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Feed additive containing acidifier as well as preparation method and application of feed additive

The technology of feed additive and acidifier is applied in the field of feed additive containing acidifier and its preparation, which can solve the problems of destroying nutrients and the like, and achieve the effects of improving convenience of use, excellent acidifying effect and realizing slow-release effect.

Active Publication Date: 2022-07-29
江苏翼邦生物技术有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In order to achieve the purpose of acidifying the intestinal tract, acidifiers are often added to the feed several times more than the actual requirement, but excessive acidifiers will greatly increase the acidity of the feed and destroy other nutrients in the feed

Method used

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  • Feed additive containing acidifier as well as preparation method and application of feed additive
  • Feed additive containing acidifier as well as preparation method and application of feed additive
  • Feed additive containing acidifier as well as preparation method and application of feed additive

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0039] An acidulant-containing feed additive, comprising a core body and a sustained-release coating layer arranged on the outside of the core body, and a preparation method thereof, comprising the following steps:

[0040] ①, the preparation of core material

[0041] Weigh 156g of polycaprolactone and place it at 70°C (it is allowed to fluctuate in the temperature range of 60-80°C) and heat it to melt, add 406g of acidulant, stir evenly and add 188g of disintegrant, continue to stir until the material is evenly dispersed, with After cooling at a speed of 10°C / s, it is ground into powder and passed through a 100-mesh sieve to obtain the core material for forming the shell;

[0042] Wherein, the acidulant is a mixture of citric acid, fumaric acid, sorbic acid, propionic acid and hydrochloric acid in a weight ratio of 5:5:2:1:1; the disintegrant can be sodium carboxymethyl starch, low-substituted hydroxyl One or more mixtures of propyl cellulose, cross-linked polyvinyl pyrrolid...

Embodiment 2-4

[0048] In Examples 2-4, on the basis of the method in Example 1, the dosages of the components of the core and the sustained-release coating layer were adjusted, and the specific adjustment is shown in Table 1 below.

[0049] The dosage adjustment table of table one embodiment 1-4 (unit g)

[0050]

Embodiment 5-9

[0088] In Examples 5-9, on the basis of the method and components of Example 1, the weight ratio of the core body and the sustained-release coating layer was adjusted, and the specific adjustment situation is shown in Table 6 below.

[0089] The weight ratio of the core body and the sustained-release coating layer of Table 6 Examples 1 and 5-9

[0090] weight ratio Example 1 3:1 Example 5 9:1 Example 6 8:1 Example 7 6:1 Example 8 4:1 Example 9 2:1

[0091] The above-mentioned feed additives prepared in Examples 5-9 were subjected to the above moisture absorption performance test, gastric juice release degree and intestinal juice release degree test, and experimental animal effect test, and the detection results are shown in Table 7-Table 9.

[0092] Table 7 Moisture content of Examples 1, 5-9 (unit: %)

[0093] test group Day 1 Day 7 Day 14 Day 28 Example 1 3.02 3.10 3.21 3.35 Example 5 3.04 ...

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Abstract

The invention relates to the technical field of feed additives, in particular to a feed additive containing an acidifying agent and a preparation method and application of the feed additive. The feed additive containing the acidifying agent comprises a core body and a slow-release coating layer arranged on the outer side of the core body, and the core body and the slow-release coating layer are compounded into a whole through irradiation treatment; the core body comprises the following components in parts by weight: 50-80 parts of an acidifying agent, 20-30 parts of polycaprolactone and 30-40 parts of a disintegrating agent; the slow-release coating layer is prepared from the following components in parts by weight: 60 to 80 parts of polyhydroxybutyrate, 20 to 30 parts of polyethylene glycol, 5 to 15 parts of an acidifying agent and 5 to 10 parts of trehalose. The feed additive has a good slow-release effect in gastric juice and intestinal tracts, is helpful for improving the biological immunity, is small in dosage in a feed formula, has a good acidification effect on the gastric juice and the intestinal tracts, and can also effectively improve the use convenience of an acidifying agent in feed.

Description

technical field [0001] The application relates to the technical field of feed additives, in particular to an acidulant-containing feed additive and a preparation method and application thereof. Background technique [0002] In pet feeding, antibiotics are widely added to pet feed because they can effectively prevent the infection of pet intestinal pathogens and promote the healthy growth of pets. However, the abuse of antibiotics has become an important hidden danger affecting pet health. At present, reducing or even replacing antibiotics in pet feed is of great significance to pet health. Studies have shown that the pH value in the animal intestine is of great significance for inhibiting pathogenic bacteria. Therefore, the use of acidifiers in the feed industry to change the pH value in the animal intestine and improve immunity has become a common method. [0003] At present, the commonly used acidifiers enter the pet's body with the feed, most of which are decomposed, dig...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23K20/105A23K20/26A23K20/20A23K20/163A23K20/132A23K40/30A23K40/10A23K50/00A23K50/50
CPCA23K20/105A23K20/26A23K20/20A23K20/163A23K20/132A23K40/30A23K40/10A23K50/00A23K50/50Y02P60/87
Inventor 殷军欧锦强
Owner 江苏翼邦生物技术有限公司
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