107 results about "Flow perfusion" patented technology

The invention relates to the technical field of health status assessment, in particular to a cardiovascular disease layered early warning system, which is characterized in that blood vessel compliance and pulse wave velocity are extracted, arterial dilation capacity is measured, blood vessel elasticity is calculated, blood perfusion distribution is detected, and abnormal vasoconstriction is classified on the basis of a hemodynamic state and a heart electrical activity state; in combination with the thickness of the blood vessel wall and the blood vessel stenosis rate, the plaque deposition condition is analyzed, the arteriosclerosis score is calculated, the thrombosis tendency is detected, the local blood flow blocking degree is quantified, the isolation forest algorithm is adopted, the blood flow dynamic change is calculated, the heart rhythm abnormality is analyzed, the acute vascular occlusion probability is measured, and the sudden heart rhythm abnormality risk is evaluated. And based on a gradient boosting tree algorithm, screening high-risk cases, matching medical intervention measures, setting a risk buffer mechanism, adjusting an individual health management strategy, and optimizing a cardiovascular risk hierarchical early warning system.

The invention discloses a shock wave forming device with a valve blood perfusion function, which relates to the technical field of medical instruments and comprises a catheter sheath, a shock wave forming balloon group, a shock wave generating component, a handle and a magnetic flexible net opening and closing structure. A guide wire is slidably arranged in the catheter sheath; the shock wave forming balloon set comprises a plurality of shock wave balloons, one ends of the shock wave balloons are connected with the end of the guide wire through flexible net-shaped structures, and the other ends of the shock wave balloons are connected with the end of the catheter sheath through flexible rod-shaped structures. The shock wave generating assembly comprises an axial shock wave generating electrode pair and a circumferential shock wave generating electrode pair; and the magnetic type flexible net opening and closing structure is arranged between the guide wire end part and the flexible net-shaped structure. The blood vessel can be mechanically supported or loosened; through the axial shock wave generation electrode pair and the circumferential shock wave generation electrode pair, the blocking plaque can be opened in the forward direction, and shock waves can be emitted in the circumferential direction to crack or crush calcium deposits; in addition, broken calcified plaques or aortic plaques, thrombus and the like can be captured.

The invention discloses a bedside skin flap blood flow monitoring and early warning device and computing equipment, and the device comprises a skin flap tissue perfusion monitoring module which comprises a probe housing, a microcirculation blood flow velocity sensor, a tissue oxygenation degree sensor and a flexible connecting arm; the data acquisition and transmission module is used for receiving the blood flow velocity data and the oxygenation degree data through a data line and carrying out analog-to-digital conversion and data packaging; the central processing unit comprises a data storage module, a data analysis module and an early warning module; the data analysis module comprises a baseline establishment sub-module, an anomaly detection sub-module and a trend prediction sub-module; and the early warning module is used for displaying a red alarm through a bedside display screen and sending a short message alarm containing the patient name, the bed number, the early warning type and the severity information to a medical staff mobile terminal through the wireless notification module. According to the invention, the abnormal condition of skin flap blood perfusion can be found and predicted in time, and the workload of medical staff is reduced.

The invention relates to the technical field of focus positioning, in particular to a hysteromyoma focus accurate positioning method combining image analysis and data fusion, which comprises the following steps: acquiring multi-modal uterus image data, and carrying out artifact suppression and spatial registration on an original image; performing three-dimensional reconstruction on the preprocessed multi-modal image data set to generate a three-dimensional uterus model comprising anatomical structure features; lesion feature segmentation is carried out in the three-dimensional uterus model, and morphological parameters and textural features of a myoma lesion are extracted; carrying out hemodynamic analysis to obtain blood perfusion parameters and blood vessel distribution characteristics of the focus area; the blood perfusion parameters and the blood vessel distribution characteristics are fused, the three-dimensional uterus model is combined, and a focus biomechanical characteristic distribution diagram is constructed; and generating a real-time navigation path according to the biomechanical characteristic distribution diagram, and outputting a positioning report. According to the method, personalized ablation energy suggestions are made, the ablation treatment efficiency and success rate are effectively improved, the ablation energy is dynamically adjusted, and the treatment efficiency and safety are ensured.

The invention relates to a blood flow quantitative analysis method and device based on an indocyanine green contrast video. The method comprises the steps that video data of indocyanine green fluorescence contrast are collected and preprocessed; extracting dynamic change characteristics of fluorescence intensity of the blood vessel region in the time sequence by adopting an optical flow model based on brightness change; introducing a weighted cross-correlation optical flow model, and extracting dynamic information of all blood vessel regions from each video frame; based on the optical flow vector and fluorescence intensity information of the blood vessel region, blood perfusion parameters are calculated, and a global blood perfusion pseudo-color graph is generated; and selecting a region of interest on the blood perfusion pseudo-color graph to obtain the change condition of the statistical fluorescence brightness value along with time in the region of interest, and drawing a time-brightness curve for presenting the dynamic change trend of the blood flow. Compared with the prior art, the global blood perfusion graph can be generated in real time, and the dynamic change of blood perfusion of all blood vessels can be visually displayed through the time-brightness curve.

The invention relates to the technical field of medical data processing and nerve regulation and control, in particular to a method for synchronously activating post-stroke neuroplasticity through photoacoustic, which comprises the following steps of: 1, constructing a stroke specific brain region target map: fusing brain structure connection data and functional network data of a patient, generating a three-dimensional target map containing the high-metabolism semi-dark band coordinate set and the cross-hemisphere compensatory connection intersection; 2, calculating a time-space synchronization focusing parameter; 3, synchronous stimulation and dynamic regulation are executed, wherein the ultrasonic transducer and the laser source are controlled to emit time-space synchronous sound waves and light pulses; monitoring the blood perfusion variable quantity and the neurotransmitter concentration ratio of the target brain area in real time; when the blood perfusion variable quantity does not reach the expectation or the transmitter ratio is unbalanced, the stimulation intensity is dynamically adjusted, and the focusing coordinate is translated in the direction away from the infarction area. Through photoacoustic stimulation of time-space synchronization, the difference between the propagation speeds of sound waves and light waves is overcome, and accurate collaboration of neural restoration is achieved.

The invention discloses a cold therapy method based on dynamic temperature feedback and intelligent adjustment, and the method comprises the steps: loading a cold therapy preset scheme from a database of a system, and carrying out the self-inspection of equipment of a sensing layer; collecting temperature distribution information of the skin surface of the treated part of the patient to obtain thermal imaging data; acquiring blood perfusion rate information; acquiring tissue moisture content and impedance phase angle information; establishing a temperature mapping relation from the skin surface to the deep tissue; the surface boundary condition is set as the skin surface temperature actually measured by the infrared array, and the deep boundary condition is set as an adiabatic hypothesis; and fusing the acquired multi-source observation data with the numerical solution result. The system has the advantages that accurate control over the cold therapy temperature is achieved, the protection response time is optimized, the safety of a patient in the cold therapy process is guaranteed, the treatment effect is improved, a doctor can conveniently make a personalized treatment scheme, efficient information interaction between the doctor and the patient is achieved, and the treatment experience of the patient is improved.

The application provides a perfusion balloon catheter with a one-way valve, comprising: a balloon body part; the balloon body part comprises an inner lumen tube and a plurality of balloons arranged around the outer surface of the inner lumen tube; the distal balloon tube leg of the plurality of balloons is in contact with the tube wall of the inner lumen tube; a one-way valve is arranged between the inner lumen tube and the balloon part of the balloon. Compared with the prior art, the perfusion balloon catheter provided by the application is formed by a plurality of balloon clusters, and after expansion, a hollow cylindrical shape is formed, and a one-way valve is arranged in the cavity, which is used to simulate the leaflets in the heart valve, and the one-way valve is enabled after the balloon is opened, without the need for switching operation, and the structure is stable, and the function of the leaflets can be realized for multiple times; in addition, the design of the cluster balloon can reduce the difficulty of the balloon forming process while meeting the expected function.

The invention relates to the technical field of stem cells, and particularly discloses application of mesenchymal stem cells (MSC) in treatment of lower limb vein ischemia. According to the application, the SDF1-FGF2 fusion protein is used for pretreating human mesenchymal stem cells (hMSCs), and the cell activity, the blood flow recovery capacity and the anti-inflammatory effect of the hMSCs in a lower limb vein ischemia model can be remarkably improved through pretreatment. The hMSCs pretreated by SDF1-FGF2 are injected into the body of a venous ischemia model mouse, and compared with untreated cells, the hMSCs have better effects in the aspects of improving blood perfusion, reducing inflammatory response, recovering motor function and the like. The method provides an efficient stem cell treatment strategy for vascular diseases such as lower limb vein ischemia.

The invention discloses a blood glucose data analysis system and method based on artificial intelligence, relates to the technical field of diabetes management, and aims to solve the problems of blood glucose data distortion and poor blood glucose monitoring suitability of gestational diabetes patients and children diabetes patients in a motion scene. The method comprises the following steps: acquiring blood glucose original data, exercise intensity data, skin impedance data, blood perfusion index data and special crowd exclusive physiological data, preprocessing, calculating three types of interference weight factors, substituting into a calibration formula to obtain corrected blood glucose data, generating a structured report, updating the calibration formula according to a period, and optimizing a special crowd model. By means of the method, motion multi-dimensional interference can be eliminated, the small sample modeling problem of special crowds is solved, and the blood glucose data precision and clinical practicability are improved.

The invention relates to a preparation method of exosome-like nano vesicles. The preparation method comprises the following steps: extracting beet juice; performing low-speed centrifugal treatment on the beet juice, and taking supernate; carrying out medium-speed centrifugation treatment on the supernatant obtained by low-speed centrifugation, and taking the supernatant; carrying out high-speed centrifugation treatment on the supernatant obtained by medium-speed centrifugation to obtain a precipitate containing exosome-like nano vesicles; and carrying out sucrose density gradient ultracentrifugation on the obtained precipitate containing the exosome-like nano-vesicles to obtain the purified exosome-like nano-vesicles. The BELNV prepared by the invention can significantly improve the survival rate of sepsis mice, increase blood perfusion of tissues and organs of the sepsis mice, reduce pathological changes, macrophage infiltration and fibrin deposition in lung and liver tissues of the sepsis mice, and reduce blood coagulation indexes and inflammation indexes. The invention provides a novel treatment target and strategy for a treatment means of sepsis-related blood coagulation dysfunction.

The invention belongs to the technical field of medical rehabilitation instruments and biological signals, and particularly relates to a multi-mode fusion intelligent rehabilitation evaluation system based on EMG and PPG. The system comprises a flexible multi-mode sensor array module used for collecting surface electromyogram signals EMG and photoelectric volume pulse wave signals PPG and capturing muscle activation intensity and blood perfusion dynamics in real time; the self-adaptive contact enhancing module is used for driving the airbag assembly to dynamically adjust the contact pressure between the embedded pressure sensor and the skin through the micro air pump; the edge calculation unit module is used for carrying out localization processing on the collected original signals, quantitatively evaluating the collaboration of muscle activity and blood flow fluctuation and judging whether muscle contraction drives local blood flow change or not or whether vessel limitation reversely inhibits neuromuscular activation or not; and the lightweight classification model module is used for processing the time-frequency characteristics of the EMG and the waveform fragments of the PPG, and outputting rehabilitation state labels after screening key collaborative characteristics through an attention mechanism.

The utility model discloses a splenic artery blood flow limiting support, and particularly relates to the technical field of medical instruments, the splenic artery blood flow limiting support comprises a supporting support and a flow limiting support, the supporting support is sleeved outside the flow limiting support, two ends of the flow limiting support are fixedly connected with the inner side wall of the supporting support, the flow limiting support is a covered stent, and the flow limiting support comprises a contraction section and an expansion section. The contraction section and the expansion section are fixedly connected and communicated, and splenic artery blood flow in the supporting stent flows in from the contraction section and flows out from the expansion section. The splenic artery embolism postoperative spleen blood perfusion can be reduced, and the recurrence of splenic hyperfunction is reduced.

The invention discloses a primary hypertension risk assessment method based on infrared thermal imaging. The method comprises the following steps: (1) respectively taking two-hand infrared thermograms of a healthy subject, a hypertension patient and a hypertension patient before and after cold stimulation by adopting a medical infrared thermal imager; (2) analyzing hand infrared thermograms before and after cold stimulation of a healthy subject, a hypertensive patient and a hypertensive patient so as to reflect vascular reactivity and blood perfusion states of hands of the healthy subject, the hypertensive patient and the hypertensive patient; and (3) taking hand infrared thermograms of the to-be-tested subject before and after cold stimulation by adopting a medical infrared thermal imager, and obtaining a judgment result according to the vascular reactivity and blood perfusion state of the hand. According to the invention, a medical infrared thermal imager is utilized to shoot infrared thermograms of hands of a subject before and after cold stimulation, so that vascular reactivity and blood perfusion states are visually reflected in a non-contact, real-time and visualized manner, and finally, the purpose of evaluating the risk of primary hypertension is achieved.

The embodiments of the present invention relate to the field of cryoablation and disclose a cryoablation temperature prediction method, device, electronic device and storage medium, including: constructing a vascular network diagram based on the vascular centerline in the three-dimensional imaging data before the cryoablation operation, the nodes in the vascular network diagram represent the vascular bifurcation points, and the blood edges represent the vascular connection relationship; during the cryoablation process, using a pre-trained temperature prediction model to predict the temperature field of the target sampling point, the temperature prediction model includes a physical information neural network and a graph neural network; the physical information neural network uses the biological heat conduction equation as a constraint condition to predict the temperature field of the target sampling point, and the graph neural network is used to predict the blood perfusion coefficient of each node in the vascular network diagram to determine the blood perfusion coefficient contained in the biological heat conduction equation, which solves the problem of real-time prediction of cryoablation temperature in accordance with physical laws, so that the results conform to physical laws and meet the real-time requirements during the operation.

This invention discloses an intelligent psychological guidance system for harmonizing the Qi of the internal organs based on TCM emotional differentiation, belonging to the field of medical electronic equipment. The system includes a multi-node physiological signal acquisition module, a central control and data processing module, and an acoustic intervention output module. The system synchronously acquires multi-channel bioimpedance, volumetric pulse wave, and electrocardiogram signals, extracts pulse wave conduction time and local blood perfusion index, constructs Qi characteristic parameters, and maps them to generate emotional tags. The central control module locks the target resonance unlocking frequency according to the tags, modulates low-frequency vibrations with reference audio to synthesize a multimodal signal, and further combines physiological pulse transmission delay to perform phase compensation, controlling the precise output of the intervention signal during ventricular diastole. Steady-state determination and closed-loop tracking are performed based on the dynamic gradient of impedance variance. This invention achieves objective quantification of TCM differentiation and ensures high-precision physical alignment between intervention energy and the hemodynamic state of the internal organs.

The invention relates to the technical field of disease analysis, and provides an acute-stage cerebral infarction detection system and method.The method comprises the steps that basic information, physical sign data and blood sample data of a brain patient are collected, and data integration is conducted to obtain integrated data; a brain scanning image is obtained, and a high-definition brain image is obtained after artifacts are removed; recognizing image semantics, performing image segmentation, evaluating a segmentation level, and obtaining a target image when a preset level is met; identifying brain lesion features by using the target image; an angiogram is collected, the brain blood vessel caliber is calculated, and the brain blood perfusion condition is analyzed; constructing a blood vessel network by using the angiogram, and analyzing a blood vessel variation degree; based on the blood vessel caliber, the blood perfusion condition and the blood vessel variation degree, analyzing the brain blood vessel lesion degree; collecting an electroencephalogram, and analyzing brain activity characteristics; and performing acute-stage cerebral infarction analysis based on the integrated data, the brain lesion features, the brain vascular lesion degree and the brain activity features. The invention aims to improve the rationality of acute cerebral infarction detection.

This application relates to the field of biomedical engineering technology. This application discloses a method, device, terminal device and storage medium for dual-foot sole video evaluation based on plantar perfusion imaging, which can improve the accuracy of evaluation results, simplify the measurement process and enhance the patient experience. The method includes obtaining a dual-foot sole video; obtaining a plurality of left plantar rPPG signals and a plurality of right plantar rPPG signals based on the dual-foot sole video; drawing a plurality of dual-foot sole perfusion maps based on the plurality of left plantar rPPG signals and the plurality of right plantar rPPG signals; generating a target image based on the plurality of dual-foot sole perfusion maps; extracting the average value, standard deviation, maximum value and minimum value of the blood perfusion index ratio from the target image and inputting them into a classifier for evaluation processing to obtain an evaluation result, and medical staff refer to the evaluation result to diagnose peripheral artery disease and its severity.

Enhanced Thermal Imaging (ETI) is an infrared imaging modality (8-10 μm) that uses heat as a contrast agent to detect microvasculature (vessel size 0.1-5 mm) embedded in soft tissue. ETI uses an LED (535 nm±30 nm or 405 nm±30 nm) to selectively heat embedded blood vessels causing the blood to heat by approximately 0.5° C. relative to the surrounding water-rich tissue. The selective heating increases contrast in the enhanced thermal image revealing embedded microvasculature and associated blood flow.

The present invention relates to the field of stem cell technology and specifically discloses an application of mesenchymal stem cells (MSCs) for the treatment of lower extremity venous ischemia. This application involves pre-treating human mesenchymal stem cells (hMSCs) with the SDF1-FGF2 fusion protein. This pre-treatment significantly enhances the cell viability, blood flow recovery, and anti-inflammatory effects of hMSCs in a lower extremity venous ischemia model. When hMSCs pre-treated with SDF1-FGF2 were injected into mice modeling venous ischemia, they demonstrated superior effects compared to untreated cells in improving blood perfusion, reducing inflammatory responses, and restoring motor function. This method provides a highly effective stem cell therapy strategy for vascular diseases such as lower extremity venous ischemia.

This application relates to a coronary sinus and left atrium shunt system, belonging to the field of medical device technology. The system described in this application, by setting up a puncture component and a shunt component including a cutter, allows for the cutting of a portion of myocardial tissue between the coronary sinus and the left atrium, forming a shunt orifice. This establishes a shunt channel between the coronary sinus and the left atrium, effectively avoiding the embolism risk associated with atrial septal shunts and improving coronary artery blood perfusion, potentially benefiting myocardial recovery.

The utility model relates to the technical field of medical instruments, and provides an intervention guiding catheter and an intervention system.The intervention guiding catheter comprises a catheter body, a switch assembly and a traction piece; a side hole is formed in the catheter body and penetrates from the outer wall of the catheter body to the inner wall of the catheter body; the switch assembly comprises a switch piece, and the switch piece is arranged on the catheter body; the traction piece is connected with the switch piece, and the traction piece is used for pulling at least one part of the switch piece to move relative to the catheter body so as to open or close the side hole. According to the intervention guiding catheter, the side hole is provided with the switch for controlling the side hole to be opened or closed, by controlling the switch of the side hole, the side hole of the intervention guiding catheter with the side hole is opened when needed, and blood perfusion of a target blood vessel is provided for a target object; when the side hole is not needed, the side hole is closed, the usage amount of the contrast agent is reduced, and meanwhile the supporting force of the side hole specification interventional guiding catheter is improved.

The utility model relates to an alternating tangential flow perfusion system and a control method thereof, and the alternating tangential flow perfusion system comprises a consumable component, a weighing component, an air inflation component, an air exhaust component and a control box, the consumable assembly is arranged on the weighing assembly, the weighing assembly is used for monitoring the weight of fluid in the consumable assembly in real time, the control box judges the motion state of the elastic balloon according to the variable quantity of the fluid weight and the change rate of the fluid weight, and then the working states of the air inflation assembly and the air exhaust assembly are controlled; according to the alternating tangential flow perfusion system and the control method thereof, the defects in the prior art are overcome, and system operation is more stable and reliable.

The invention relates to the technical field of biology, in particular to a method for modular assembly of artery blood vessel type organs and construction of tissue microcirculation of the artery blood vessel type organs. The method comprises the following steps: inducing human pluripotent stem cells to differentiate through a mesoderm stage to form an arterial specific vascular organoid module (AVO), and then carrying out modular assembly on the AVO in vivo or in vitro so as to quickly reconstruct a tissue microcirculation network with arterial characteristics. The obtained artery blood vessel organoid is uniform in form, the diameter of the artery blood vessel organoid is intensively distributed at about 200 microns, SOX17 and CXCR4 artery endothelial markers are expressed at the same time, and the artery blood vessel organoid has polarity and a complete basilar membrane. Transplanting experiments show that the organ can be integrated with host blood vessels in a short time, and ischemic tissue blood perfusion is recovered. The defects that existing organoid is irregular, difficult to splice, delayed in perfusion and the like are overcome, and a new strategy is provided for revascularization and acute ischemic disease repair.

The application discloses a bladder cancer diagnosis and treatment integrated system and a control method thereof, which comprises a swept-frequency OCT light source, a treatment laser, a wavelength division multiplexer, a double-clad optical fiber, a flexible scanning probe, an endoscope imaging unit and an intelligent image processing and control terminal; imaging light and treatment laser are transmitted in a common light path by using the double-clad optical fiber, and scanning and light beam control are completed by means of a double-axis MEMS micro-mirror. The control method obtains tomographic structure information and depth information by reconstructing OCT data, and controls treatment laser power, galvanometer deflection and laser pause, recovery or stop by combining distance calculation, displacement compensation and blood perfusion monitoring, and is suitable for imaging navigation and closed-loop treatment in bladder cancer surgery.

The application discloses a lung ventilation-perfusion imaging area three-dimensional blood flow distribution abnormality analysis method, relates to the technical field of lung function quantitative evaluation, and comprises the following steps: acquiring lung CT image data of a patient to be analyzed, performing structure segmentation on a plurality of sections of the lung CT image data to obtain ventilation phase gray scale images and blood flow perfusion phase gray scale images; on the basis of the lung CT image data, accurately extracting a non-black lung region by threshold segmentation, respectively calculating the ratio of ventilation CT values and blood flow CT values in the region, and generating lung region segmentation data; based on the three-dimensional V / Q ratio atlas, identifying abnormal sub-regions in which local ventilation blood flow ratios deviate from physiological ranges; and obtaining a blood flow distribution abnormality analysis report by performing structured analysis on the abnormal sub-regions. The application divides irregular sub-regions by performing a K-means clustering algorithm on gray scale values in each section, realizes adaptive segmentation of lung function heterogeneity structures, and improves the rationality of local ratio calculation.

The invention discloses a coronary medicine balloon dilatation catheter, and belongs to the technical field of medical instruments. In order to solve the problems that an existing drug balloon is high in blood flow blocking risk, large in drug loss and uneven in drug distribution, the balloon dilatation catheter comprises a catheter body, a dilatation balloon, a drug delivery catheter, a drug storage bin, a driving connecting rod, a connecting ring and a guiding head. The dosing catheter protrudes out of the periphery of the dilatation balloon at intervals, the flexible side wall of the medicine storage bin communicates with the liquid injection cavity channel, and the driving connecting rod drives the dosing catheter to rotationally apply medicine through spiral transmission; the catheter body is provided with an independent blood flow cavity channel and a blood inlet, and a gap formed by the catheter body and the administration catheter forms a double-channel blood flow path. The invention realizes the synergy of vasodilatation, accurate and uniform administration and continuous blood perfusion, reduces drug loss and non-targeted deposition, reduces myocardial ischemia complications and postoperative restenosis risk, is simple and convenient to operate, and is suitable for various coronary heart disease treatment scenes.

The embodiment of the invention relates to the field of cryoablation, and discloses a cryoablation temperature prediction method and device, electronic equipment and a storage medium, and the method comprises the steps: building a blood vessel network diagram based on a blood vessel center line in three-dimensional image data before a cryoablation operation, enabling nodes in the blood vessel network diagram to represent blood vessel bifurcation points, and enabling blood edges to represent a blood vessel connection relation; in the cryoablation process, a pre-trained temperature prediction model is used for predicting a temperature field of the target sampling point, and the temperature prediction model comprises a physical information neural network and a graph neural network; the physical information neural network predicts a temperature field of the target sampling point by taking a biological heat conduction equation as a constraint condition, and the graph neural network is used for predicting a blood perfusion coefficient of each node in the blood vessel network graph so as to determine a blood perfusion coefficient included in the biological heat conduction equation; the problems that the cryoablation temperature is predicted in real time and conforms to the physical law are solved, and the result conforms to the physical law and meets the real-time requirement in an operation.

The invention provides a stroke risk time sequence management-oriented multi-modal data-driven acupoint regulation and self-optimization intervention method and system, and relates to the technical field of medical health information processing. The skin temperature, the heart rate, the infrared blood perfusion, the activity intensity and the sleep state are continuously collected, data cleaning and feature modeling are carried out, a prediction model is trained in combination with historical intervention results, and the optimal intervention opportunity, duration and safety boundary of the day are generated; acupuncture points and execution units are determined according to a planned object, physiological signals are collected in real time, the slow release rate or stimulation intensity is dynamically adjusted, and control is conducted through safety boundary and dose constraint; the risk and stability are calculated based on data and adjustment records before, during and after intervention, a prediction model is updated, a plan of the next day is generated, individualized closed-loop management of monitoring, decision making, execution and feedback is achieved, and the safety and effectiveness of stroke risk intervention are improved.

The application provides a myocardial infarction detection system based on diffusion speckle, and relates to the field of wearable health detection.The system comprises a laser for exciting a laser signal;an optical fiber probe connected with the laser through a multimode optical fiber for guiding the laser signal to a to-be-detected object and collecting a reflected light signal of the to-be-detected object;a camera connected with the optical fiber probe through a multimode optical fiber for obtaining a diffusion speckle image based on the reflected light signal;and a processing device electrically connected with the camera for obtaining an initial blood perfusion index signal and an initial pulse wave signal based on the diffusion speckle image, reconstructing the initial blood perfusion index signal and the initial pulse wave signal respectively to obtain a target blood perfusion index signal and a target pulse wave signal, and performing myocardial infarction detection based on the target blood perfusion index signal and the target pulse wave signal.