Boron neutron capture therapy equipment and method based on high-energy electron accelerator

Abstract

The invention relates to the technical field of medical instruments, in particular to boron neutron capture therapy equipment and method based on a high-energy electron accelerator, and the equipment comprises the electron accelerator which is used for accelerating input electrons and generating high-energy electrons after acceleration; the high Z conversion target is used for converting the high-energy electrons into high-energy X rays and converting the high-energy X rays into photoneutrons; the neutron slowing-down body is used for slowing down photoneutrons; and the controller is used for controlling the electron accelerator to generate high-energy electrons according to a control instruction of an operator, the electron accelerator emits the high-energy electrons to bombard the high-Z conversion target to obtain photoneutrons, the photoneutrons are moderated by the neutron moderator to generate moderated neutrons, and the moderated neutrons are used for performing irradiation treatment on the to-be-treated person. The equipment can effectively improve the stability of neutron source output in the low-boron neutron capture therapy process, and improve the therapy effect and the use experience.

Description

technical field [0001] The invention relates to the technical field of medical devices, in particular to a boron neutron capture therapy device and method based on a high-energy electron accelerator. Background technique [0002] BNCT (Boron Neutron Capture Therapy) is a very valuable cancer technology that uses the following nuclear reactions to kill cancer cells: [0003] [0004] Among them, n is the neutron injected into the human body, 10 B is the neutron-absorbing atomic nucleus that enters the human body in the form of drugs and is enriched at the lesion. neutron and 10 B undergoes an absorption reaction and releases a large amount of energy, 6.1% of which is 2.79MeV, and 93.9% of which is 2.31MeV. The energy released by 7 Li nuclei and α particles are carried, and their range in the cell is only on the order of μm, so the ionization effect can occur in the cell to deposit energy and kill the cell. [0005] In related technologies, since the type of hadrons ca...

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Problems solved by technology

[0006] However, hadron accelerators can only accelerate hadrons to the level of 10MeV. At this time, the range of protons, deuterons, etc. in the target material is very short, only on the order of mm, so a large amount of them will be deposited in a very shallow depth of the target material. At the same time, after each neutron is produced, protons and alpha particles will be produced, which will form the deposition of hydrogen atoms and helium atoms in the target, resulting in hydrogen embrittlement and helium embrittlement, and finally make the target rupture

As a result, the stability of the neutron source output during boron neutron capture therapy is greatly reduced, the effect of boron neutron capture therapy is reduced, and the user experience is reduced

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