CT image data of a patient to be analyzed, performing structure segmentation on a plurality of sections of the lung CT image data to obtain ventilation phase gray scale images and blood flow perfusion phase gray scale images; on the basis of the lung CT image data, accurately extracting a non-black lung region by threshold segmentation, respectively calculating the ratio of ventilation CT values and blood flow CT values in the region, and generating lung region segmentation data; based on the three-dimensional V / Q ratio atlas, identifying abnormal sub-regions in which local ventilation blood flow ratios deviate from physiological ranges; and obtaining a blood flow distribution abnormality analysis report by performing structured analysis on the abnormal sub-regions. The application divides irregular sub-regions by performing a K-means clustering algorithm on gray scale values in each section, realizes adaptive segmentation of lung function heterogeneity structures, and improves the rationality of local ratio calculation.

The invention discloses a coronary medicine balloon dilatation catheter, and belongs to the technical field of medical instruments. In order to solve the problems that an existing drug balloon is high in blood flow blocking risk, large in drug loss and uneven in drug distribution, the balloon dilatation catheter comprises a catheter body, a dilatation balloon, a drug delivery catheter, a drug storage bin, a driving connecting rod, a connecting ring and a guiding head. The dosing catheter protrudes out of the periphery of the dilatation balloon at intervals, the flexible side wall of the medicine storage bin communicates with the liquid injection cavity channel, and the driving connecting rod drives the dosing catheter to rotationally apply medicine through spiral transmission; the catheter body is provided with an independent blood flow cavity channel and a blood inlet, and a gap formed by the catheter body and the administration catheter forms a double-channel blood flow path. The invention realizes the synergy of vasodilatation, accurate and uniform administration and continuous blood perfusion, reduces drug loss and non-targeted deposition, reduces myocardial ischemia complications and postoperative restenosis risk, is simple and convenient to operate, and is suitable for various coronary heart disease treatment scenes.

The invention provides a stroke risk time sequence management-oriented multi-modal data-driven acupoint regulation and self-optimization intervention method and system, and relates to the technical field of medical health information processing. The skin temperature, the heart rate, the infrared blood perfusion, the activity intensity and the sleep state are continuously collected, data cleaning and feature modeling are carried out, a prediction model is trained in combination with historical intervention results, and the optimal intervention opportunity, duration and safety boundary of the day are generated; acupuncture points and execution units are determined according to a planned object, physiological signals are collected in real time, the slow release rate or stimulation intensity is dynamically adjusted, and control is conducted through safety boundary and dose constraint; the risk and stability are calculated based on data and adjustment records before, during and after intervention, a prediction model is updated, a plan of the next day is generated, individualized closed-loop management of monitoring, decision making, execution and feedback is achieved, and the safety and effectiveness of stroke risk intervention are improved.

The application provides a myocardial infarction detection system based on diffusion speckle, and relates to the field of wearable health detection.The system comprises a laser for exciting a laser signal;an optical fiber probe connected with the laser through a multimode optical fiber for guiding the laser signal to a to-be-detected object and collecting a reflected light signal of the to-be-detected object;a camera connected with the optical fiber probe through a multimode optical fiber for obtaining a diffusion speckle image based on the reflected light signal;and a processing device electrically connected with the camera for obtaining an initial blood perfusion index signal and an initial pulse wave signal based on the diffusion speckle image, reconstructing the initial blood perfusion index signal and the initial pulse wave signal respectively to obtain a target blood perfusion index signal and a target pulse wave signal, and performing myocardial infarction detection based on the target blood perfusion index signal and the target pulse wave signal.

This invention relates to the field of medical device technology and discloses a multifunctional auxiliary device for thyroid surgery, comprising: a base; a tension band; a binding block; a base component connected to the binding block, the base component including a fixed ring and a movable ring, the fixed ring being connected to the binding block, the movable ring being rotatably mounted on top of the fixed ring, and the movable ring being coaxial with the fixed ring; traction components, with several sets of traction components mounted on the movable ring; and a drive mechanism. By setting a rotatable movable ring and multiple sets of traction components, during surgery, the drive mechanism drives the movable ring to rotate intermittently in both directions, causing several rotating rods to intermittently change positions at the incision site, thereby continuously changing the stress points of the incision tissue. This allows tissues in different areas to take turns bearing the traction force and receiving blood perfusion, effectively avoiding local tissue ischemia, hypoxia, and plastic deformation caused by stress concentration in traditional traction devices, significantly protecting tissue activity, and promoting postoperative healing.

The invention relates to a prediction model training method for acquiring blood perfusion maps of keloids, which comprises the following steps of: acquiring a sample data set, preprocessing the sample data set, acquiring a training data set comprising a training set and a test set, and samples of which each sample is pix2pix, including a true general image and a true blood perfusion map to which the true general image belongs; a true segmentation image of the general image; respectively inputting the three images of each sample into four corresponding generators in a pre-constructed TripleGAN neural network, and acquiring total loss information by three discriminators based on the outputs of the four generators and the corresponding images in the samples; and further training and testing the TripleGAN neural network to obtain the trained TripleGAN neural network, and taking a generator for receiving the general image and outputting the blood perfusion map in the TripleGAN neural network as a trained prediction model. According to the method, the problems that existing medium scale evaluation is inaccurate, and LSCI evaluation is high in cost and wastes time and labor are solved.

The present application relates to the field of electrical impedance imaging, and discloses a regional lung perfusion delay time analysis method, an electronic device and a storage medium. A dynamic image of conductivity change caused by blood perfusion in a human thoracic cavity is obtained. A blood perfusion image of a heart region and a blood perfusion image of a lung region are separated. A reference curve of conductivity change of the heart region is obtained according to the dynamic image of blood perfusion conductivity change and the blood perfusion image of the heart region. A conductivity change curve of each pixel point in the blood perfusion image of the lung region is obtained according to the dynamic image of blood perfusion conductivity change and the blood perfusion image of the lung region. The conductivity change curve is divided by a sliding time window, and a regional lung perfusion delay time is calculated in each time window. The time resolution advantage of electrical impedance imaging technology is fully utilized, and the time delay of the time when the local blood volume of the lung reaches the maximum relative to the end of the ventricular diastole is reflected by calculating the regional lung perfusion delay time.

The invention discloses a door lock control method and device and an intelligent door lock, the method is applied to the intelligent door lock, and the method comprises the following steps: obtaining a to-be-recognized image, and analyzing the to-be-recognized image to obtain facial feature data of a global face; and processing the facial feature data to obtain a blood perfusion index. Acquiring to-be-processed pulse data of the target user, and processing the to-be-processed pulse data to obtain pulse characteristic parameters. And inputting the blood perfusion index and the pulse characteristic parameter into a preset characteristic fusion model to obtain a control instruction of the intelligent door lock. According to the control instruction, the intelligent door lock is controlled to give out an early warning prompt. According to the door lock control method, signal acquisition and analysis from multiple dimensions are achieved, so that the intelligent door lock is controlled more comprehensively and accurately, finally, early warning prompt is triggered based on the control instruction, accurate and normalized monitoring of the home state of a user is achieved, and effective guarantee is provided for home safety of the user.

This application provides a method, device, system, and medium for monitoring blood perfusion. The method includes: acquiring a speckle image sequence of the tissue region to be monitored based on a laser emitted to it; acquiring ambient light information corresponding to the speckle image sequence and motion information between adjacent speckle images in the speckle image sequence; performing anti-interference processing on the speckle image sequence based on the ambient light information and the motion information between adjacent speckle images to obtain a corrected speckle image sequence; calculating the spatiotemporal joint speckle contrast of the corrected speckle image sequence to obtain a spatiotemporal joint speckle contrast; determining the blood perfusion parameters of the tissue region to be monitored based on the spatiotemporal joint speckle contrast using a pre-established mapping model between speckle contrast and blood perfusion parameters; and outputting a warning message when the blood perfusion parameters meet preset warning conditions. This method aims to improve the accuracy of blood perfusion monitoring.

The invention relates to the field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for preventing and treating sequelae of a damp-heat stasis type pelvic inflammatory disease and application of the traditional Chinese medicine composition. The traditional Chinese medicine composition is prepared from traditional Chinese medicinal materials such as hairyvein agrimony, angelica sinensis, rhizoma smilacis glabrae, cortex phellodendri, zaocys dhumnade, salvia miltiorrhiza, herba lycopi and vinegar-processed bupleurum yunnanense according to a certain weight ratio, wherein the hairyvein agrimony serves as a monarch The traditional Chinese medicine composition can synergistically regulate inflammatory response, reduce the level of proinflammatory factors, improve the expression of anti-inflammatory factors, improve the immune state of a body, remarkably improve local blood perfusion of pelvic cavity and promote repair of a uterus tissue structure. Compared with antibiotic drugs, the traditional Chinese medicine composition disclosed by the invention has more outstanding technical effects in the aspects of improving pelvic blood flow and repairing tissues, and also has a good protection effect on uterine epithelial cells in an inflammatory state. The invention further provides enema liquid prepared from the traditional Chinese medicine composition, a rectal administration preparation and application of the enema liquid and the rectal administration preparation. The traditional Chinese medicine composition provided by the invention is good in safety and clear in action mechanism, can be used for preparing related medicines for preventing and treating damp-heat stasis type pelvic inflammatory disease sequelae, and has a good application prospect.

The application provides a high-definition blood vessel structure reconstruction and blood flow function evaluation method and system, constructs a high-dimensional feature manifold space based on an ultrasonic contrast image, identifies a blood vessel subgroup with different blood flow function modes, finally obtains a high-definition rainbow blood vessel structure video and a blood vessel heterogeneity index in an ultrasonic scanning area, can not only provide a powerful tool for evaluating tumor microvessel structure, blood flow function and spatiotemporal heterogeneity characteristics, provide rich parameters for quantitatively describing a complex blood vessel system of a tumor for early evaluation of drug efficacy, and can specifically identify a target blood perfusion area according to a function characteristic, provide a target prompt and feedback intervention basis for drug targeted release.

The invention discloses a therapeutic instrument temperature real-time monitoring method based on an intelligent sensor. According to the method, a personalized finite element model is constructed by collecting a three-dimensional medical image and real-time sensing data of a patient; forward calculating a theoretical three-dimensional temperature field based on a biological heat transfer model; fusing and correcting the theoretical temperature field and the real-time treatment parameters by using a data assimilation algorithm to obtain an accurate real-time three-dimensional temperature field and a corrected blood perfusion rate; on this basis, the system further calculates a three-dimensional thermal dose field, carries out risk assessment in combination with a real-time temperature field, and finally generates a predictive alarm and closed-loop control instruction; the method has the core advantages that a physical model and sparse sensing data are deeply fused, a digital thermal field model synchronous with physiological characteristics of a patient is constructed, crossing from point temperature measurement to body monitoring is achieved, temperature distribution of a whole treatment area can be comprehensively and accurately predicted in real time, and a monitoring blind area is eliminated.

The utility model provides an aortic arch covered stent in-situ fenestration internal bypass catheter which comprises a catheter body, a near-end developing structure and a far-end developing structure, and a main channel and a bypass channel which are isolated from each other are arranged in the catheter body; the main channel penetrates through the pipe body in the axial direction. The flow turning channel is located on one radial side of the main channel and comprises a near-end opening and a far-end opening which are formed in the side wall of the pipe body, and a flow channel communicating the near-end opening with the far-end opening; the near-end developing structure is arranged on the side wall of the tube body and surrounds the edge of the near-end opening; the far-end developing structure is arranged on the side wall of the tube body and surrounds the edge of the far-end opening; the near-end developing structure and the far-end developing structure are different in shape, a temporary channel of the aorta true cavity and the arch branch is established, and continuous blood perfusion is provided for the brain.

This invention relates to the field of medical monitoring equipment technology, specifically disclosing a magnetically positioned flap monitoring device, system, and method. The invention achieves a stable fit between the medical adhesive layer on the bottom surface of the base dressing layer and the skin surface of the flap area. Utilizing the magnetic attraction between the first magnet group on the magnetic docking ring and the second magnet group on the flexible sensing patch, a modular sensing connection architecture that can be repeatedly assembled and disassembled is constructed. This solves the problems of traditional adhesive tape or suture fixation methods, which are prone to probe slippage due to skin sweating or changes in body position, causing monitoring interruptions. It also addresses the lack of a unified spatial positioning benchmark in multi-probe collaborative layouts, making it difficult to achieve systematic mapping of blood perfusion in the flap area. This improves the continuity and stability of postoperative flap monitoring and enhances the ability of the optical sensor array to capture information on the overall spatial distribution of blood perfusion in the flap.

The invention relates to a multi-mode-based traditional Chinese medicine external curative effect fruit detection method and system, and belongs to the technical field of medical detection. The method comprises the following steps: acquiring infrared thermal imaging, laser speckle blood perfusion, skin conductance and body surface temperature signals of a traditional Chinese medicine external application area of a subject, performing time synchronization, noise suppression and spatial registration, and inputting the signals into a multi-modal fusion model to generate a fusion feature vector; calling preset physiological response reference data, comparing the fused feature vector with the first comparison result data and the second comparison result data respectively, generating first comparison result data and second comparison result data, and generating physiological response intensity data according to the first comparison result data and the second comparison result data; and further inputting the intensity data of continuous time periods into a trend prediction model, outputting physiological response trend data in a future time window, and realizing objective, real-time, quantitative and predictable monitoring of local physiological state changes under the action of external application of the traditional Chinese medicine through multi-dimensional signal fusion and double-reference dynamic comparison.

The application discloses a kind of to the consciousness level evaluation system for wounded person, it is related to personnel consciousness evaluation grading technical field, including the acquisition module for obtaining the electroencephalogram signal and the photoplethysmogram signal of two channels of brain of wounded person, the digitization processing module of corresponding module electric signal digitization conversion, feature extraction module extracts time domain feature, frequency domain feature and entropy from electroencephalogram digital signal, from the ratio of pulse wave digital signal, calculate blood oxygen saturation and calculate blood perfusion index, consciousness evaluation module passes through fusion feature vector input consciousness state assessment model, output continuous consciousness state score, and with multiple threshold mapping obtains consciousness grade.The system of the application carries out time domain, frequency domain and nonlinear analysis respectively in the feature extraction of electroencephalogram signal and pulse wave signal, and blood oxygen and blood perfusion degree calculation, realizes the quantitative description and grading determination to the consciousness level of wounded person.

Embodiments of the present application provide a kidney state evaluation device, method, equipment, storage medium and program product. In the device: a obtaining module obtains a kidney structure image, an RBF image and a T1Map; a registration module performs image registration on the kidney structure image, the RBF image and the T1Map to obtain a target kidney structure image, a target RBF image and a target T1Map; a segmentation module segments the target kidney structure image by using a trained kidney segmentation model to obtain a segmentation mask of the renal parenchyma, renal cortex and renal medulla respectively; a processing module determines the morphology of the renal parenchyma from the target kidney structure image, determines the blood perfusion values of the renal cortex and the renal medulla from the target RBF image, and determines the T1 relaxation times of the renal cortex and the renal medulla from the target T1Map based on the segmentation mask; and an evaluation module evaluates the kidney state according to the processing result. The scheme provided in the embodiments of the present application can improve the accuracy of kidney state evaluation.

The invention discloses a missing modal medical image segmentation method and device based on time-varying representation decoupling, and relates to the technical field of medical image processing and computer-aided diagnosis. The method comprises the following steps: constructing a medical image segmentation model based on time decay characterization decoupling; inputting the multi-modal medical images into a shared encoder to obtain a feature map sequence; obtaining discretized static anatomical features by querying a learnable embedded dictionary in the static path; performing regression prediction on relative time parameters of the feature map sequence of each channel through a regression network in the dynamic path, and determining dynamic enhancement features for representing tissue blood perfusion by taking the static anatomical features and the relative time parameters as conditions; performing weighted fusion on the static anatomical features and the dynamic enhanced features; and inputting the fusion feature into the segmentation head to obtain a segmentation mask result of the target tumor. According to the invention, through a decoupling architecture of physical perception, the segmentation performance is improved.

The present invention relates to an alternating tangential flow perfusion system and a control method therefor. The alternating tangential flow perfusion system comprises: a consumable assembly, a weighing assembly, an inflation assembly, a gas extraction assembly, and a control box, wherein the consumable assembly is disposed on the weighing assembly, the weighing assembly is used for monitoring the weight of a fluid in the consumable assembly in real time, and the control box determines the motion state of an elastic balloon on the basis of the variation of the weight of the fluid and the rate of change of the weight of the fluid, so as to control the operating states of the inflation assembly and the gas extraction assembly. The alternating tangential flow perfusion system and the control method therefor are provided in order to overcome existing defects, such that the operation of the system is more stable and reliable.

The application relates to the technical field of blood flow detection, and discloses a cerebral blood flow detection method and device, which comprises the following steps: acquiring detection signals corresponding to multiple brain regions of a target head; determining a to-be-processed signal in a current sliding window in the detection signals; pre-processing the to-be-processed signal to obtain a cerebral blood flow dynamic parameter time sequence corresponding to each brain region; determining a cerebral blood flow activity index, a cerebral blood flow coordination index and a left-right hemisphere symmetry index based on the cerebral blood flow dynamic parameter time sequence; the cerebral blood flow activity index is used for representing the active degree of cerebral blood flow of the whole brain, the cerebral blood flow coordination index is used for representing the cerebral blood flow coordination between brain regions, and the left-right hemisphere symmetry index is used for representing the symmetry change of blood flow perfusion and blood flow regulation between the left and right hemispheres. Through the sliding window technology and real-time signal processing, the application can realize rapid monitoring of the dynamic change of cerebral blood flow, and can comprehensively evaluate the functional state of the brain region and the mutual relationship from multiple dimensions.

The invention relates to a computer-implemented method for determining a cardiovascular performance (2). The method comprises receiving a plurality of measurement data (5) through a communication interface (6) from a sensor (7) at a measurement section (41) of the patient's distal periphery (4). The measurement data (5) provides information about a perfusion of the blood flow at the measurement section (41). The plurality of measurement data (5) comprises at least two different measurement data (5) detected at different times after the blood flow to the distal periphery (4) has been restored. The method further comprises determining the cardiovascular performance (2), in particular the cardiac output, based on the plurality of measurement data and providing output data by an output interface (8) comprising the cardiovascular performance (2).

The application relates to a blood pumping driving mechanism of a blood pump, the blood pump and a ventricular assist system. The blood pumping driving mechanism comprises a paddle assembly and a driving assembly; the paddle assembly has a first mode and a second mode, the maximum radial dimension of the paddle assembly in the first mode is greater than that in the second mode; the driving assembly can drive the paddle assembly to reciprocate axially to switch the paddle assembly between the first mode and the second mode, so that the paddle assembly can perform a blood pumping operation. The blood pumping driving mechanism can effectively reduce the shearing force on blood cells, thereby greatly eliminating the risk of hemolysis, and the clinical application time and stability of the product are greatly improved, and the effects of low-frequency operation and high blood perfusion can be realized.

The invention provides an intelligent self-adaptive perineum moxibustion therapy system and method. The intelligent self-adaptive perineum moxibustion therapy system comprises a dynamic force field generation unit, a multi-physical field cooperation unit, a multi-modal physiological sensing unit and an intelligent closed-loop control unit, the intelligent closed-loop control unit is configured to execute the following closed-loop control logic: based on the subcutaneous blood perfusion signal, calculating a physiological response index representing tissue energy metabolism and microcirculation states in real time; based on the dynamic mechanical interaction signal, calculating a fascia debonding index representing viscoelasticity and debonding degree of fascia tissue in real time; a current strategy area is determined according to the real-time physiological response index and the fascia debonding index, a collaborative strategy vector corresponding to the current strategy area is called, and the collaborative strategy vector integrally defines a target parameter combination of a dynamic mechanical force field, an infrared radiation field, an airflow field and a sound wave field and a linkage relation of the target parameter combination; and according to the collaborative strategy vector, generating a control instruction to adjust each physical field parameter.

The invention provides application of an NCOA3 polyQ structural domain as a target spot in preparation of a medicine for relieving lower limb ischemic diseases, relates to the technical field of biomedicine, and aims to solve the problems that in the prior art, blood flow reperfusion recovery of the lower limb ischemic diseases is poor, collateral vessels are insufficient in formation, and safe and effective targeted intervention means are lacked. By constructing a mouse lower limb ischemia model, it is proved that blood flow recovery and collateral angiogenesis after ischemia are remarkably inhibited by Nco3polyQ structural domain deletion: compared with a WT mouse, postoperative blood flow perfusion of an Nco3Q / Q mouse is recovered slowly, and the blood flow of the affected side is only recovered by 60% on the 21st day after the operation; the CD31 positive region of the gastrocnemius muscle tissue on the 14th day after the operation is obviously reduced, and the mRNA expression of the blood vessel marker gene Pecam1 is reduced. On the basis, an intervention strategy aiming at the NCOA3 polyQ structural domain is used for preparing the medicine for relieving the lower limb ischemic disease, and a new treatment strategy and a potential target are provided for the ischemic limb disease.

The invention belongs to the technical field of obstetrical nursing, and particularly relates to an obstetrical nursing abdominal pressure device which comprises a bed. Through the design of the adjusting mechanism and the linkage of components such as a gear and a gear ring, a first rectangular rack is driven to move in a first sliding groove in the radial direction, precise adjustment of the pressing point range is achieved, and the defect that a traditional abdominal pressure device is cut at a time is overcome for patients with different body types; through the design of the vibration mechanism and the mechanical transmission of the eccentric turntable, the push rod and other components, the generated resonant frequency enables the uterine muscle layer to generate periodic micro-vibration, so that the blood perfusion rate can be increased, and the removal of metabolic wastes can be accelerated; through the design of a pressing mechanism, meshing of a worm and a worm gear and precise driving of a third stepping motor, rotary motion is converted into linear displacement of a second rectangular rack, and through the linkage design of a spring and a pressure sensor, the defects that air bag type adjustment depends on air pump pressure and is prone to being affected by temperature are overcome; according to the design, more stable pressure application control is realized through rigid mechanical transmission.