Method and device for eliminating Fourier deconvolution ion mobility spectrometry baseline ambiguity

Abstract

The invention provides a method and device for eliminating Fourier deconvolution ion mobility spectrometry baseline ambiguity, and the method comprises the steps: employing a Fourier deconvolution gating unit to generate a Fourier deconvolution gating modulation pulse signal, and transmitting the signal to an ion gate control unit to achieve the multiplexing control of an ion gate, and performing Fourier deconvolution on an ion signal collected by a detector and the gating modulation pulse signal to obtain an ion mobility spectrometry primary signal, and performing ion gate induction pulse zero filling, Fourier transform, low-pass filtering and inverse Fourier transform on the ion mobility spectrometry primary signal to obtain an ion mobility spectrometry. According to the method, Fourier deconvolution ion mobility spectrometry baseline ambiguity can be eliminated, interference of ion gate induction pulses on effective signals is eliminated, the signal-to-noise ratio of the Fourier deconvolution ion mobility spectrometry is improved, and the analysis and recognition capability of the ion mobility spectrometry is improved.

Description

technical field [0001] The invention belongs to the field of analytical instruments, and specifically relates to a method and a device for eliminating baseline variation of Fourier deconvolution ion mobility spectra. Background technique [0002] Ion Mobility Spectrometry (IMS) is a rapid detection and analysis technique for compound molecular ions to collide with neutral gas molecules in a uniform electric field and achieve atmospheric pressure separation at different rates. It has the advantages of simple structure, high sensitivity, good stability and fast detection speed. and low analysis cost. [0003] The most common ion gates of ion mobility spectrometers are TP ion gates and BN ion gates, and the control of ion gates usually uses the ion gate control unit to adjust the voltage of the two groups of electrodes of the ion gate to realize the switch of the ion gate; when When the potentials of the two groups of electrodes of the ion gate are equal, the ion gate is opene...

AI Technical Summary

Problems solved by technology

Although part of the baseline interference can be offset by subtracting the background, it greatly affects the authenticity of the spectrum and the reliability and stability of the data, which restricts the further improvement of the performance of the micro ion mobility spectrometer.

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