Microneedle patch and permeation enhancing device

Abstract

The present application provides a microneedle patch having a substance to be permeated; the microneedle patch comprises a patch base material and at least one microneedle, and when the patch base material is attached to the skin, the microneedle pierces the skin to promote penetration of functional substances into the skin. The invention further provides a permeation promoting device which comprises a body, a controller, an ultrasonic module and an ion module, an acting end is arranged at one end of the body, a holding part is formed at the other end of the body, the controller is arranged in the body, the ultrasonic module is arranged in the acting end and electrically connected with the controller, and the ion module is electrically connected with the controller. The ion module comprises a first electrode and a second electrode which are connected with the controller, the first electrode is a metal conductive part of which the acting end can be in contact with the skin, and the second electrode is arranged on the holding part; the controller controls the ultrasonic module and / or the ion module to start working and enables the acting area to be used in cooperation with the at least one microneedle patch so as to promote permeation of the functional substance. The microneedle patch can be used independently and can also be used in cooperation with ultrasonic and ion infiltration promotion, and the infiltration promotion effect is good.

Description

technical field [0001] The invention relates to the technical field of permeation-promoting devices, in particular to a microneedle patch applied to the skin and a permeation-promoting device. Background technique [0002] The human epidermis has many layers maintained by keratinocytes. The proliferation of these cells results in the migration of mature cells towards the outer layer of the epidermis, the stratum corneum. This external barrier consists of a 15-20 micron thick stratum corneum filled with keratinized dead cells, with a "brick and mortar" structure. The above-mentioned innate structural properties of the epidermis form a very strong barrier against foreign invasion, and only very small hydrophobic molecules such as clonidine, nicotine, nitroglycerin, etc. can penetrate through the skin. Usually compound human collagen, amino acid, hyaluronic acid, toner, lotion, muscle base, eye cream, face cream, whitening water, gel and other penetration-promoting equipment ...

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