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Infant extracorporeal circulation pre-filling liquid ultrafiltration device and method

A technology of extracorporeal circulation and pre-filling fluid, applied in ultrafiltration, blood circulation treatment, chemical instruments and methods, etc., can solve problems such as prolonging operation time, increasing physical injury of children, reducing inflammatory reaction and reducing hospitalization time. , the effect of reducing blood transfusion

Pending Publication Date: 2021-11-02
CHANGZHOU CHILDRENS HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] In the prior art, the balanced ultrafiltration method is usually used. The balanced ultrafiltration technology can correct the acid-base imbalance and electrolyte disorder caused by the operation, reduce the gradually increasing inflammatory media during the operation, and improve the ultrafiltration after the operation to make the internal environment more stable. Close to normal physiological conditions; but the improved ultrafiltration takes a certain amount of time to achieve a close to normal internal environment of the human body, prolonging the operation time and increasing the physical harm to the children

Method used

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  • Infant extracorporeal circulation pre-filling liquid ultrafiltration device and method

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Effect test

Embodiment 1

[0030] refer to figure 1 , infant extracorporeal circulation priming solution ultrafiltration device, including blood storage bottle 1, main pump 2, oxygenator 3, microembolus filter 4 connected through connecting pipeline 71 in sequence, and also includes slave pump 5 and ultrafiltration system 6 , the liquid outlet of the micro plug filter 4 is connected with the sub-pump 5 through the first connection pipe 72, and the sub-pump 5 is connected with the ultrafiltration system 6 through the second connection pipe 73, and the outlet of the ultrafiltration system 6 It is connected with the patient's venous cannula through a liquid delivery tube 74, and the first connecting tube 72 is provided with a return tube 75, and the return tube 75 connects the sub-pump 5 and one end of the patient's arterial cannula;

[0031] The ultrafiltration system 6 includes an ultrafilter 61, a negative pressure aspirator 65 communicated with the ultrafilter 61, a gas supply cylinder 62 with a regula...

Embodiment 2

[0034] The ultrafiltration method for priming fluid in extracorporeal circulation of infants and young children adopts the ultrafiltration device for priming fluid in extracorporeal circulation of infants and young children described in Example 1, comprising the following steps:

[0035] Step a, mix the priming solution, mix 1.5-2.5IU of leukocyte-reduced suspension, 150-300mL of plasma, 150-300mL of crystalloid, and 10-30mg of heparin, and then put it into a blood storage bottle. The crystalloid is glucose salt, acetate, one or more of compound electrolyte injection, mannitol, and colloid; the colloid is one or more of albumin, plasma, and gelatin; the perfusate is compound electrolyte injection,

[0036] Step b, normal ultrafiltration of the priming fluid, pump the priming fluid in the blood storage bottle into the oxygenator through the main pump, and perform the first membrane filtration; the priming fluid treated by the oxygenator enters the micro plug filtration Filter ...

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Abstract

The invention relates to an infant extracorporeal circulation pre-filling liquid ultrafiltration device and method. The ultrafiltration device comprises a blood storage bottle, a main pump, an oxygenator, a microembolus filter, a branch pump and an ultrafiltration system which are sequentially connected, wherein the liquid outlet of the microembolus filter is connected with the branch pump through a first connecting pipe, the branch pump is connected with the ultrafiltration system through a second connecting pipe, the outlet of the ultrafiltration system is connected with a venous cannula of a child patient through a liquid feeding pipe, a reflux pipe is arranged on the first connecting pipe, the reflux pipe is connected with the branch pump and the arterial cannula of the child patient, the device further comprises a blood gas analyzer, and the blood gas analyzer is linked with a perfusion pump. The ultrafiltration method comprises the steps of pre-filling liquid mixing, pre-filling liquid common ultrafiltration, pre-filling liquid balance ultrafiltration, intraoperative perfusion blood balance ultrafiltration and improved ultrafiltration after extracorporeal circulation is stopped after the operation is finished. According to the device and the method, combined ultrafiltration is carried out on perfused blood in the periextracorporeal circulation period, the operation time can be effectively shortened, inflammatory response is reduced, damage to the body is reduced, and the extracorporeal circulation safety is improved, so that the recovery period of a child patient is shortened.

Description

technical field [0001] The invention belongs to the technical field of extracorporeal circulation, and in particular relates to an ultrafiltration device and method for prefilling liquid in extracorporeal circulation of infants and young children. Background technique [0002] With the development of cardiac surgery, extracorporeal circulation technology for infants and young children is constantly improving. The difference between children and adults is not only the difference in weight and size. The renal drainage function is incomplete, and the resistance to systemic inflammatory response syndrome is poor, and extracorporeal circulation is more likely to cause lung injury. [0003] In order to meet the appropriate hematocrit during extracorporeal circulation of infants and young children, it is necessary to add oligoplasmic blood to the priming solution. The source of oligoplasmic blood is stock blood. The concentration of sexual media, bradykinin, and complement increas...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): B01D61/14B01D61/18A61M1/36
CPCB01D61/18A61M1/3607A61M1/3643B01D61/146
Inventor 钮建宏匡荣赵静周娟英
Owner CHANGZHOU CHILDRENS HOSPITAL
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